1,174 research outputs found
Offset-fed UWB antenna with multi-slotted ground plane
This paper presents the design and results of an offset feed Ultrawideband(UWB) antenna with a multiple-slotted ground plane. The antenna consists of a square shaped radiator, a feed slightly offset from the middle along the radiator side and a ground plane with multiple rectangular slots. Simulation results show that the antenna can achieve a wide bandwidth from 3.3 to 18 GHz. © 2011 IEEE.published_or_final_versionThe 2011 International Workshop on Antenna Technology (iWAT), Hong Kong, China, 7-9 March 2011. In Proceedings of iWAT, 2011, p. 432-43
Analytical reasoning task reveals limits of social learning in networks
Social learning -by observing and copying others- is a highly successful
cultural mechanism for adaptation, outperforming individual information
acquisition and experience. Here, we investigate social learning in the context
of the uniquely human capacity for reflective, analytical reasoning. A hallmark
of the human mind is our ability to engage analytical reasoning, and suppress
false associative intuitions. Through a set of lab-based network experiments,
we find that social learning fails to propagate this cognitive strategy. When
people make false intuitive conclusions, and are exposed to the analytic output
of their peers, they recognize and adopt this correct output. But they fail to
engage analytical reasoning in similar subsequent tasks. Thus, humans exhibit
an 'unreflective copying bias,' which limits their social learning to the
output, rather than the process, of their peers' reasoning -even when doing so
requires minimal effort and no technical skill. In contrast to much recent work
on observation-based social learning, which emphasizes the propagation of
successful behavior through copying, our findings identify a limit on the power
of social networks in situations that require analytical reasoning
Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution.
The enzyme porphobilinogen deaminase (PBGD; hydroxymethylbilane synthase; EC 2.5.1.61) catalyses an early step of the tetrapyrrole-biosynthesis pathway in which four molecules of the monopyrrole porphobilinogen are condensed to form a linear tetrapyrrole. The enzyme possesses a dipyrromethane cofactor, which is covalently linked by a thioether bridge to an invariant cysteine residue (Cys241 in the Bacillus megaterium enzyme). The cofactor is extended during the reaction by the sequential addition of the four substrate molecules, which are released as a linear tetrapyrrole product. Expression in Escherichia coli of a His-tagged form of B. megaterium PBGD has permitted the X-ray analysis of the enzyme from this species at high resolution, showing that the cofactor becomes progressively oxidized to the dipyrromethene and dipyrromethanone forms. In previously solved PBGD structures, the oxidized cofactor is in the dipyromethenone form, in which both pyrrole rings are approximately coplanar. In contrast, the oxidized cofactor in the B. megaterium enzyme appears to be in the dipyrromethanone form, in which the C atom at the bridging α-position of the outer pyrrole ring is very clearly in a tetrahedral configuration. It is suggested that the pink colour of the freshly purified protein is owing to the presence of the dipyrromethene form of the cofactor which, in the structure reported here, adopts the same conformation as the fully reduced dipyrromethane form
Using mapped quantitative trait loci in improving genetic evaluation
The benefit of using QTL information in dairy cattle breeding schemes by means of computer simulation is investigated. In addition, algorithms to overcome computational problems arising when marker data are included in mixed linear models were proposed.;Computer simulation was conducted with parameters relative to the Holstein population of the United States. Superiority of QTL-assisted selection (QAS) over QTL-free selection was studied in four pathways of selection, namely active sires, young bulls, bull dams, and cows, for cumulative genetic response, accuracy of evaluation, and selection pressure on the QTL.;Further, breeding scheme as a factor was studied. The breeding scheme was the most effective factor in increasing the superiority of QAS. As it agreed with many previous studies, nucleus breeding schemes were found to be promising systems to implement QTL information. On the other hand, benefits of QAS in conventional two stage selection programs were limited.;The interaction between the type of QTL information available and the breeding system was found important. Using a highly polymorphic QTL in nucleus schemes was found very effective. Effects of different number of alleles per locus and different number of loci on the superiority of QAS were studied.;An algorithm to directly build the inverse of a conditional gametic relationship matrix, given marker data, was developed. The inverse algorithm is based on matrix decomposition instead of partitioned matrix theory. Numerical techniques that greatly improved computing performance were introduced.;Appropriate modifications to the conventional breeding schemes that are currently in use are highly recommended. Further, attention should be paid to the characteristics of the QTL and how they may interact with the breeding system, e.g., number of loci and alleles. Finally, the study found that the use of marked or known QTL information in genetic evaluation is computationally possible and generally useful
GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia.
