Hillslope Asymmetry Maps Reveal Widespread, Multi-Scale Organization

Hillslope asymmetry is the condition in which oppositely-facing hillslopes within an area have differing average slope angles, and indicates aspect-related variability in hillslope evolution. As such, the presence, orientation and magnitude of asymmetry may be a useful diagnostic for understanding process dominance. We present a new method for quantifying and mapping the spatial distribution of hillslope asymmetry across large areas. Resulting maps for the American Cordillera of the Western Hemisphere and the western United States reveal that hillslope asymmetry is widespread, with distinct trends at continental to drainage scales. Spatial patterns of asymmetry correlate with latitude along the American Cordillera, mountain-range orientation for many ranges in the western United States, and elevation in the Idaho Batholith of the Northern Rocky Mountains. Spatial organization suggests that non-stochastic, process-driven controls cause these patterns. The hillslope asymmetry metric objectively captures previously-documented extents and frequencies of valley asymmetry for the Gabilan Mesa of the central California Coast Range. Broad-scale maps of hillslope asymmetry are of interest to a wide range of disciplines, as spatial patterns may reflect the influence of tectonics, atmospheric circulation, topoclimate, geomorphology, hydrology, soils and ecology on landscape evolution. These maps identify trends and regions of hillslope asymmetry, allow possible drivers to be spatially constrained, and facilitate the extrapolation of site-specific results to broader regions

Finding Our Fathers

We never considered how hard it was for our fathers to go to work every day, toiling away at a job they didn’t like. And even worse, seemingly having no other choices because their families were depending on them for their very existence. Growing up, our fathers did not have time for family; spending time with us was something remote from their daily life, making them a stranger in each of their perspective homes. Worse still, We were too young to understand why our fathers were not present. This essay reveals how we have attempted to make sense of the experience this distance between us and our fathers has caused in order to detoxify our individual images of our fathers. Detoxifying the image of father means recognizing that our fathers’ have been wounded as well.</p

Energy- and flux-budget (EFB) turbulence closure model for the stably stratified flows. Part I: Steady-state, homogeneous regimes

We propose a new turbulence closure model based on the budget equations for the key second moments: turbulent kinetic and potential energies: TKE and TPE (comprising the turbulent total energy: TTE = TKE + TPE) and vertical turbulent fluxes of momentum and buoyancy (proportional to potential temperature). Besides the concept of TTE, we take into account the non-gradient correction to the traditional buoyancy flux formulation. The proposed model grants the existence of turbulence at any gradient Richardson number, Ri. Instead of its critical value separating - as usually assumed - the turbulent and the laminar regimes, it reveals a transition interval, 0.1< Ri <1, which separates two regimes of essentially different nature but both turbulent: strong turbulence at Ri<<1; and weak turbulence, capable of transporting momentum but much less efficient in transporting heat, at Ri>1. Predictions from this model are consistent with available data from atmospheric and lab experiments, direct numerical simulation (DNS) and large-eddy simulation (LES).Comment: 40 pages, 6 figures, Boundary-layer Meteorology, resubmitted, revised versio

The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols

It has been previously proposed that nitric oxide (NO) is the only biologically relevant nitrogen oxide capable of activating the enzyme soluble guanylate cyclase (sGC). However, recent reports implicate HNO as another possible activator of sGC. Herein, we examine the affect of HNO donors on the activity of purified bovine lung sGC and find that, indeed, HNO is capable of activating this enzyme. Like NO, HNO activation appears to occur via interaction with the regulatory ferrous heme on sGC. Somewhat unexpectedly, HNO does not activate the ferric form of the enzyme. Finally, HNO-mediated cysteine thiol modification appears to also affect enzyme activity leading to inhibition. Thus, sGC activity can be regulated by HNO via interactions at both the regulatory heme and cysteine thiols

A Robust Quantile Huber Loss With Interpretable Parameter Adjustment In Distributional Reinforcement Learning

Distributional Reinforcement Learning (RL) estimates return distribution mainly by learning quantile values via minimizing the quantile Huber loss function, entailing a threshold parameter often selected heuristically or via hyperparameter search, which may not generalize well and can be suboptimal. This paper introduces a generalized quantile Huber loss function derived from Wasserstein distance (WD) calculation between Gaussian distributions, capturing noise in predicted (current) and target (Bellman-updated) quantile values. Compared to the classical quantile Huber loss, this innovative loss function enhances robustness against outliers. Notably, the classical Huber loss function can be seen as an approximation of our proposed loss, enabling parameter adjustment by approximating the amount of noise in the data during the learning process. Empirical tests on Atari games, a common application in distributional RL, and a recent hedging strategy using distributional RL, validate the effectiveness of our proposed loss function and its potential for parameter adjustments in distributional RL. The implementation of the proposed loss function is available here.Comment: 6 pages, 1 figure, to be published in ICASSP 202

