754 research outputs found
THE ROLE OF HYBRID WORK MODELS IN ENHANCING EMPLOYEE WELL-BEING, PRODUCTIVITY, AND JOB SATISFACTION
Introduction: The hybrid workplace model, which combines in-office and remote work, has gained significant traction, particularly in the aftermath of the COVID-19 pandemic. This shift has introduced new dynamics in workplace flexibility, altering employee well-being, productivity, and job satisfaction. Understanding the impact of hybrid work is crucial as organizations adapt to evolving work environments.Objective: This study aims to investigate the relationship between hybrid work models and employee well-being, productivity, and job satisfaction. The study is guided by two hypotheses: (1) Hybrid work environments promote employee well-being, and (2) Hybrid work arrangements lead to increased productivity and job satisfaction.Methods: A comprehensive literature review was conducted to establish the theoretical foundation for the study. A survey was administered to 1,000 employees from organizations implementing hybrid work models. Regression and correlation analyses were performed on the collected data to assess the relationships between hybrid work arrangements, well-being, productivity, and job satisfaction.Results: The findings demonstrate a positive correlation between hybrid work models and employee well-being, confirming the first hypothesis. Employees in hybrid roles reported better mental health and job satisfaction. Additionally, the study supports the second hypothesis, as higher productivity was observed among employees with increased remote work flexibility.Conclusion: Hybrid work models can serve as an effective strategy for improving organizational success and employee satisfaction. When properly implemented, they enhance worker well-being, increase productivity, and foster a more balanced work environment. Organizations should consider structured hybrid policies to maximize the benefits of this evolving work model in the modern workforce
Nω –CLOSED SETS IN NEUTROSOPHIC TOPOLOGICAL SPACES
Neutrosophic set and Neutrosophic Topological spaces has been introduced by Salama. Neutrosophic Closed set and Neutrosophic Continuous Functions were introduced by Salama et. al.. In this paper, we introduce the concept of Nω- closed sets and their properties in Neutrosophic topological spaces
Interval-valued intuitionistic fuzzy topological groups: Some properties
In this study, we introduce the concepts of interval-valued intuitionistic fuzzy group (abbreviated IVIFG), interval-valued intuitionistic fuzzy topological group (abbreviated IVIFTG), and interval-valued intuitionistic fuzzy product topology (abbreviated IVIFPT). We delve into the fundamental features of IVIFG, IVIFTG, and IVIFPT in further detail. The characterization of IVIFG and IVIFTG is examined using the concepts of interval-valued intuitionistic fuzzy continuous (abbreviated as IVIF-continuous) and interval-valued intuitionistic fuzzy relatively continuous (abbreviated as IVIF-relatively continuous)
Formulation of Sodium Alginate Nanospheres Containing Amphotericin B for the Treatment of Systemic Candidiasis
Purpose: The aim of this work was to formulate sodium alginate nanospheres of amphotericin B by controlled gellification method and to evaluate the role of the nanospheres as a “passive carrier” in targeted antifungal therapy.
Methods: Sodium alginate nanospheres of amphotericin B were prepared by controlled gellification method, and the particle size analysis was carried out by scanning electron microscopy. The carrier capacity of sodium alginate was evaluated in terms of drug to polymer ratio. In vitro release study was carried out on all drug loaded nanospheres by the dialysis method. Release kinetics of drug from different drug loaded nanospheres was also determined. The in vivo antifungal efficacy of nanospheres bound drug vis-à-vis the free drug was evaluated in candidiasis- induced mice models.
Results: Preparation of nanospheres through controlled gellification method yielded particles with a size range of 419.6 ± 0.28 nm. Studies on drug to polymer ratio showed a linear relationship between concentration of drug and drug loading capacity. In vitro release kinetic study revealed that the release of drug from the nanospheres followed Fickian diffusion. In vivo studies showed that the nanosphere-bound drug produced a higher antifungal efficacy than the free drug.
Conclusion: The formulated sodium alginate nanospheres containing amphotericin B was found to have better antifungal activity when compared to the free drug and also yielded sustained in vitro release.
Keywords: Nanospheres, sodium alginate, amphotericin B, controlled gellification method, in vitro & in vivo release > Tropical Journal of Pharmaceutical Research Vol. 6 (1) 2007: pp. 653-65
Science and Religion in the Context of Modern Society
The 1921 Physics Nobel Prize Winner, Albert Einstein in his 1941 “Science and Religion” expressed that “Science without religion is lame, religion without science is blind”. His deep conviction and concern for “religion and God” also have been expressed in his obituary issue of New York Times of April 15, 1955 thus: “My religion consists of a humble admiration of the illimitable superior spirit Who reveals Himself in the slight details we are able to perceive with our frail and feeble minds. That deeply emotional conviction of the presence of Superior Reasoning Power, which is revealed in the Incomprehensible Universe, forms my idea of God.
