1,053 research outputs found

    Critical Heat Flux under Flow Oscillation in a Natural Circulation Loop of Liquid Nitrogen

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    In a natural circulation loop,flow instability,such as density wave oscillation, occurs under a certain operating condition,while the influence of flow oscillation on the heat transfer is not well understood so far. Experiment was conducted by using a natural circulation loop of liquid nitrogen with test tubes of dimensions of 3.0mm/5.0mm I.D.,and 900mm heated length. It was indicated that the heat transfer correlation of Schrock-Grossman was in good agreement with experimental results in the saturated boiling region even under oscillatory flow condition,and that the correlation of Roko was in good agreement with the experimental results of post-dryout heat transfer even under oscillatory flow condition. On the other hand,the CHF was well predicted using the lumped-parameter model,taking account of the circulation rate, oscillation frequency and amplitude of mass flux in the natural circulation loop

    Combined treatment with dipeptidyl peptidase 4 (DPP4) inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosal glucagon-like peptide-2 concentration.

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    The gut incretin glucagon-like peptide-1 (GLP-1) and the intestinotropic hormone GLP-2 are released from enteroendocrine L cells in response to ingested nutrients. Treatment with an exogenous GLP-2 analogue increases intestinal villous mass and prevents intestinal injury. Since GLP-2 is rapidly degraded by dipeptidyl peptidase 4 (DPP4), DPP4 inhibition may be an effective treatment for intestinal ulcers. We measured mRNA expression and DPP enzymatic activity in intestinal segments. Mucosal DPP activity and GLP concentrations were measured after administration of the DPP4 inhibitor sitagliptin (STG). Small intestinal ulcers were induced by indomethacin (IM) injection. STG was given before IM treatment, or orally administered after IM treatment with or without an elemental diet (ED). DPP4 mRNA expression and enzymatic activity were high in the jejunum and ileum. STG dose-dependently suppressed ileal mucosal enzyme activity. Treatment with STG prior to IM reduced small intestinal ulcer scores. Combined treatment with STG and ED accelerated intestinal ulcer healing, accompanied by increased mucosal GLP-2 concentrations. The reduction of ulcers by ED and STG was reversed by co-administration of the GLP-2 receptor antagonist. DPP4 inhibition combined with luminal nutrients, which up-regulate mucosal concentrations of GLP-2, may be an effective therapy for the treatment of small intestinal ulcers

    Current Performance and On-Going Improvements of the 8.2 m Subaru Telescope

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    An overview of the current status of the 8.2 m Subaru Telescope constructed and operated at Mauna Kea, Hawaii, by the National Astronomical Observatory of Japan is presented. The basic design concept and the verified performance of the telescope system are described. Also given are the status of the instrument package offered to the astronomical community, the status of operation, and some of the future plans. The status of the telescope reported in a number of SPIE papers as of the summer of 2002 are incorporated with some updates included as of 2004 February. However, readers are encouraged to check the most updated status of the telescope through the home page, http://subarutelescope.org/index.html, and/or the direct contact with the observatory staff.Comment: 18 pages (17 pages in published version), 29 figures (GIF format), This is the version before the galley proo

    Enhanced light emission from improved homogeneity in biaxially suspended Germanium membranes from curvature optimization

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    A silicon compatible light source is crucial to develop a fully monolithic silicon photonics platform. Strain engineering in suspended Germanium membranes has offered a potential route for such a light source. However, biaxial structures have suffered from poor optical properties due to unfavorable strain distributions. Using a novel geometric approach and finite element modelling (FEM) structures with improved strain homogeneity were designed and fabricated. Micro-Raman (μ-Raman) spectroscopy was used to determine central strain values. Micro-photoluminescence (μ-PL) was used to study the effects of the strain profiles on light emission; we report a PL enhancement of up to 3x by optimizing curvature at a strain value of 0.5% biaxial strain. This geometric approach offers opportunity for enhancing the light emission in Germanium towards developing a practical on chip light source

    Designing rotational motion of charges on plasmonic nanostructures excited by circularly polarized light

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    Rotational motion of charges in plasmonic nanostructures plays an important role in transferring angular momentum between light and matter on the nanometer scale. Although sophisticated control of rotational charge motion has been achieved using spatially structured light, its extension to simultaneous excitation of the same charge motion in multiple nanostructures is not straightforward. In this study, we perform model calculations to show that spatially homogeneous circularly polarized (CP) light can excite rotational charge motions with a high degrees of freedom by exploiting the rotational symmetry of the plasmonic structure and that of the plasmon mode. Finite-difference time-domain simulations demonstrate selective excitation of rotational charge motion for both isolated nanoplates and periodic array structures, showing that complex charge rotations can be manipulated by plane CP waves in a wide range of plasmonic structures.Comment: 9 pages, 5 figure
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