Rugby sevens match demands and measurement of performance: A review

© 2018, University of Zagreb - Faculty of Kinesiology. All rights reserved. The purpose of this review is to summarize the research that has examined the match demands of elite-level, men’s rugby sevens, and provide enhanced understanding of the elements contributing to successful physical and technical performance. Forty-one studies were sourced from the electronic database of PubMed, Google Scholar and SPORTDiscus. From these, twelve original investigations were included in this review. Positive match outcomes are the result of an interplay of successful physical, technical, and tactical performances. The physical performance of players (activity profile measurement from GPS) includes high relative total distance and high-speed distance values in comparison to other team sports. The technical performance of players (skill involvement measurement from match statistics) involves the execution of a range of specific offensive and defensive skills to score points or prevent the opponent from scoring. The factors influencing change in these performance constructs has not been investigated in rugby sevens. There is a paucity in the literature surrounding the situational and individual factors affecting physical and skill performance in elite rugby sevens competition. Future studies should investigate the factors likely to have the strongest influence on player performance in rugby sevens. This should include larger sample sizes and account for repeated measures within players. This will allow coaches and scientists to improve their interpretation of activity and skill profile data, and make more informed decisions on players’ athletic preparation program

Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins

As a result of the adaptation of life to an aerobic environment, nature has evolved a panoply of metalloproteins for oxidative metabolism and protection against reactive oxygen species. Despite the diverse structures and functions of these proteins, they share common mechanistic grounds. An open-shell transition metal like iron or copper is employed to interact with O_2 and its derived intermediates such as hydrogen peroxide to afford a variety of metal–oxygen intermediates. These reactive intermediates, including metal-superoxo, -(hydro)peroxo, and high-valent metal–oxo species, are the basis for the various biological functions of O_2-utilizing metalloproteins. Collectively, these processes are called oxygen activation. Much of our understanding of the reactivity of these reactive intermediates has come from the study of heme-containing proteins and related metalloporphyrin compounds. These studies not only have deepened our understanding of various functions of heme proteins, such as O2 storage and transport, degradation of reactive oxygen species, redox signaling, and biological oxygenation, etc., but also have driven the development of bioinorganic chemistry and biomimetic catalysis. In this review, we survey the range of O_2 activation processes mediated by heme proteins and model compounds with a focus on recent progress in the characterization and reactivity of important iron–oxygen intermediates. Representative reactions initiated by these reactive intermediates as well as some context from prior decades will also be presented. We will discuss the fundamental mechanistic features of these transformations and delineate the underlying structural and electronic factors that contribute to the spectrum of reactivities that has been observed in nature as well as those that have been invented using these paradigms. Given the recent developments in biocatalysis for non-natural chemistries and the renaissance of radical chemistry in organic synthesis, we envision that new enzymatic and synthetic transformations will emerge based on the radical processes mediated by metalloproteins and their synthetic analogs

The State of Coral Reef Ecosystems of Southeast Florida

The northern extension of the Florida reef tract and a complex of limestone ridges run parallel to the subtropical Atlantic coastline of southeast Florida. Spanning 170 km from the northern border of Biscayne National Park (BNP) in Miami-Dade County to the St. Lucie Inlet in Martin County, the reefs and hardbottom areas in this region support a rich and diverse biological community (Figure 5.1). Nearshore reef habitats in southeast Florida include hardbottom areas, patch reefs and worm reefs (Phragmatopoma spp.) exhibiting abundant octocoral, macroalgae, stony coral and sponge assemblages. Offshore, coral reef associated biotic assemblages occur on linear Holocene Acropora palmata mid-shelf and shelf margin reefs that extend from Miami Dade County to Palm Beach County (Lighty, 1977; Figure 5.2). Anastasia Formation limestone ridges and terraces colonized by reef biota characterize the reefs from Palm Beach County to Martin County (Cooke and Mossom, 1929). The coastal region of southeast Florida is highly developed, containing one third of Florida’s population of 16 million people (U.S. Census Bureau, 2006). Many southeast Florida reefs are located just 1.5 km from this urbanized shoreline. Despite their unique position as the highest latitude reefs along the western Atlantic seaboard, the reefs of southeast Florida have only recently received limited scientific and resource management attention. Andrews et al. (2005) discussed the reefs of southeast Florida and the critical need to implement actions that fill resource knowledge gaps and address conservation and threats to reef health. This report further examines and updates the list of stressors imperiling the health of southeast Florida’s reefs, and presents information gained from new research, monitoring and management efforts to determine the extent and condition of reef resources in this distinctive region