Pore Network Simulation of Gas-Liquid Distribution in Porous Transport Layers

Pore network models are powerful tools to simulate invasion and transport processes in porous media. They are widely applied in the field of geology and the drying of porous media, and have recently also received attention in fuel cell applications. Here we want to describe and discuss how pore network models can be used as a prescriptive tool for future water electrolysis technologies. In detail, we suggest in a first approach a pore network model of drainage for the prediction of the oxygen and water invasion process inside the anodic porous transport layer at high current densities. We neglect wetting liquid films and show that, in this situation, numerous isolated liquid clusters develop when oxygen invades the pore network. In the simulation with narrow pore size distribution, the volumetric ratio of the liquid transporting clusters connected between the catalyst layer and the water supply channel is only around 3% of the total liquid volume contained inside the pore network at the moment when the water supply route through the pore network is interrupted; whereas around 40% of the volume is occupied by the continuous gas phase. The majority of liquid clusters are disconnected from the water supply routes through the pore network if liquid films along the walls of the porous transport layer are disregarded. Moreover, these clusters hinder the countercurrent oxygen transport. A higher ratio of liquid transporting clusters was obtained for greater pore size distribution. Based on the results of pore network drainage simulations, we sketch a new route for the extraction of transport parameters from Monte Carlo simulations, incorporating pore scale flow computations and Darcy flow

Diffusion of small two-dimensional Cu islands on Cu(111) studied with a kinetic Monte Carlo method

Diffusion of small two-dimensional Cu islands (containing up to 10 atoms) on Cu(111) has been studied using the newly developed self-learning Kinetic Monte Carlo (SLKMC) method which is based on a database of diffusion processes and their energetics accumulated automatically during the implementation of the SLKMC code. Results obtained from simulations in which atoms hop from one fcc hollow site to another are compared with those obtained from a parallel set of simulations in which the database is supplemented by processes revealed in complementary molecular dynamics simulations at 500K. They include processes involving the hcp (stacking-fault) sites, which facilitate concerted motion of the islands (simultaneous motion of all atoms in the island). A significant difference in the scaling of the effective diffusion barriers with island size is observed in the two cases. In particular, the presence of concerted island motion leads to an almost linear increase in the effective diffusion barrier with size, while its absence accounts for strong size-dependent oscillations and anomalous behavior for trimers and heptamers. We also identify and discuss in detail the key microscopic processes responsible for the diffusion and examine the frequencies of their occurrence, as a function of island size and substrate temperature.Peer reviewe

Framework Report: The AIDS Accountability Workplace Scorecard, September 2011

The aim of the AIDS Accountability Workplace Scorecard is to improve HIV and AIDS workplace programmes in the countries and sectors most affected by the disease, and improve the health of employees, their families and communities. Through this initiative we will: / 1. Provide tools for HIV and AIDS workplace programme monitoring and evaluation AAI has developed scorecard tools for small, medium and large workplaces, which can be used to assess a global, regional or national HIV and AIDS programme or interventions at a specific workplace site. The scorecards can serve as both internal monitoring and evaluation tools and as assessments to present to stakeholders within and outside the organization. / 2. Publish annual Rankings of HIV and AIDS Workplace Programmes Scorecard users who wish to receive a ranking analysis and recommendations for how to improve their programmes can submit their scorecards to AAI. AAI ‘s ranking analysis will allow users to compare their performance with others and over time also measure their own progress. Respondents will be encouraged to publish their ranking in AAI’s yearly Ranking Reports. / 3. Share good practice The knowledge and good practices generated through the published rankings will be used to stimulate improved HIV and AIDS Workplace Programmes worldwide. Large networks of companies, trade union confederations, and national and international organizations can use the scorecard as a common framework for monitoring and evaluation of workplace programmes

The role of multiple marks in epigenetic silencing and the emergence of a stable bivalent chromatin state

