826 research outputs found
A new cosmological model with quadratic expansion
We present a new cosmological model capable of reproducing late-time
acceleration, i.e. by supporting certain parametrization of the Hubble parameter. By using
observational data from Hubble, Pantheon, and Baryonic Acoustic Oscillations
(BAO) dataset, we investigate the constraints on the proposed quadratic Hubble
parameter . This proposal caused the Universe to transition from its
decelerated phase to its accelerated phase. Further, the current constrained
value of the deceleration parameter from the combined Hubble+Pantheon+BAO
dataset is , which indicates that the Universe is
accelerating. We also analyze the evolution of energy density, pressure, and
EoS parameters to infer the Universe's accelerating behavior. Finally, we use a
stability analysis with linear perturbations to assure the model's stability.Comment: Physics of the Dark Universe published versio
A New Diagnostic of Dark Energy in General Relativity Theory
In this paper, we propose a new parametrization of dark energy based on the
diagnostic tool behavior. For this purpose, we investigate a functional
form of the that predicts the popular dark energy dynamical models,
namely phantom and quintessence. We also found the famous cosmological constant
for specified values of the model's parameters. We employed the Markov Chain
Monte Carlo approach to constrain the cosmological model using Hubble, Pantheon
samples, and BAO datasets. Finally, we used observational constraints to
investigate the characteristics of dark energy evolution and compare our
findings to cosmological predictions.Comment: The European Physical Journal C accepted versio
Traditional handloom practices of Nyishi tribe of Arunachal Pradesh, Eastern Himalaya
442-449The documentation of traditional handloom practices of Nyishi tribe and their cultural attire was done in Papum pare district of Arunachal Pradesh wherein 7 selected villages were surveyed during May 2018 to February 2019 through random sampling with semi-structured questionnaire. Rubung Ruekio, a traditional loin loom of Nyishi tribe is prepared from locally available resources, viz., Bambusa. tulda, B. pallida, Dendrocalamus hamiltonii, Gmelina arborea, Michelia species and Terminalia myriocarpa. Most of the weavers were female and weaved culturally important traditional dresses such as Pomo gale, Dumping gale, Jekum/Name-acham gale, Jinjab gale, Juhu/Junghang gale and Luch/lungch gale which are worn especially during auspicious occasions. Of these, Jekum gale, Pomo gale and Dumping gale culturally significant. The market price of gale varied tremendously depending on type of raw material and type of handloom used in the production
Traditional handloom practices of Nyishi tribe of Arunachal Pradesh, Eastern Himalaya
The documentation of traditional handloom practices of Nyishi tribe and their cultural attire was done in Papum pare district of Arunachal Pradesh wherein 7 selected villages were surveyed during May 2018 to February 2019 through random sampling with semi-structured questionnaire. Rubung Ruekio, a traditional loin loom of Nyishi tribe is prepared from locally available resources, viz., Bambusa. tulda, B. pallida, Dendrocalamus hamiltonii, Gmelina arborea, Michelia species and Terminalia myriocarpa. Most of the weavers were female and weaved culturally important traditional dresses such as Pomo gale, Dumping gale, Jekum/Name-acham gale, Jinjab gale, Juhu/Junghang gale and Luch/lungch gale which are worn especially during auspicious occasions. Of these, Jekum gale, Pomo gale and Dumping gale culturally significant. The market price of gale varied tremendously depending on type of raw material and type of handloom used in the production
Implications of the outcome of EMPA-REG outcome on type 2 diabetes mellitus management
Diabetes has been implicated in micro-and macro-vascular complications. Glycaemic controls have been found to reduce the risk of microvascular complications in type 2 diabetes. However, studies suggest a possible relation between glycaemic control in decreasing macrovascular complications. The traditional approach of aggressive glycaemic management often leads to hypoglycaemia. Hypoglycaemia induces a series of physiological effects that increase cardiovascular disease risk (CVD). In fact, most of the hypoglycaemic agents such as thiazolidinediones, sulfonylureas, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodium-glucose cotransporter 2 (SGLT2) inhibitors have been approved based on their ability to decrease glycosylated haemoglobin A1c (HbA1c) rather than their ability to prevent CV morbidity and mortality. In the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients Removing Excess Glucose (EMPA-REG OUTCOME®) trial, Empagliflozin, a sodium-glucose co-transporter-2 (SGLT2) inhibitor, have been proven to exert a cardioprotective effect in type 2 diabetes patients. This paper discusses the outcome of EMPA-REG OUTCOME® and its implication in the management of type 2 diabetes patients that are at risk for CVD
Rediscovery of Impatiens khasiana Hook.f. after more than a century
Impatiens khasiana Hook.f. (Balsaminaceae) has been rediscovered after a period of 129 years from Meghalaya, in north-eastern India.
