Multi-access drug delivery network and stability

A novel design of a multi-drug delivery network and diagnosis using a molecular network is proposed. By using a pair of tweezers to generate the intense optical vortices within the PANDA ring resonator, the required molecules (drug volumes) can be trapped and moved dynamically within the molecular bus networks, in which the required drug delivery targets can be achieved within the network. The advantage of the proposed system is that the diagnostic method can be used within a tiny system (thin film device or circuit), which is available as an embedded device for diagnostic use in patients. In practice, the large molecular networks such as ring, star, and bus networks can be integrated to form a large drug delivery system. The channel spacing of the trapped volumes (molecules) within the bus molecular networks can be provided by using the appropriate free spectrum range, which is analyzed and discussed in the terms of crosstalk effects. In this work, crosstalk effects of about 0.1% are noted, which can be neglected and does not affect the network stability

Proposal for Alzheimer’s diagnosis using molecular buffer and bus network

A novel design of an optical trapping tool for tangle protein (tau tangles, β-amyloid plaques) and molecular motor storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. In theory, the trapping force is formed by the combination between the gradient field and scattering photons, and is reviewed. By using the intense optical vortices generated within the PANDA ring resonator, the required molecular volumes can be trapped and moved dynamically within the molecular buffer and bus network. The tangle protein and molecular motor can transport and connect to the required destinations, enabling availability for Alzheimer’s diagnosis

Tunable and storage potential wells using microring resonator system for bio-cell trapping and delivery

In this work, we propose the technique that can be used to trap/delivery bio-cell by using the concept of dark solitons and potential well, in which the trapping force is formed by using the intense optical vortices generated within the series ring and the PANDA ring resonator, the microscopic bio-cell can be trapped and moved dynamically, in which the valley of the dark soliton is generated and controlled within the PANDA ring resonator by the control port signals

Gold nanoparticle trapping and delivery for therapeutic applications

A new optical trapping design to transport gold nanoparticles using a PANDA ring resonator system is proposed. Intense optical felds in the form of dark solitons controlled by Gaussian pulses are used to trap and transport nanoscopic volumes of matter to the desired destination via an optical waveguide. Theoretically, the gradient and scattering forces are responsible for this trapping phenomenon, where in practice such systems can be fabricated and a thin-film device formed on the specific artifcial medical materials, for instance, an artificial bone. The dynamic behavior of the tweezers can be tuned by controlling the optical pulse input power and parameters of the ring resonator system. Different trap sizes can be generated to trap different gold nanoparticles sizes, which is useful for gold nanoparticle therapy. In this paper, we have shown the utility of gold nanoparticle trapping and delivery for therapy, which may be useful for cosmetic therapy and related applications

The efficiency of mangosteen peel for dye removal

Abstract Mangosteen peel, an agricultural waste to be used as an adsorbent, was prepared by a simple and eco-friendly method. The dried mangosteen peel (DMP) was initially studied its surface charge by using the pH drift method. The adsorption experiments were performed using the batch technique to explore the efficiency of methylene blue (MB) removal. Fourier Transform Infrared (FTIR) spectroscopy and Field Emission Scanning Electron Microscopy (FE-SEM) were used to characterise the DMP before and after the adsorption process. The results revealed that MB could be adsorbed onto the DMP surface via the electrostatic interaction between the cationic dyes and surface functional groups of the DMP. To explore the MB adsorption efficiency of DMP adsorbent, the factors of the initial pH of MB solution, particle sizes of the DMP, DMP dosage, and contact time were investigated by using Ultraviolet-Visible (UV-Vis) spectrophotometer. It was found that the percentage of MB removal was 99.7% by using 5 g/L of DMP at particle sizes of lower than 75 μm within ten minutes under the initial pH condition of MB solution. Moreover, the experimental equilibrium adsorption data were fitted to the Freundlich isotherm model with R 2 = 0.9869.</jats:p

Drug Trapping and Delivery Using a PANDA Ring Resonator

AbstractWe propose a novel drug delivery system (DDS) by using a PANDA ring resonator to form and transmit and receive the microscopic volume by controlling some suitable ring parameters. The optical vortices (gradient optical field/well) can be generated and used to form the trapping tool in the same way as the optical tweezers. The microscopic volume (drug) can be trapped and moved (transported) dynamically within the wavelength router or network. In principle, the trapping force is formed by the combination between the gradient field and scattering photons, which has been reviewed. The advantage of the proposed system is that a transmitter and receiver can be formed within the same system, which is called transceiver, which is available for microscopic volume (drug volume) trapping and transportation (delivery)

Blood Circulation Network Incorporation an Artificial Bone for Real Time Operation

We propose the use of molecular buffers and networks for blood circulation in Haversian and Volkmanns canals to deliver the nutrient, drug and other essential substances in the regeneration process of bone and soft tissue. By using the dynamic optical tweezers generated within a PANDA ring resonator, the required molecules can be trapped and transported within the designed neural networks, in which the required substances can perform within the required region before reaching the required destinations. The advantage of the proposed system is that system, which can perform within the tiny system (thin film device). The system can be used to enhance the medical treatments, which can reduce the period of convalescence, i.e. operation, which means the in situ surgery can be realized. Furthermore, the transportation of the trapped molecule by light in the networks is described, the theoretical background is reviewed.</jats:p

Anatomical and physical properties of tendril perversion of Coccinia grandis (L.) Voigt

Abstract The structure of biomaterial is interest in biomimetic and biomechanics research. The physical properties, mechanical, characteristic of twisting and bending of plant tendrils are also thought-provoking to study. In this study, we proposed an innovative biomaterial spring device for holding an object and providing support. The device uses Coccinia grandis (L.) Voigt tendril as inspired by the relations of left-hand (LH) and right-hand (RH) climbing tendrils with a single branch. To study the morphology and anatomy, testing stress, length, number of the helix of the tendril which relation of mimic string material Coccinia grandis (L.) Voigt tendril and helical metal which have two helixes, three helixes and four helixes were tested by using food texture analysis. The anatomical showed many cell types and slight differences between straight and coiled tendrils. The result showed the tendril of two helixes has the highest stress and four helixes the least. Also, tensile testing showed that the number of helixes does not affect the stress of the tendril models.</jats:p