1,009 research outputs found

    UK export performance research - review and implications

    Get PDF
    Previous research on export performance has been criticized for being a mosaic of autonomous endeavours and for a lack of theoretical development. Building upon extant models of export performance, and a review and analysis of research on export performance in the UK for the period 1990-2005, an integrated model of export performance is developed and theoretical explanations of export performance are put forward. It is suggested that a multi-theory approach to explaining export performance is viable. Management and policy implications for the UK emerging from the review and synthesis of the literature and the integrated model are discussed

    Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

    Get PDF
    Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality. Studies of rare human disorders of puberty and animal models point to a complex hypothalamic-pituitary-hormonal regulation, but the mechanisms that determine pubertal timing and underlie its links to disease risk remain unclear. Here, using genome-wide and custom-genotyping arrays in up to 182,416 women of European descent from 57 studies, we found robust evidence (P < 5 × 10(-8)) for 123 signals at 106 genomic loci associated with age at menarche. Many loci were associated with other pubertal traits in both sexes, and there was substantial overlap with genes implicated in body mass index and various diseases, including rare disorders of puberty. Menarche signals were enriched in imprinted regions, with three loci (DLK1-WDR25, MKRN3-MAGEL2 and KCNK9) demonstrating parent-of-origin-specific associations concordant with known parental expression patterns. Pathway analyses implicated nuclear hormone receptors, particularly retinoic acid and γ-aminobutyric acid-B2 receptor signalling, among novel mechanisms that regulate pubertal timing in humans. Our findings suggest a genetic architecture involving at least hundreds of common variants in the coordinated timing of the pubertal transition

    A Multi-Sensor Exportable Approach for Automatic Flooded Areas Detection and Monitoring by a Composite Satellite Constellation

    Get PDF
    Timely and frequently updated information about flood-affected areas and their space-time evolution are often crucial in order to correctly manage the emergency phases. In such a context, optical data provided by meteorological satellites, offering the highest available temporal resolution (from hours to minutes), could have a great potential. As cloud cover often occurs reducing the number of usable optical satellite images, an appropriate integration of observations coming from different satellite systems will surely improve the probability to find cloud-free images over the investigated region. To make this integration effective, appropriate satellite data analysis methodologies, suitable for providing congruent results, regardless of the used sensor, are envisaged. In this paper, a sensor-independent approach (RST, Robust Satellites Techniques-FLOOD) is presented and applied to data acquired by two different satellite systems (Advanced Very High Resolution Radiometer (AVHRR) onboard National Oceanic and Atmospheric Administration platforms and Moderate Resolution Imaging Spectroradiometer (MODIS) onboard Earth Observing System satellites) at different spatial resolutions (from 1 km to 250 m) in the case of Elbe flood event occurred in Germany on August 2002. Results achieved demonstrated as the full integration of AVHRR and MODIS RST-FLOOD products allowed us to double the number of satellite passes daily available, improving continuity of monitoring over flood-affected regions. In addition, the application of RST-FLOOD to higher spatial resolution MODIS (250 m) data revealed to be crucial not only for mapping purposes but also for improving RST-FLOOD capability in identifying flooded areas not previously detected at lower spatial resolution

    Self-assembled nanogel made of mannan : synthesis and characterization

    Get PDF
    Amphiphilic mannan (mannan-C16) was synthesized by the Michael addition of hydrophobic 1-hexadecanethiol (C16) to hydroxyethyl methacrylated mannan (mannan-HEMA). Mannan-C16 formed nanosized aggregates in water by selfassembly via the hydrophobic interaction among C16molecules as confirmed by hydrogen nuclearmagnetic resonance (1H NMR), fluorescence spectroscopy, cryo-field emission scanning electron microscopy (cryo-FESEM), and dynamic light scattering (DLS). The mannan-C16 critical aggregation concentration (cac), calculated by fluorescence spectroscopy with Nile red and pyrene, ranged between 0.04 and 0.02mg/mL depending on the polymer degree of substitution ofC16 relative to methacrylated groups. Cryo-FESEM micrographs revealed that mannan-C16 formed irregular spherical macromolecular micelles, in this work designated as nanogels, with diameters ranging between 100 and 500 nm. The influence of the polymer degree of substitution, DSHEMA andDSC16, on the nanogel size and zeta potential was studied byDLS at different pH values and ionic strength and as a function of mannan-C16 and urea concentrations. Under all tested conditions, the nanogel was negatively charged with a zeta potential close to zero. Mannan-C16 with higher DSHEMA and DSC16 values formed larger nanogels andwere also less stable over a 6month storage period and at concentrations close to the cac.When exposed to solutions of different pH and aggressive conditions of ionic strength and urea concentration, the size of mannan-C16 varied to some extent but was always in the nanoscale range.International Iberian Nanotechnology Laboratory (INL)Fundação para a Ciência e a Tecnologia (FCT