We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival (CRFS) among pediatric patients with acute leukemia (n = 1613) who underwent transplantation with 1 antigen-mismatched (7/8) bone marrow (BM; n = 172) or umbilical cord blood (UCB; n = 1441). Multivariate analysis was performed using Cox proportional hazards models. To account for multiple testing, P \u3c .01 for the donor/graft variable was considered statistically significant. Clinical characteristics were similar between UCB and 7/8 BM recipients, because most had acute lymphoblastic leukemia (62%), 64% received total body irradiation-based conditioning, and 60% received anti-thymocyte globulin or alemtuzumab. Methotrexate-based GVHD prophylaxis was more common with 7/8 BM (79%) than with UCB (15%), in which mycophenolate mofetil was commonly used. The univariate estimates of GRFS and CRFS were 22% (95% confidence interval [CI], 16-29) and 27% (95% CI, 20-34), respectively, with 7/8 BM and 33% (95% CI, 31-36) and 38% (95% CI, 35-40), respectively, with UCB (P \u3c .001). In multivariate analysis, 7/8 BM vs UCB had similar GRFS (hazard ratio [HR], 1.12; 95% CI, 0.87-1.45; P = .39), CRFS (HR, 1.06; 95% CI, 0.82-1.38; P = .66), overall survival (HR, 1.07; 95% CI, 0.80-1.44; P = .66), and relapse (HR, 1.44; 95% CI, 1.03-2.02; P = .03). However, the 7/8 BM group had a significantly higher risk for grade III-IV aGVHD (HR, 1.70; 95% CI, 1.16-2.48; P = .006) compared with the UCB group. UCB and 7/8 BM groups had similar outcomes, as measured by GRFS and CRFS. However, given the higher risk for grade III-IV aGVHD, UCB might be preferred for patients lacking matched donors. © 2019 American Society of Hematology. All rights reserved
Fuzzy logic controller design for PUMA 560 robot manipulator
The dynamic model of the robot manipulator contain from equations, these equations are nonlinear and contained from variations parameters due to variations in load, friction, and disturbance. The conventional computed torque (PD and PID) controllers are not highly suitable for nonlinear, complex, time-variant systems with delay. In this paper, the fuzzy logic controllers (FLC) has been used because it is efficient tools for control of nonlinear and uncertain parameters systems. This paper aims to design a fuzzy logic controller for position control of a PUMA 560 robot manipulator. Based on simulation results we conclude that the performance of the fuzzy logic controller in term of position tracking error in case of disturbance or load is better than the conventional computed torque (PD-CTC and PID-CTC) controllers
The Role of Social Software in Shaping the Cultural Identity of Saudi Citizens from Their Point of View: Al-Jouf Region as A Model
The current research aimed to determine the impact of the social software in shaping the cultural identity of Saudi citizens at Al-Jouf region. The information explosion and technological development have led to an increase in the use of social software in Saudi society, which directs it to the importance of conducting research that works to reveal the reasons for this growing use and its impact in shaping the cultural identity of the community. Therefore, the researchers formulated the questionnaire to determine the role of social software in shaping the cultural identity, so that the questionnaire has been applied to a sample consisted of (572) of citizens of Al-Jouf region, (221) male and (351) female, (193) less than 20 years old, (252) from 20 to 40 years old, and (127) more than 40 years old. The results showed the research recommended the need to raise awareness of the importance of social software and its impact in shaping the cultural identity. With the importance of directing research towards the mechanisms of consolidating Arab and Islamic culture, with the design of specialized programs to consolidate the cultural identity among the youth in Saudi society
The impact of solvent characteristics on performance and process stability of printed carbon resistive materials
Carbon conductive pastes deposited by screen printing are used in many commercial applications including sensors, PCB, batteries, and PV, and as such represent an important value-added coating. An experimental investigation was carried out into the role of the solvent on the drying characteristics, conductivity, and process consistency in screen printed carbon pastes. Four materials with solvent boiling points between 166 and 219°C were deposited at film thickness between 6 and 16 μm, and the sheet resistance and film thickness were measured after successive passes through an industrial dryer operating with an air temperature of 155°C. Sheet resistances of 14 Ω/sq. were obtained with the thicker films while thinner films produced a sheet resistance of 46 Ω/sq. Thinner films achieved a stable resistivity within a 2.5-min residence time, while the thicker films required a residence time in excess of 12.5 min to achieve a stable resistivity. As well as prolonging drying times, the higher boiling point increased the resistivity of the cured film. It is postulated that the lower resistance of the faster drying materials is a result of film stressing increasing inter particle contact. Process models indicate that multiple thin layers are a more efficient means of manufacture for the process parameters examined
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