Envisioning work : an autism friendly and anxiety free office

Autism spectrum disorder (ASD) refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication. It is estimated that worldwide 1 in 160 children has ASD, and in China, about 1 in 69 children has ASD. There are many successful educational environments specially designed for people on the spectrum to support learning, understanding, and behaving. However, after graduating, it is usually very hard for people on the spectrum to move toward independence because there is a huge difference between school environments and office environments. Most office environments are designed to meet the majority workers’ needs, but they are not supportive for people on the spectrum. There are very few innovative companies that recognize the unique skills that people on the spectrum and design their office carefully to support them. Most companies don’t consider the special needs of people on the spectrum while designing their office, which makes people with ASD struggle to find jobs because of the anxiety that might be caused by unsupportive workspaces. An office’s interior configurations has a great impact on employees’ performance. It is important to create a supportive office environment for both people on the spectrum and those who have other forms of anxiety at work. The key to an autism friendly and anxiety free office is balance. The space will be divided in a way to create a balance between working and relaxing, private and open, as well as light and shade. Focusing on productivity, privacy, and flexibility, I will create a system that can be applied to any type of building to make an office ASD friendly. The system provides employees the personal space they need, ABSTRACT and at the same time it encourages employees to communicate. The proposed site is located in Laodaowai District, Harbin, China, and the existing site conditions are not ideal for people on the spectrum for their work performance. The site will be an example of how the autism friendly system can be applied to any type of building, even one in a problematic setting. Most people on the spectrum have sensory problems. According to Autism Speaks, In 2013, the American Psychiatric Association added sensory sensitivities to the symptoms that help diagnose autism. Autism’s sensory issues can involve both hyper-sensitivities (over-responsiveness) and hypo-sensitivities (under-responsiveness) to a wide range of stimuli. It is important to balance the environment through the five senses to make sure that they are not experiencing sensory overload or sensory deprivation. The ideal autism friendly environment should take care of the special needs of people on the spectrum. People on the spectrum need a lot of personal space, and it is important to make sure that they have enough room to be alone. In addition, people on the spectrum do not like unpredictable moments, sharp corners, long corridors, and irregular shapes that make them feel insecure and puzzled. Complicated circulation should also be avoided because they are easy to get lost. Way-finding is a very important element in an autism friendly office. It is important to use colors, patterns, textures, signs..., to navigate people through the office. Not only people on the spectrum are invited to the office. General population, people who have anxiety problems and people who desire a relaxing working environment are all welcomed to work in the office. The employees will get the comfort of working from home, as well as the productivity of working at a formal office

Processing of Individual Items during Ensemble Coding of Facial Expressions

There is growing evidence that human observers are able to extract the mean emotion or other type of information from a set of faces. The most intriguing aspect of this phenomenon is that observers often fail to identify or form a representation for individual faces in a face set. However, most of these results were based on judgments under limited processing resource. We examined a wider range of exposure time and observed how the relationship between the extraction of a mean and representation of individual facial expressions would change. The results showed that with an exposure time of 50 ms for the faces, observers were more sensitive to mean representation over individual representation, replicating the typical findings in the literature. With longer exposure time, however, observers were able to extract both individual and mean representation more accurately. Furthermore, diffusion model analysis revealed that the mean representation is also more prone to suffer from the noise accumulated in redundant processing time and leads to a more conservative decision bias, whereas individual representations seem more resistant to this noise. Results suggest that the encoding of emotional information from multiple faces may take two forms: single face processing and crowd face processi

GRIK3 rs490647 is a Common Genetic Variant between Personality and Subjective Well-being in Chinese Han Population

Personality and subjective well-being (SWB) have been suggested to be strongly related in previous studies. This study was intended to confirm the relationship between personality and SWB and tried to seek out the genetic variants which underlie both personality and SWB. The subjects were 890 participants from Chinese Han population. We evaluated their personality using the Big Five Inventory (BFI) and used the Satisfaction With Life Scale (SWLS) to reflect their SWB. Five single nucleotide polymorphisms (SNPs) were selected from the literature (rs1426371, rs2164273, rs322931, rs3756290, rs490647) and genotyped for genetic association study. We found negative correlations between neuroticism and SWB. On the contrary, extraversion and agreeableness were positively associated with SWB. Three SNPs (rs2164273, rs3756290, rs490647) out of the five were found to connect with personality (extraversion, neuroticism, conscientiousness and openness to experience) and rs490647 variants of GRIK3 was also associated with SWB. Individuals carrying G allele at this site were predisposed to have lower risk to be neuroticism and greater chance to be extraverted, open and satisfied with their life. In summary, our study revealed that rs490647 might be a good candidate genetic variant for personality and SWB in Chinese Han population