    Integration of optical and passive microwave satellite data for flooded area detection and monitoring

    Get PDF
    Flooding represents a serious threat to millions of people around the world and its hazard is rising as a result of climate changes. From this perspective, flood risk management is a key focus of many governments, whose priority is to have frequently updated and accurate information about the flood state and evolution to promptly react to the disaster and to put in place effective countermeasures devoted to limit damages and human lives losses. Remote sensing technology allows for flood monitoring at different spatial and temporal resolutions with an adequate level of accuracy. In particular, for emergency response purposes, an integrated use of satellite data, acquired by both optical and passive or active microwave instruments, has to be preferred to have more complete and frequently updated information on soil conditions and to better support decision makers. In this framework, multi-year time series of MODIS (Moderate Resolution Imaging Spectroradiometer) and AMSR-E (Advanced Microwave Scanning Radiometer for Earth Observing System) data were processed and analyzed. In detail, the Robust Satellite Techniques (RST), a multi-sensor approach for satellite data analysis, has been implemented for studying the August 2002 Elbe river flood occurred in Germany, trying to assess the potential of such an integrated system for the determination of soil status and conditions (i.e. moisture variation, water presence) as well as for a timely detection and a near real time monitoring of critical soil conditions

    The international entrepreneurial firm's social networks

    Get PDF
    This paper investigates theoretically the importance and impact of the international entrepreneurial firms’ (IEFs) social networks on selected firms’ strategies. We focus specifically on some core attributes of IEFs and the impact of social networks on such strategies as the choice of the foreign markets to operate and the foreign entry modes. The social networks are a major driver of the internationalization from inception and help in overcoming a variety of physical and social resource limitations as well as transactional hazards. We conclude that it is likely that both some fundamental characteristics of the IEFs and those of the foreign markets entered account for these firms reliance on their social networks

    Policy drivers of international entrepreneurship in Europe

    Full text link
    The diversity of countries and cultures in Europe necessitates an international outlook for most businesses. This paper examines the internationalisation of business in Europe through a literature review on international entrepreneurship theory. The role of the individual business owner and of business and interorganisational activity in facilitating the internationalisation of businesses in Europe is discussed by utilising the theoretical framework of international entrepreneurship and by putting forward three main propositions. The main aim and intent of this paper is to understand how the policies of individual governments and institutions such as the European Union help businesses in Europe to internationalise, with particular emphasis on businesses in the Baltic region. The paper discusses policy implications and suggestions for future research, which highlight the importance for firms in Europe of focussing on international markets.<br /

    Functional design of distributed-power freight trains: Simulation of operation on the Turin-Savona railway line

    Get PDF
    This paper presents an in-depth investigation of the engineering aspects related to the design and operation of distributed-power freight trains (F-EMU, freight - Electric Multiple Unit), and their potential advantages, by evaluating the various components of this new kind of train and comparing its performance with a traditional freight train. Electric motors, distributed along certain motorised carriages of connected wagons, allow, among others, the power necessary to avoid multiple locomotives, used on traditional lines for the heaviest trains, to be supplied, and access to high-speed lines, which were originally designed and constructed - in Italy for example - for mixed use (i.e. for passengers and freight). Interesting speed levels (140- 160 km/h) could be achieved, subject to the other requirements of the rolling stock, which are indicated later on in the paper. EMU trains are known to be used for passenger services, as they allow high speeds to be reached, energy to be recuperated during braking and, in general, increases in the performances of the rolling stock to be obtained. Analyses of the operation of freight trains have pointed out that distributed-power trains are able to reach appreciable acceleration values, during traction, because of a better distribution of the adhesive weight. High performances can be achieved, during the braking phase, when electro-dynamic braking, which allows energy to be recovered, is adopted together with a dominant electro-pneumatic braking system: this also prevents the infrastructure operator from having to lengthen the block sections to allow any poorly-braking 700-750 m long traditional trains to transit. The use of such innovative freight trains also satisfies the modern requirements of intermodal transport: electrification of the whole train makes it possible to transport units of refrigerated goods and perishable goods, and to conduct a constant monitoring of the load. After having examined the design and functional requirements of the F-EMU train and a traditional one, a comparison is made of the performances of a distributedpower freight train and a conventional one, on the Turin- Savona railway line, through the use of a micro-simulating software package that is able to reproduce the railway operations along the considered stretch and saturate the current passenger timetable with freight trains. From the results, it has emerged that the adoption of distributed-power freight trains leads to a marked reduction of the travel times and an increase in the intermodal transport units (UTI) that can be transported over the reference time frame, especially when considering the use of 750 m long trains
    corecore