Development and in-vitro Evaluation of a Topical Drug Delivery System Containing Betamethazone Loaded Ethyl Cellulose Nanospheres
Purpose: Lipid nanospheres are used for the passive targeting of cosmetic agents to skin, thereby achieving major benefits such as reduction of total dose and avoidance of systemic absorption. The present study was carried out to exploit the feasibility of using polymeric nanospheres as an alternative and cheaper carrier for targeting corticosteroids to the skin.
Methods: Nanospheres were prepared from ethyl cellulose by a modified method of desolvation and cross linking. The drug betamethazone was incorporated into nanospheres and the drug: polymer ratio was evaluated to determine the carrier capacity of the polymer. In-vitro release studies of drug-loaded nanospheres were carried out by the centrifugal ultrafiltration method. The kinetics of release was determined and fitted to an empirical equation. The release of drug from drug-loaded nanospheres dispersing in a conventional cream was evaluated. A comparative in-vitro diffusion study was carried out between a commercial brand of cream and the cream incorporating nanospheres.
Results: Formulation of nanospheres of betamethazone by a modified method produced discrete particles. Studies on drug:polymer ratio showed a linear relationship between drug concentration and percentage of loading. The in-vitro release of drug-loaded nanospheres was found to be first order. The comparative in-vitro diffusion study between the commercial cream and the formulated cream showed a marked reduction in release rate from nanospheres-bound cream.
Conclusion: Formulated topical cream containing nanospheres of betamethazone was found to be a potential dermal delivery system for sustaining the release of the drug.
Keywords: Nanospheres, desolvation and cross-linking method, ethyl cellulose, betamethazone, in-vitro diffusion studies.> Tropical Journal of Pharmaceutical Research Vol. 4 (2) 2005: pp. 495-50
A Collaborative Ambient Picture Selection System Based on Layered Attention
One of the most immediately noticeable advantages of one-on-one communication as of late is the creation of picture-based, easygoing affiliations. Those daily monster photo swaps learning about customers' tastes in user-generated images and influencing recommendations has developed into a pressing need. It's true that several mixed models have been offered to combine client thing documented lead with various types of ancillary data (like image visual delineation or social connection) to better execute suggestions. Despite this, the past evaluations fail to capture the amazing views that influence clients' propensities in a bound together structure due to the remarkable characteristics of the client-conveyed images in social picture composes. Furthermore, the vast majority of these hybrid models relied on predetermined stacks to combine different types of data, which, according to the guidelines, admitted faulty proposal execution. In this study, we do just that by constructing a robust model of ideas for putting out socially critical pictures. We see three key focuses (i.e., move history, social impact, and proprietor venerate) that effect every client's dormant preferences, where each perspective outlines a canny factor from the eccentric relationship between customers and pictures, despite the fact that essential apathetic client enthusiasm appears in the standard framework factorization based proposition
Wind Integrated Thermal Unit Commitment Solution Using Grey Wolf Optimizer
The augment of ecological shield and the progressive exhaustion of traditional fossil energy sources have increased the interests in integrating renewable energy sources into existing power system. Wind power is becoming worldwide a significant component of the power generation portfolio. Profuse literature have been reported for the thermal Unit Commitment (UC) solution. In this work, the UC problem has been formulated by integrating wind power generators along with thermal power system. The Wind Generator Integrated UC (WGIUC) problem is more complex in nature, that necessitates a promising optimization tool. Hence, the modern bio-inspired algorithm namely, Grey Wolf Optimization (GWO) algorithm has been chosen as the main optimization tool and real coded scheme has been incorporated to handle the operational constraints. The standard test systems are used to validate the potential of the GWO algorithm. Moreover, the ramp rate limits are also included in the mathematical WGIUC formulation. The simulation results prove that the intended algorithm has the capability of obtaining economical resolutions with good solution quality
Awareness on antibiotic usage among undergraduate medical students in a teaching hospital, Guntur
Background: Antibiotics are the mainstay treatment of most of the infectious diseases. Inappropriate and irrational use of antimicrobial agents has led to increase in the development of antimicrobial resistance. Medical students are a part of health care system and they must be aware of increasing antibiotic resistance as they are the future prescribers. The objectives of the study were to assess the awareness on antibiotic usage and its resistance among medical students and to study the perception on antibiotic medication among medical students.Methods: This was a cross-sectional, semi-structured questionnaire-based study. Questionnaire consists of 4 parts- socio-demographic details, awareness on antibiotics and its resistance, knowledge on specific treatment of a disease, perception levels. Prior IEC approval was taken. The obtained data was statistically analyzed using Microsoft excel sheet.Results: Among 230 participants, majority of the students have awareness on general antibiotic usage and 97.8% were having knowledge about antibiotic resistance. The main source of information on antibiotic resistance is identified as classroom teaching (67.8%). 46.9% and 25.2% students correctly identified the drug of choice for treating enteric fever and community acquired pneumonia respectively.Conclusions: Degrees of awareness on antibiotics and its resistance is found to be good. Antibiotic usage pattern is not on par with knowledge. Knowledge on specific treatment of infectious disease is found to be less. So, antibiotic teaching should be integrated with clinical subjects
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