Performance investigation of ANFIS and PSO DFFP based boost converter with NICI using solar panel

The modeling and development of the boost DC to DC converter with Partial Swarm Optimization with Distinctive Feed Forward Propagation (PSO-DFFP) controller for hybrid power systems including solar panels. The static and dynamic investigation of the developed PSO DEEP controller is presented. The PSO-DFFP controller has been designed to improve the operating efficiency and reduces the input converter current ripple. The PSO DFFP controller is developed and performance is compared with ANFIS and FLC. The developed system reduces the switching losses and voltage drops in switching modes. The designed system is demonstrated and developed with 200W, 100kHz model. The investigation results is exposed that the developed PSO DEEP system is an acceptable for SOLAR applications

Atypical presentation of Hand foot mouth disease (HFMD) caused by enterovirus serotype Coxsackievirus A6, in India

A 27-year-old male presented in the OPD of Naval Hospital in Port Blair, Andaman Islands, India, in 2011 with a history of low-grade fever associated with malaise and a pruritic skin rash. Case 2 – A 17-year-old male student reported to the OPD at Naval Hospital, Kochi Kerala, India, in August 2015. He presented with eruptions on both the palm and soles with a history of high-grade fever for the past 3–4 days. Clinically, both the cases were diagnosed as hand, foot, and mouth disease (HFMD). Both samples were tested against measles virus and varicella-zoster IgM antibodies by enzyme immunoassay and found negative. Stool sample (case 1) and lesion swab (case 2) were processed by enterovirus reverse transcription polymerase chain reaction and phylogenetic analysis, and both were positive for enterovirus human coxsackievirus A6 (CVA6) (untranslated region [UTR]). Phylogenetic analysis also confirmed that both the CVA6 etiology belonged to the genotype F. HFMD in adults often asymptomatic and very few patients get atypical symptoms. Clinical diagnosis is often troublesome to identify HFMD in such cases. An epidemiological surveillance/vigilance is essential to document these atypical cases in near future in developing countries like India

Detection of ovine leptospirosis in various agro-climatic zones of Odisha in the aftermath of cyclone Hudhud using a multi-faceted approach

Leptospirosis is an important emerging zoonotic disease responsible for hampering the productivity of ovine husbandry worldwide. A total of 1,877 ovine serum samples were collected from five agro-climatic zones of Odisha following the aftermath of cyclone Hudhud. A multifaceted approach for detection of anti-Leptospira antibodies using Microscopic Agglutination Test (MAT), in-house developed rapid spot tests such as recombinant Loa22 antigen-based Latex Agglutination Test (rLoa22 LAT) and rLoa22-based IgG Dot ELISA Dipstick Test (rLoa22 IgG DEDT) were developed. Further, nucleic acid detection of leptospirosis employing Polymerase Chain Reaction (PCR) utilizing LigBF/LigBR and G1/G2 were performed. Additionally, renal histopathology of kidneys from MAT positive sheep was also used for investigating leptospirosis in sheep. MAT results for ovine sera revealed a seropositivity of 16.62% (312/1877) with maximum agglutinins detected against serovar Pomona. Among agro- climatic zones, South Eastern Ghat recorded the highest seroprevalence while Western Central Table Land recorded the lowest seroprevalence for ovine leptospirosis. A total of 296 and 345 sera tested positive by rLoa22 LAT and rLoa22 IgG DEDT respectively. PCR performed on kidneys of MAT positive sheep revealed amplicons for LigBF/ LigBR and G1/G2 primers in 104 and 93 sheep respectively. The histopathological evidence such as tubular atrophy, severe tubular degeneration and necrosis with interstitial and periglomerular fibrosis suggestive of chronic leptospirosis was present in 78 sheep. This multi-pronged approach of employing a battery of diagnostic tests would allow the execution of mediation strategies to curb ovine leptospirosis following natural calamities such as cyclones

A DNA Vaccine against Chikungunya Virus Is Protective in Mice and Induces Neutralizing Antibodies in Mice and Nonhuman Primates

Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus indigenous to tropical Africa and Asia. Acute illness is characterized by fever, arthralgias, conjunctivitis, rash, and sometimes arthritis. Relatively little is known about the antigenic targets for immunity, and no licensed vaccines or therapeutics are currently available for the pathogen. While the Aedes aegypti mosquito is its primary vector, recent evidence suggests that other carriers can transmit CHIKV thus raising concerns about its spread outside of natural endemic areas to new countries including the U.S. and Europe. Considering the potential for pandemic spread, understanding the development of immunity is paramount to the development of effective counter measures against CHIKV. In this study, we isolated a new CHIKV virus from an acutely infected human patient and developed a defined viral challenge stock in mice that allowed us to study viral pathogenesis and develop a viral neutralization assay. We then constructed a synthetic DNA vaccine delivered by in vivo electroporation (EP) that expresses a component of the CHIKV envelope glycoprotein and used this model to evaluate its efficacy. Vaccination induced robust antigen-specific cellular and humoral immune responses, which individually were capable of providing protection against CHIKV challenge in mice. Furthermore, vaccine studies in rhesus macaques demonstrated induction of nAb responses, which mimicked those induced in convalescent human patient sera. These data suggest a protective role for nAb against CHIKV disease and support further study of envelope-based CHIKV DNA vaccines

Performance Analysis of PSO DFFP Based DC-DC Converter with Non Isolated CI using PV Panel

This article presents the modeling and development of a DC-DC converter with Partial Swarm Optimization with Distinctive Feed Forward Propagation (PSO-DFFP) controller for hybrid power systems, including photovoltaic panels. The transient and dynamic analysis of the proposed controller has been presented. The PSO-DFFP controller has been designed to improve the operating efficiency and reduces the input converter current ripple. The ANFIS and PSO DFFP controllers are developed, and the performance of the system is compared. The proposed system reduces the switching losses and voltage drops in switching modes. The proposed system is demonstrated and developed with a 200W, 100kHz model. From the experimental results, it can be exposed that the proposed system is acceptable for PV applications

Performance Analysis of Hybrid Multi-Port AC-DC/DC-DC Embedded Based Energy Flow Optimizing Using Resilient Power Flow Control (RPFC) Technique

In recent decades, the utilization of renewable power sources has proven to be a reliable and clean vitality more universal, and with specific ultimate goals to achieve efficient and renewable energy power generation. The proposed system is improve the stabilize energy flow between micro grids and the main grid. The power generation of the each and every renewable sources are monitored and controlled by the proposed Resilient Power Flow Control (RPFC) system and also the energy flow variation of the grid system is analyzed and presented in this paper. This work demonstrates the role of energy routers in optimizing the efficient and flexible way of energy stabilization in grid system. This analysis model establishes the entire system, including power routers, interconnected microcircuits, and the main grid. Interconnected microcircuits were analyzed by various controller facilitated by power routers, and corresponding control strategies were developed. The proposed system shows the effectiveness and reliability of the control strategy for micro-grid interconnection and flexible energy flow correspondence.</jats:p