Buffered-microgrid Structure for Future Power Networks; a Seamless Microgrid Control

This paper proposes a new structure and control scheme for future microgrid-based power system, which is designed to achieve a seamless operation in both islanded and grid-connected modes, while the load is appropriately shared by all units (i.e. renewable sources, energy storage systems and the grid). The proposed method, which involves physical separation of the microgrid from the grid by using AC/DC/AC converters, ensures safe, secure and seamless operation of both modes. Such a “buffered” structure enables reduction in the transmission losses by reducing the exchanged energy with the grid through using a dead-zone in the control of the buffering AC/DC/AC converter. An inverse-droop control technique has been implemented to control the voltage magnitude and frequency, using current control in the dq-frame. PSCAD/EMTDC software has been used to validate the proposed method through simulating different scenarios. The solution provides a simple, smooth, and communication-free decentralized control for multi-sources microgrids. Moreover, the proposed buffered structure separates the dynamics of the microgrid and the grid, which enables a faster microgrid voltage and frequency control and protects the grid and the microgrid from faults on the other side

Environmental stimuli shape microglial plasticity in glioma

In glioma, microglia and infiltrating macrophages are exposed to factors that force them to produce cytokines and chemokines, contributing to tumor growth and maintaining a pro-tumorigenic, immunosuppressed microenvironment. We demonstrate that housing glioma-bearing mice in enriched environment (EE) reverts the immunosuppressive phenotype of infiltrating myeloid cells, by modulating inflammatory gene expression. Under these conditions, branching and patrolling activity of myeloid cells is increased, and their phagocytic activity is promoted. Modulation of gene expression depends on interferon-(IFN) g produced by natural killer (NK) cells, disappearing in mice depleted of NK cells or lacking IFN-g, and was mimicked by exogenous interleukin-15 (IL-15). Further, we describe a key role for BDNF produced in the brain of mice housed in EE in mediating the expression of IL-15 in CD11b+ cells. These data define novel mechanisms linking environmental cues to the acquisition of a pro-inflammatory, anti-tumor microenvironment in mouse brain

Impact of Enriched Environment on Murine T Cell Differentiation and Gene Expression Profile

This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permissionThis study was not supported by any grant funding. GP and SB are supported by QMUL Principal and MRC PhD studentships, respectively

The biology and genetics of curly hair

YesHair fibres show wide diversity across and within all human populations, suggesting that hair fibre form and colour have been subject to much adaptive pressure over thousands of years. All human hair fibres typically have the same basic structure. However, the three-dimensional shape of the entire fibre varies considerably depending on ethnicity and geography, with examples from very straight hair with no rotational turn about the long axis, to the tightly sprung coils of African races. The creation of the highly complex biomaterials in hair follicle and how these confer mechanical functions on the fibre so formed is a topic that remains relatively unexplained thus far. We review the current understanding on how hair fibres are formed into a nonlinear coiled form and which genetic and biological factors are thought to be responsible for hair shape. We report on a new GWAS comparing low and high curl individuals in South Africa, revealing strong links to polymorphic variation in trichohyalin, a copper transporter protein CUTC and the inner root sheath component keratin 74. This builds onto the growing knowledge base describing the control of curly hair formation.Unilever R&