1,508 research outputs found

    Linear Response Calculations of Lattice Dynamics in Strongly Correlated Systems

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    We introduce a new linear response method to study the lattice dynamics of materials with strong correlations. It is based on a combination of dynamical mean field theory of strongly correlated electrons and the local density functional theory of electronic structure of solids. We apply the method to study the phonon dispersions of a prototype Mott insulator NiO. Our results show overall much better agreement with experiment than the corresponding local density predictions.Comment: 4 pages, 2 figure

    Korelasi antara Aspek Motivasi dalam Penyusunan Anggaran dengan Efektivitas Pelaksanaan Program Kegiatan pada Pemerintahan Provinsi Nanggroe Aceh Darussalam

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    This objective of research is aimed at finding out the correlations of motivation aspects in budget arrangement and effectiveness of program imple-mentation of the Provincial Government of Nanggroe Aceh Darussalam. Motivation aspects consist of working achievement, degree of complications on budgeting, degree of fairness on budgeting, and style of leadership.The samples comprice 100 employees selected by using simple random sampling. The data were collected by questionnaires, which have been tested both for its validity and for reliability. The Product Moment Correlation is used to test the validity of the data with the degree of significance 0.05 while the reliability is tested by using Alpha Cronbach technique.The result of this research shows that: (1) t test by partial degree of complication variable and degree of fairness variable has a significant correlation on effectiveness of program implementation. Style of leadership variable by partial also has significant correlation on effectiveness of program implementation, but working achievement variable has no significant correlation on effectiveness of program implementation. (2) there is positive correlation between four independent variables and dependent variable. (3) coefficient correlation shows that correlation between dependent variables and independent variable is 0.465. (4) R square is 0.12, indicates that there is 88% other aspects influence effectiveness of program implementation of the provincial government of Nanggroe Aceh Darussalam

    Local Self-Energy Approach For Electronic Structure Calculations

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    Using a novel self-consistent implementation of Hedin's GW perturbation theory we calculate space and energy dependent self-energy for a number of materials. We find it to be local in real space and rapidly convergent on second-- to third-- nearest neighbors. Corrections beyond GW are evaluated and shown to be completely localized within a single unit cell. This can be viewed as a fully self consistent implementation of the dynamical mean field theory for electronic structure calculations of real solids using a perturbative impurity solver.Comment: 5 pages, 2 figure

    Inovasi Gadjah Mada Bamboo Shelter (GAMBOOSTER) sebagai Smart And Eco Friendly Temporary Shelter Bagi Korban Bencana

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    Various regions in Indonesia are often had a natural disaster. Ironically handling of post-disaster still seem indolent and not ready especially fullfill requirement of shelters. Orientation of the above problem, we have an innovations arise to make shelters with various of design concept, include : shelters that can harvest the rain water, earthquake resistant, eco friendly materials, get implementing smart technology system as a puzzle and implement the dynamic wall system. The main materials used in our innovation is bamboo with the economic, low cost and sustainable when it compared to wood or aother materials. Same with implementing of other building work, temporary shelter that we construct need standart tools equipment builders. This activity is divided in two types of work, there\u27s fabrication site and construction site. On the implementation phase, we can starting from a literature search and discussion, survey tools and materials, permitting laboratories and make a shop drawing. After that, we can make the temporary shelters from the procurement of equipment and materials, work columns, beams, sloof, the walls and floor plate work, trust and roof work, finishing, construction phase and packaging. This product innovation is also equipped with a guide book for constructed, so our expectation is the temporary shelter can construct with effective and effisienly

    Self-consistent Green function approach for calculations of electronic structure in transition metals

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    We present an approach for self-consistent calculations of the many-body Green function in transition metals. The distinguishing feature of our approach is the use of the one-site approximation and the self-consistent quasiparticle wave function basis set, obtained from the solution of the Schrodinger equation with a nonlocal potential. We analyze several sets of skeleton diagrams as generating functionals for the Green function self-energy, including GW and fluctuating exchange sets. Their relative contribution to the electronic structure in 3d-metals was identified. Calculations for Fe and Ni revealed stronger energy dependence of the effective interaction and self-energy of the d-electrons near the Fermi level compared to s and p electron states. Reasonable agreement with experimental results is obtained