We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built upon known biomolecular interactions in the system. Doing so, we identify the epigenetic marks essential for the bistability of epigenetic states. The model explicitly incorporates two key chromatin marks, namely H4K16 acetylation and H3K79 methylation, and explores whether the presence of multiple marks lead to a qualitatively different systems behavior. We find that having both modifications is important for the robustness of epigenetic silencing. Besides the silenced and transcriptionally active fate of chromatin, our model leads to a novel state with bivalent (i.e., both active and silencing) marks under certain perturbations (knock-out mutations, inhibition or enhancement of enzymatic activity). The bivalent state appears under several perturbations and is shown to result in patchy silencing. We also show that the titration effect, owing to a limited supply of silencing proteins, can result in counter-intuitive responses. The design principles of the silencing system is systematically investigated and disparate experimental observations are assessed within a single theoretical framework. Specifically, we discuss the behavior of Sir protein recruitment, spreading and stability of silenced regions in commonly-studied mutants (e.g., sas2, dot1) illuminating the controversial role of Dot1 in the systems biology of yeast silencing.Comment: Supplementary Material, 14 page

Characterization of complex networks: A survey of measurements

Each complex network (or class of networks) presents specific topological features which characterize its connectivity and highly influence the dynamics of processes executed on the network. The analysis, discrimination, and synthesis of complex networks therefore rely on the use of measurements capable of expressing the most relevant topological features. This article presents a survey of such measurements. It includes general considerations about complex network characterization, a brief review of the principal models, and the presentation of the main existing measurements. Important related issues covered in this work comprise the representation of the evolution of complex networks in terms of trajectories in several measurement spaces, the analysis of the correlations between some of the most traditional measurements, perturbation analysis, as well as the use of multivariate statistics for feature selection and network classification. Depending on the network and the analysis task one has in mind, a specific set of features may be chosen. It is hoped that the present survey will help the proper application and interpretation of measurements.Comment: A working manuscript with 78 pages, 32 figures. Suggestions of measurements for inclusion are welcomed by the author

Evaluation of Antioxidant and Antimicrobial Potential of Two Endangered Plant Species Atropa belladonna and Matricaria chamomilla

Background: Plants are the natural source of antioxidants as well as antimicrobial compounds that has great potentials in pharmaceuticalindustry. In the present study, two medicinal plants Atropa belladonna and Matricaria chamomilla were collected from Northern areas ofPakistan.Materials and Methods: The extracts of the collected plants were obtained by microwave assisted extraction (MAE) with changing parameters, power level and time; methanol and ethanol were solvents used during  extraction. The extracts of plants were tested against different bacterialstrains.Results: It was observed that ethanolic extracts of Atropa belladonna has more significant antimicrobial activity against S.aureus than E.coli. Inparallel, methanolic extract of Matricaria chamomilla showed greater significant antibacterial activity against S.aureus when compared withE.coli. In comparison, ethanolic extracts of Matricaria chamomilla has shown more significant results against S. aureus than E.coli (p.0.05).Both plants had no antibacterial activity against S.typhi. The free radical scavenging activity observed by DPPH assay, indicate that both plantshave antioxidant activity at all levels of concentrations in solvent tested during the present work. However, methanolic extracts had greaterantioxidant activity when compared with ethanolic extracts.Conclusion: Present study is thus helpful in highlighting present potentials for antioxidant and antimicrobial properties in the selected plants.Key words: Antimicrobial, antioxidant, Atropa belladonna, Matricaria chamomill

Adaptive robust video broadcast via satellite

© 2016 Springer Science+Business Media New YorkWith increasing demand for multimedia content over channels with limited bandwidth and heavy packet losses, higher coding efficiency and stronger error resiliency is required more than ever before. Both the coding efficiency and error resiliency are two opposing processes that require appropriate balancing. On the source encoding side the video encoder H.264/AVC can provide higher compression with strong error resiliency, while on the channel error correction coding side the raptor code has proven its effectiveness, with only modest overhead required for the recovery of lost data. This paper compares the efficiency and overhead of both the raptor codes and the error resiliency techniques of video standards so that both can be balanced for better compression and quality. The result is also improved by confining the robust stream to the period of poor channel conditions by adaptively switching between the video streams using switching frames introduced in H.264/AVC. In this case the video stream is initially transmitted without error resiliency assuming the channel to be completely error free, and then the robustness is increased based on the channel conditions and/or user demand. The results showed that although switching can increase the peak signal to noise ratio in the presence of losses but at the same time its excessive repetition can be irritating to the viewers. Therefore to evaluate the perceptual quality of the video streams and to find the optimum number of switching during a session, these streams were scored by different viewers for quality of enhancement. The results of the proposed scheme show an increase of 3 to 4 dB in peak signal to noise ratio with acceptable quality of enhancement

