276 research outputs found
African Water: Supporting African involvement in the EU Framework Programme.
Water researchers in developing countries have yet to take full advantage of the funding and collaborative research opportunities presented by the EU Framework Programme. There are a variety of reasons for this, such as insufficient information and a lack of previous experience. The African Water initiative aims to increase the involvement of African water researchers through a range of activities including communication and dissemination, capacity building and development, and complementary initiatives. The project has demonstrated that there is a demand for such sector-specific support activities. However, African Water is a small component of a much larger process of partnership between the developed and the less-developed countries of the world, involving many different European and African organisations working across political, institutional and technical domains, and complementing the wide range of actions already being undertaken
Wet Etching and Surface Analysis of Chemically Treated InGaN Films
This paper discusses the performance of different wet chemical etchants on InGaN. It is shown that certain etchants can be used to chemically etch and remove appreciable amounts of InGaN even though the etch rate is not as high as observed for other III-V materials. The performance of etchants studied here were (i) two different ratios of HF, HNO3, (ii) cyclic usage of NH4OH followed
by HCl, (iii) hot H2SO4 and H3PO4 mixture, and (iv) conc. NH4OH. The etched surfaces have then been analyzed by x-ray
photoelectron spectroscopy (XPS). Different etch residues were observed on the top surface. These results suggest an alternative to reactive plasma etching or photo-enhanced electrochemical etching of InGaN type materials. Based on the observed performance of the etchants studied, it was also possible to segregate the surface cleaning protocols and etchants
A Methodology to Inter-Compare Brass and Such Alloys Manufactured at Different Geographical Locations
319-329This paper is about a method developed to normalize the Time of Flight Secondary Ion Mass Spectrometry (TOF-SIMS) data counts of each constituent ion in a mass spectra, by dividing each ion count with the total ion count. So by comparing their statistical means, data of different samples of any alloy like brass etc. from different places around the world can be inter-compared using TOF-SIMS data collected using similar separate instruments under similar experimental conditions. Such a methodology can also be extended to analysis of constituents of other materials using TOF-SIMS as well. Here, all brass samples were chosen on a representative global basis and had similar end uses. Variations in normalized mean counts of major constituent ions suggest that brass produced in different parts of the world for similar uses can be a little different in composition and can be readily identified and distinguished using their normalized statistical mean ion counts using TOF-SIMS. Their performance does not drastically change due to variation in such constituents of the alloy as the thermal treatments used on them were possibly different. Based on these observations, it was felt that unless there is a drastic change in any alloys’ micro-structure or crystalline phase properties, there will be no drastic change in its properties with variation of its’ major or minor alloying constituents. Data from literature using different aluminum alloys as a representative example and using their available data on micro-hardness and noting their variation with alloying also suggests such a phenomena
A Methodology to Inter-Compare Brass and Such Alloys Manufactured at Different Geographical Locations
This paper is about a method developed to normalize the Time of Flight Secondary Ion Mass Spectrometry (TOF-SIMS) data counts of each constituent ion in a mass spectra, by dividing each ion count with the total ion count. So by comparing their statistical means, data of different samples of any alloy like brass etc. from different places around the world can be inter-compared using TOF-SIMS data collected using similar separate instruments under similar experimental conditions. Such a methodology can also be extended to analysis of constituents of other materials using TOF-SIMS as well. Here, all brass samples were chosen on a representative global basis and had similar end uses. Variations in normalized mean counts of major constituent ions suggest that brass produced in different parts of the world for similar uses can be a little different in composition and can be readily identified and distinguished using their normalized statistical mean ion counts using TOF-SIMS. Their performance does not drastically change due to variation in such constituents of the alloy as the thermal treatments used on them were possibly different. Based on these observations, it was felt that unless there is a drastic change in any alloys’ micro-structure or crystalline phase properties, there will be no drastic change in its properties with variation of its’ major or minor alloying constituents. Data from literature using different aluminum alloys as a representative example and using their available data on micro-hardness and noting their variation with alloying also suggests such a phenomen
Infrastructure for Detector Research and Development towards the International Linear Collider
The EUDET-project was launched to create an infrastructure for developing and
testing new and advanced detector technologies to be used at a future linear
collider. The aim was to make possible experimentation and analysis of data for
institutes, which otherwise could not be realized due to lack of resources. The
infrastructure comprised an analysis and software network, and instrumentation
infrastructures for tracking detectors as well as for calorimetry.Comment: 54 pages, 48 picture
Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
Background
Prostate cancer (PrCa) demonstrates a heterogeneous clinical presentation ranging from largely indolent to lethal. We sought to identify a signature of rare inherited variants that distinguishes between these two extreme phenotypes.
Methods
We sequenced germline whole exomes from 139 aggressive (metastatic, age of diagnosis < 60) and 141 non-aggressive (low clinical grade, age of diagnosis ≥60) PrCa cases. We conducted rare variant association analyses at gene and gene set levels using SKAT and Bayesian risk index techniques. GO term enrichment analysis was performed for genes with the highest differential burden of rare disruptive variants.
Results
Protein truncating variants (PTVs) in specific DNA repair genes were significantly overrepresented among patients with the aggressive phenotype, with BRCA2, ATM and NBN the most frequently mutated genes. Differential burden of rare variants was identified between metastatic and non-aggressive cases for several genes implicated in angiogenesis, conferring both deleterious and protective effects.
Conclusions
Inherited PTVs in several DNA repair genes distinguish aggressive from non-aggressive PrCa cases. Furthermore, inherited variants in genes with roles in angiogenesis may be potential predictors for risk of metastases. If validated in a larger dataset, these findings have potential for future clinical application
Comparison of Cheap Imported Stainless Steel Samples with Indian-made Samples and a Crystalline Phase Based Methodology for Bench-marking them
455-463In the emerging South Asian markets, from the commercial as well as engineering point of view, performance and quality of any local engineering product like steel structures vis a vis similar but imported, cheap materials is always an issue. In this paper, as a representative case, we discuss the composition, crystalline phase and microstructure of two most common stainless steel grades manufactured locally by the major government of India sponsored (GOIS) Steel maker and compare them with similar cheap imported items that some local private businesses prefer due to slightly lower costs but having similar materials usage parameters. We have also used wet etch based micrographic analysis to compare surface morphology and have also done composition analysis in our results. It is shown that even if ASTM standards of composition are followed, since their crystalline phase components are not the same, their performance and properties are never comparable. More stringent quality bench-marking of such alloy materials for checking repeatibility of batches and processes using X-ray diffraction and Raman spectral data analysis is thereby proposed
Energy Resolution Performance of the CMS Electromagnetic Calorimeter
The energy resolution performance of the CMS lead tungstate crystal electromagnetic calorimeter is presented. Measurements were made with an electron beam using a fully equipped supermodule of the calorimeter barrel. Results are given both for electrons incident on the centre of crystals and for electrons distributed uniformly over the calorimeter surface. The electron energy is reconstructed in matrices of 3 times 3 or 5 times 5 crystals centred on the crystal containing the maximum energy. Corrections for variations in the shower containment are applied in the case of uniform incidence. The resolution measured is consistent with the design goals
CMS physics technical design report : Addendum on high density QCD with heavy ions
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