    Pengaruh Stock Split terhadap Harga dan Likuiditas Saham

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    This study aimed to analyze the effect of stock split announcement to the stock priceand liquidity in the Indonesian Stock Exchange by taking a sample of 34 firms in theperiod 2002 to 2005. During the study period 111 days, divided into two periods,100 day estimation period and event period 11 days including five days before, oneday events, and five days after. To examine the changes in prices made during thetest period abnormal return events with analysis based on the concept of marketmodel. Observed stock liquidity through trading activities/Tranding Volume Activity(TVA). The testing device used is one sample t-test and paired sample t-test. Theresults show that there is a significant abnormal return on stock split, there aresignificant differences in abnormal return between the periods before and after thestock split, and there was no significant difference in the activity of stock tradingvolume between the period before and after the stock spl

    Calcineurin/NFAT Activation-Dependence of Leptin Synthesis and Vascular Growth in Response to Mechanical Stretch

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    Background and Aims- Hypertension and obesity are important risk factors of cardiovascular disease. They are both associated with high leptin levels and have been shown to promote vascular hypertrophy, through the RhoA/ROCK and ERK1/2 phosphorylation. Calcineurin/NFAT activation also induces vascular hypertrophy by upregulating various genes. This study aimed to decipher whether a crosstalk exists between the RhoA/ROCK pathway, Ca+2/calcineurin/NFAT pathway, and ERK1/2 phosphorylation in the process of mechanical stretch-induced vascular smooth muscle cell (VSMC) hypertrophy and leptin synthesis. Methods and Results- Rat portal vein (RPV) organ culture was used to investigate the effect of mechanical stretch and exogenous leptin (3.1 nM) on VSMC hypertrophy and leptin synthesis. Results showed that stretching the RPV significantly upregulated leptin secretion, mRNA and protein expression, which were inhibited by the calcium channel blocker nifedipine (10 μM), the selective calcineurin inhibitor FK506 (1 nM) and the ERK1/2 inhibitor PD98059 (1 μM). The transcription inhibitor actinomycin D (0.1M) and the translation inhibitor cycloheximide (1 mM) significantly decreased stretch-induced leptin protein expression. Mechanical stretch or leptin caused an increase in wet weight changes and protein synthesis, considered as hypertrophic markers, while they were inhibited by FK506 (0.1 nM; 1 nM). In addition, stretch or exogenous leptin significantly increased calcineurin activity and MCIP1 expression whereas leptin induced NFAT nuclear translocation in VSMCs. Moreover, in response to stretch or exogenous leptin, the Rho inhibitor C3 exoenzyme (30 ng/mL), the ROCK inhibitor Y-27632 (10 μM), and the actin depolymerization agents Latrunculin B (50 nM) and cytochalasin D (1 μM) reduced calcineurin activation and NFAT nuclear translocation. ERK1/2 phosphorylation was inhibited by FK506 and C3. Conclusions- Mechanical stretch-induced VSMC hypertrophy and leptin synthesis and secretion is mediated by Ca2+/calcineurin/NFAT activation. RhoA/ROCK and ERK1/2 activation are critical for mechanical stretch-induced calcineurin activation

    Adverse drug events associated with vitamin K antagonists: factors of therapeutic imbalance

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    Nancy El-Helou, Amal Al-Hajje, Rola Ajrouche, Sanaa Awada, Samar Rachidi, Salam Zein, Pascale SalamehClinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Beirut, LebanonBackground: Adverse drug events (ADE) occur frequently during treatment with vitamin K antagonists (AVK) and contribute to increase hemorrhagic risks.Methods: A retrospective study was conducted over a period of 2 years. Patients treated with AVK and admitted to the emergency room of a tertiary care hospital in Beirut were included. The aim of the study was to identify ADE characterized by a high international normalized ratio (INR) and to determine the predictive factors responsible for these events. Statistical analysis was performed with the SPSS statistical package.Results: We included 148 patients. Sixty-seven patients (47.3%) with an INR above the therapeutic range were identified as cases. The control group consisted of 81 patients (54.7%) with an INR within the therapeutic range. Hemorrhagic complications were observed in 53.7% of cases versus 6.2% of controls (P < 0.0001). No significant difference was noticed between cases and controls regarding the indication and the dose of AVK. Patients aged over 75 years were more likely to present an INR above the therapeutic range (58.2%, P = 0.049). Recent infection was present in 40.3% of cases versus 6.2% of controls (P < 0.0001) and hypoalbuminemia in 37.3% of cases versus 6.1% of controls (P < 0.0001). Treatment with antibiotics, amiodarone, and anti-inflammatory drugs were also factors of imbalance (P < 0.0001).Conclusion: Many factors may be associated with ADE related to AVK. Monitoring of INR and its stabilization in the therapeutic range are important for preventing these events.Keywords: adverse drug events, vitamin K antagonists, bleeding risks, therapeutic imbalanc
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