Deciphering the drought tolerance mechanisms in citrus rootstocks

An increasing amount of land is becoming unsuitable for citrus cultivation, mainly due to water scarcity. This study evaluated the physiological and biochemical performance of trifoliate orange (Poncirus trifoliata) and rough lemon (Citrus jambhiri) seedlings subjected to water deficit for 12 days. Under these conditions, trifoliate orange was more sensitive than rough lemon and exhibited significant changes in LRWC (64.8% vs 36.7%), gas exchange parameters (71.7% vs 54.3% on average), leaf surface area (18.2% vs 4.9%), chlorophyll fluorescence in dark- and light-adapted leaves (44.5% vs 33.3% on average) and non-photochemical quenching (94.3% vs 28.2%). Moreover, oxidative stress indicators, such as malondialdehyde or hydrogen peroxide, indicated significantly higher values in trifoliate orange than in rough lemon seedlings. They also showed lower antioxidant defense activation. Other biochemical parameters, such as proline, glycine betaine, antioxidant capacity, phenolic content, and total soluble proteins, showed higher levels in rough lemon than in trifoliate orange seedlings. Overall, the better performance of rough lemon in arid conditions could be attributed to its improved ability to prevent water loss and maintain tissue water content. In addition, rough lemon has a more robust antioxidant defense to keep production of reactive oxygen species at low levels

Fabrication of Microbicidal Silver Nanoparticles: Green Synthesis and Implications in the Containment of Bacterial Biofilm on Orthodontal Appliances

Among various metal-based nanoparticles, silver nanoparticles (AgNPs) manifest superior inhibitory effects against several microorganisms. In fact, the AgNP-based treatment has been reported to inhibit both sensitive and resistant isolates of bacteria and other disease-causing microbes with equal propensity. Keeping this fact into consideration, we executed bio-mediated synthesis of AgNPs employing extract of flower and various other parts (such as bud and leaf) of the Hibiscus rosa-sinensis plant. The physicochemical characterization of as-synthesized AgNPs was executed employing transmission electron microscopy (TEM), dynamic light scattering (DLS), zeta potential, Fourier transform infrared (FTIR) spectroscopy, and UV-Vis spectroscopy, etc. The as-synthesized AgNPs demonstrated strong antimicrobial activity against both Gram-positive and Gram-negative bacteria with equal propensity. The as-synthesized AgNPs successfully inhibited Streptococcus mutans (S. mutans), one of the main causative bacteria responsible for dental caries. Considering the fact that orthodontic appliances facilitate infliction of the oral cavity with a range of microbes including S. mutans, we determined the growth inhibitory and anti-adherence activities of AgNPs on orthodontic appliances. We performed microbiological assays employing AgNPs adsorbed onto the surface of nickel–titanium (Ni-Ti) orthodontic wires. A topographic analysis of the decontaminated Ni-Ti orthodontic wires was performed by scanning electron microscopy. In addition to antimicrobial and anti-biofilm activities against oral S. mutans, the as-fabricated AgNPs demonstrated significant inhibitory and anti-biofilm properties against other biofilm-forming bacteria such as Escherichia coli and Listeria monocytogenes

Virtual reality as a non-conventional rehabilitation for stroke: : A comprehensive review

The authors thank Michael Irvine, PhD, from Liwen Bianji (Edanz) (www.liwenbianji.cn) for editing the English text of a draft of this manuscript.Peer reviewe