A detailed description from living specimens, coloured photographs and other relevant information are provided for easy identification. The name I. khasiana Hook.f. is here lectotypified
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An investigation of Agriculture Knowledge Sharing through Indigenous Communication Systems: Insights from Ethnic Communities
Developing countries like India are having latest methods of communication, but their effective utilization by people who are less exposed is doubtful. In rural areas indigenous means of communication still play a vital role in social functioning, maintenance and social change. A study was employed with a qualitative research design to explore the indigenous communication systems of four ethnic communities (Ahom, Kachari, Mising and Deori) in Dhemaji district of Assam. The total respondents for the study was one hundred (100) comprising both male and female to capture gender-specific roles in agricultural communication. Focus group discussions, interviews, and auto-ethnographic observations were employed, ensuring a participatory approach to collect data from four selected villages across two culturally diverse blocks. Findings reveal that folk songs such as Bihu songs, Oi-nitom, and Bisugeet encapsulate agricultural processes and seasonal transitions, ensuring the preservation and transmission of traditional knowledge. The rituals like Narasiga Sabah, Nakathia Sisha, and Guch Luwa not only serve as cultural markers but also communicate critical agricultural practices to farmers. Similarly, proverbs and riddles acted as mnemonic devices for agricultural techniques and ecological wisdom. The study concludes that integrating these indigenous practices with modern extension systems can significantly enhance rural communication strategies. The findings of the present study hold a great potential in the field of communication for development research as well as for planning and dissemination of need based information among rural families for agricultural development that elevate sustainable rural livelihoods
Structure–activity study of N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a bitopic ligand that acts as a negative allosteric modulator of the dopamine D2 receptor
We recently demonstrated that SB269652 (1) engages one protomer of a dopamine D2 receptor (D2R) dimer in a bitopic mode to allosterically inhibit the binding of dopamine at the other protomer. Herein, we investigate structural deter- minants for allostery, focusing on modifications to three moieties within 1. We find that orthosteric “head” groups with small 7-substituents were important to maintain the limited negative cooperativity of analogues of 1, and replacement of the tetrahydroisoquinoline head group with other D2R “privileged structures” generated orthosteric antagonists. Additionally, replacement of the cyclohexylene linker with polymethylene chains conferred linker length dependency in allosteric pharma- cology. We validated the importance of the indolic NH as a hydrogen bond donor moiety for maintaining allostery. Replacement of the indole ring with azaindole conferred a 30-fold increase in affinity while maintaining negative cooperativity. Combined, these results provide novel SAR insight for bitopic ligands that act as negative allosteric modulators of the D2R
Attenuation of coda waves in the Northeastern Region of India
Coda wave attenuation quality factor
Qc is estimated in the northeastern region of India
using 45 local earthquakes recorded by regional
seismic network. The quality factor Qc was estimated
using the single backscattering model modified
by Sato (J Phys Earth 25:27–41, 1977), in
the frequency range 1–18 Hz. The attenuation and
frequency dependence for different paths and the
correlation of the results with geotectonics of the
region are described in this paper. A total of 3,890
Qc measurements covering 187 varying paths are
made for different lapse time window of 20, 30, 40,
50, 60, 70, 80, and 90 s in coda wave. The magnitudes
of the analyzed events range from 1.2 to 3.9
and focal depths range between 7 and 38 km. The
source–receiver distances of the selected events
range between 16 and 270 km. For 30-s duration,
the mean values of the estimated Qc vary from
50 ± 12 (at 1 Hz) to 2,078 ± 211(at 18 Hz) for the Arunachal Himalaya, 49 ± 14 (at 1 Hz) to
2,466 ± 197 (at 18 Hz) for the Indo-Burman, and
45 ± 13 (at 1 Hz) to 2,069 ± 198 (at 18 Hz) for
Shillong group of earthquakes. It is observed
that Qc increases with frequency portraying
an average attenuation relation Qc = 52.315 ±
1.07 f (1.32±0.036) for the region. Moreover, the pattern
of Qc−1 with frequency is analogous to the
estimates obtained in other tectonic areas in the
world, except with the observation that the Qc−1
is much higher at 1Hz for the northeastern region.
The Qc−1 is about 10−1.8 at 1 Hz and decreases to
about 10−3.6 at 18 Hz indicating clear frequency
dependence. Pertaining to the spatial distribution
of Qc values, Mikir Hills and western part
of Shillong Plateau are characterized by lower
attenuation
Attenuation of coda waves in the Northeastern Region of India
Coda wave attenuation quality factor
Qc is estimated in the northeastern region of India
using 45 local earthquakes recorded by regional
seismic network. The quality factor Qc was estimated
using the single backscattering model modified
by Sato (J Phys Earth 25:27–41, 1977), in
the frequency range 1–18 Hz. The attenuation and
frequency dependence for different paths and the
correlation of the results with geotectonics of the
region are described in this paper. A total of 3,890
Qc measurements covering 187 varying paths are
made for different lapse time window of 20, 30, 40,
50, 60, 70, 80, and 90 s in coda wave. The magnitudes
of the analyzed events range from 1.2 to 3.9
and focal depths range between 7 and 38 km. The
source–receiver distances of the selected events
range between 16 and 270 km. For 30-s duration,
the mean values of the estimated Qc vary from
50 ± 12 (at 1 Hz) to 2,078 ± 211(at 18 Hz) for the Arunachal Himalaya, 49 ± 14 (at 1 Hz) to
2,466 ± 197 (at 18 Hz) for the Indo-Burman, and
45 ± 13 (at 1 Hz) to 2,069 ± 198 (at 18 Hz) for
Shillong group of earthquakes. It is observed
that Qc increases with frequency portraying
an average attenuation relation Qc = 52.315 ±
1.07 f (1.32±0.036) for the region. Moreover, the pattern
of Qc−1 with frequency is analogous to the
estimates obtained in other tectonic areas in the
world, except with the observation that the Qc−1
is much higher at 1Hz for the northeastern region.
The Qc−1 is about 10−1.8 at 1 Hz and decreases to
about 10−3.6 at 18 Hz indicating clear frequency
dependence. Pertaining to the spatial distribution
of Qc values, Mikir Hills and western part
of Shillong Plateau are characterized by lower
attenuation
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