214 research outputs found

    Prevalence of feline herpesvirus 1, feline calicivirus and Chlamydophila felis in clinically normal cats at a Korean animal shelter

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    The prevalence of feline herpesvirus-1 (FHV-1), feline calicivirus (FCV), and Chlamydophila (C.) felis was studied in cats of an animal shelter in Korea. Total 78 cats without ocular and upper respiratory tract disease were examined. Specimens were obtained from ocular conjunctiva and oropharynx. Using multiplex polymerase chain reaction (PCR) and reverse transcription PCR, three pathogens were simultaneously detected. In examined 78 cats, 49 (63%) cats were positive for FHV-1. However, all specimens were negative for C. felis and FCV. In conclusion, many cats recovered from FHV-1 infection remain subclinical carriers in shelter environment

    Anel de tensão capsular isolado e associado à lente intraocular acrílica dobrável na opacidade de cápsula posterior após facoemulsificação em cães

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    The purpose of the study was to determine whether capsular tension ring (CTR) alone or associated with the implantation of an intraocular lens (IOL) could decrease the occurrence of posterior capsular opacification (PCO) after phacoemulsification cataract surgery in dogs. Twenty eyes of client-owned dogs with immature or mature cataracts were included in this study. In all the animals, any ophthalmic or systemic concurrent disease was excluded. The eyes were randomly selected to receive CTR alone or in association with the IOL. Laser flaremetry and clinical evaluations were conducted on post-operative days 2, 7, 14, 21 and 28. Fundus photographs were taken at the 28th and then every 30 days, up to 180 days. The results showed more inflammatory response on eyes with IOLs, although among the parameters evaluated, solely the synechiae showed significant statistical differences. Nevertheless, in both techniques almost no PCOs occurred at the end of the evaluations. These results suggest that the CTRs can be useful in the prevention of the post-operative capsular opacities, with minor complicationsO objetivo do estudo foi determinar se o anel de tensão capsular (ATC), isoladamente ou associado à implantação de uma lente intraocular, poderia diminuir a ocorrência de opacificação da cápsula posterior (OCP) após a cirurgia de catarata por facoemulsificação em cães. Para tanto, cães portadores de catarata imatura ou madura foram avaliados, perfazendo um total de vinte olhos. Em todos os animais, foram excluídas quaisquer doenças oftálmicas e sistêmicas concomitantes. Os olhos foram selecionados aleatoriamente para receber o anel (ATC) isolado ou em associação com a lente. Flaremetria a laser e avaliações clínicas foram realizadas aos 2, 7, 14, 21, e 28 dias de pós-operatório. Fotografias foram tomadas aos 28 e a seguir a cada 30 dias, até os 180 dias. Os resultados mostraram inflamação mais importante nos olhos com IOL, embora, entre os parâmetros avaliados, apenas nas sinéquias houve diferença estatisticamente significativa. No entanto, em ambas as técnicas, quase nenhuma OCP ocorreu até o momento final das avaliações. Tais resultados sugerem que os anéis de tensão capsular (ATC) podem ser úteis na prevenção da opacidade capsular pós-operatória, sem complicações decorrentesFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPQ)Universidade Estadual Paulista (UNESP) - Faculdade de Ciências Agrárias e Veterinárias de Jaboticabal (FCVAJ),14884-900, Jaboticabal, SP, Brasil.Universidade Estadual Paulista (UNESP) - Faculdade de Medicina Veterinária de Araçatuba (FMVA), UNESP, Araçatuba, SP, Brasil.Universidade Estadual Paulista (UNESP) - Faculdade de Ciências Agrárias e Veterinárias de Jaboticabal (FCVAJ),14884-900, Jaboticabal, SP, Brasil.Universidade Estadual Paulista (UNESP) - Faculdade de Medicina Veterinária de Araçatuba (FMVA), UNESP, Araçatuba, SP, Brasil.FAPESP: 2009/51773-4CNPq: 300833/2010-

    Epidemiological status of felid herpesvirus type-1 and feline calicivirus infections in Brazil

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    Feline calicivirus (FCV) and felid herpesvirus type-1 (FeHV-1) are the main infectious agents of domestic and wild felines worldwide. The FCV and FeHV-1 viruses were isolated in Brazil in 1988 and 2012, respectively. Serology surveys were performed among domestic feline in the State of Rio Grande do Sul and among wild felines in central Brazilian States. Felines with acute or chronic infections may become carriers for both viruses and, viral transmission occurs mainly by ocular and nasal secretions. In addition, FCV may be transmitted by oropharyngeal secretion and fomites. The clinical signs commonly observed in cats are fever, sneezing, coughing and nasal and ocular discharge; however, oral lesions are restricted to FCV infection. A systemic syndrome showing hemorrhagic lesions, alopecia, facial edema and jaundice has been associated with FCV. Attenuated as well as inactivated vaccines against FCV and FeHV-1 were developed in the middle 1970s, and they are effective at reducing the presentation/development of the diseases, but they are not capable of eliminating the persistence of FCV and FeHV-1. This article presents a brief review of the main aspects of the FCV and FeHV-1 infections, with an emphasis in the current situation on the domestic feline population from Brazil

    Superficial keratectomy and 360º conjunctival flap for bullous keratopathy in a dog: a case report

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    A case of a two-year-old male Pinscher with a history of discomfort in the right eye was reported. The left eye had been enucleated by the referring veterinarian due to the same symptom with unsuccessful clinical treatment. The Schirmer tear test value was elevated and a decreased intraocular pressure was observed by applanation tonometry. Biomicroscopy revealed profuse corneal edema and keratoconus and fluorescein staining was negative. Gonioscopy and ophthalmoscopy did not provide any relevant data due to the corneal alterations. Bullous keratopathy was diagnosed. Surgery was performed in two steps: 1) superficial keratectomy and 360º conjunctival flap, and 2) superficial keratectomy to restore corneal transparency. Thirty days after the second superficial keratectomy, the third eyelid flap was removed. Conjunctivalization of the upper nasal quadrant of the cornea was observed. The axial portion of the cornea was transparent and vision was restored

    A review of antiviral drugs and other compounds with activity against feline herpesvirus type 1

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    Feline herpesvirus type 1 (FHV-1) is a common and important cause of ocular surface disease, dermatitis, respiratory disease, and potentially intraocular disease in cats. Many antiviral drugs developed for the treatment of humans infected with herpesviruses have been used to treat cats infected with FHV-1. Translational use of drugs in this manner ideally requires methodical investigation of their in vitro efficacy against FHV-1 followed by pharmacokinetic and safety trials in normal cats. Subsequently, placebo-controlled efficacy studies in experimentally inoculated animals should be performed followed, finally, by carefully designed and monitored clinical trials in client-owned animals. This review is intended to provide a concise overview of the available literature regarding the efficacy of antiviral drugs and other compounds with proven or putative activity against FHV-1, as well as a discussion of their safety in cats

    Diagnosis and treatment of conjunctival and corneal diseases

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