Roadmap on printable electronic materials for next-generation sensors

The dissemination of sensors is key to realizing a sustainable, ‘intelligent’ world, where everyday objects and environments are equipped with sensing capabilities to advance the sustainability and quality of our lives—e.g., via smart homes, smart cities, smart healthcare, smart logistics, Industry 4.0, and precision agriculture. The realization of the full potential of these applications critically depends on the availability of easy-to-make, low-cost sensor technologies. Sensors based on printable electronic materials offer the ideal platform: they can be fabricated through simple methods (e.g., printing and coating) and are compatible with high-throughput roll-to-roll processing. Moreover, printable electronic materials often allow the fabrication of sensors on flexible/stretchable/biodegradable substrates, thereby enabling the deployment of sensors in unconventional settings. Fulfilling the promise of printable electronic materials for sensing will require materials and device innovations to enhance their ability to transduce external stimuli—light, ionizing radiation, pressure, strain, force, temperature, gas, vapours, humidity, and other chemical and biological analytes. This Roadmap brings together the viewpoints of experts in various printable sensing materials—and devices thereof—to provide insights into the status and outlook of the field. Alongside recent materials and device innovations, the roadmap discusses the key outstanding challenges pertaining to each printable sensing technology. Finally, the Roadmap points to promising directions to overcome these challenges and thus enable ubiquitous sensing for a sustainable, ‘intelligent’ world

Efficiency Evaluation of Wastewater Pollution and Water Disease Efficiency in China Based on the Dynamic Two-Stage DEA Method

China is not only short of fresh water resources per capita, but also faces a serious problem of water pollution in recent years, with 190 million people suffering from excessive levels of harmful substances in their drinking water. Such as arsenic poisoning and fluorosis and other endemic water diseases high incidence. As a series of water pollution prevention plan of action by the Chinese government announced that, this paper uses the modified Undesirable Dynamic Network model empirical analysis of China's 31 provincial administrative region economic growth, wastewater treatment, and water disease control efficiency between 2013 and 2017. The results show that the efficiency of water pollution disease in all four regions of China and the total efficiency in the three regions of east, west and central China all show a decreasing trend, and the efficiency scores and rankings of all provinces and cities within the region fluctuate greatly. The eastern region with the most developed economy has the best overall performance, with higher efficiency in Water consumption and Water disease control. However, the efficiency of wastewater treatment in northeast China is stable and better. Given the high level of economic development in China and the results of the above mentioned efficiency in water pollution and water diseases, improving the efficiency and quality of wastewater treatment in China is regarded as an important factor in achieving the strategic goal of green growth.</jats:p

Predictable Fluctuations in Excitatory Synaptic Strength Due to Natural Variation in Presynaptic Firing Rate.

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A modified dynamic DEA model to assess the wastewater treatment efficiency: perspective from Yangtze River and Non-Yangtze River Basin

AbstractThe wastewater treatment efficiency is crucial to constructing a livable ecological environment and promoting the sustainable development of economy and society. The differences in natural conditions, economic development and local policies between the Yangtze River Basin (YRB) and the Non-Yangtze River Basin (NYRB) increase the difficulty of wastewater treatment in governance. This study uses a modified Dynamic Data Envelopment Analysis (DEA) model to assess the wastewater treatment from 2013 to 2020, and divides the study period into two stages: the first stage (2013–2017) assesses the wastewater treatment efficiency of 18 provinces and cities in YRB and 12 provinces and cities in NYRB; the second stage (2018–2020) conducts statistical analysis of wastewater discharge pollutants in YRB and NYRB. The results conclude that the total wastewater treatment efficiency is generally low, but polarization is quite prominent. Among total wastewater treatment efficiency, NYRB scored 0.504, or slightly higher than YRB (0.398). In terms of expense efficiency, both NYRB and YRB scored below 0.4. In terms of chemical oxygen demand (COD) output efficiency, YRB (0.488) is better than NYRB (0.420). The second stage of statistical analysis presents that pollutant emissions are still high; the regions need to increase wastewater treatment investment and improve wastewater treatment efficiency.</jats:p

Predictable fluctuations in excitatory synaptic strength due to natural variation in presynaptic firing rate

AbstractMany controlled, in vitro studies have demonstrated how postsynaptic responses to presynaptic spikes are not constant but depend on short-term synaptic plasticity (STP) and the detailed timing of presynaptic spikes. However, the effects of short-term plasticity (depression and facilitation) are not limited to short, sub-second timescales. The effects of STP appear on long timescales as changes in presynaptic firing rates lead to changes in steady-state synaptic transmission. Here we examine the relationship between natural variations in the presynaptic firing rates and spike transmission in vivo. Using large-scale spike recordings in awake mice from the Allen Institute Neuropixels dataset, we first detect putative excitatory synaptic connections based on cross-correlations between the spike trains of millions of pairs of neurons. For the subset of pairs where a transient, excitatory effect was detected, we use a model-based approach to track fluctuations in synaptic efficacy and find that efficacy varies substantially on slow (∼1 minute) timescales over the course of these recordings. For many connections, the efficacy fluctuations are correlated with fluctuations in the presynaptic firing rate. To understand the potential mechanisms underlying this relationship, we then model the detailed probability of postsynaptic spiking on a millisecond timescale, including both slow changes in postsynaptic excitability and monosynaptic inputs with short-term plasticity. The detailed model reproduces the slow efficacy fluctuations observed with many putative excitatory connections, suggesting that these fluctuations can be both directly predicted based on the time-varying presynaptic firing rate and, at least partly, explained by the cumulative effects of STP.</jats:p