Complex Risks from Old Urban Waste Landfills: Sustainability Perspective from Iasi, Romania

Landfills continue to represent the most frequent managerial practice for municipal solid wastes and an increasing and complex problem globally. In certain countries, a transition to an open society and free market is superimposed on the transition to sustainability, resulting in even higher complexity of management. This paper proposes an approach for problem-structuring of landfills in complex transitions: sustainability or unsustainability of a management approach is determined by a set of sustainability filters that are defined by sets of indicators and prioritized according the systemic concept of sustainability, which says that economy is embedded in society, which is embedded in nature. The writers exercise this approach with an old landfill in Iasi, Romania, and conclude for unsustainability, because the ecological sustainability filter is not successfully passed. Social and economic sustainability filters are also discussed in relation with the ecological sustainability indicators. The described approach allows a coherent, transdisciplinary synthesis of knowledge scattered across various disciplines, a pervasive problem in landfill management. The case study helps distinguish between generally true and context-dependent aspects.Peer reviewe

Influencia del tamaño de partícula del serrín en las propiedades de los ladrillos de arcilla quemada

This study investigates the effect of adding different size fractions of the same pore forming agent (sawdust) on the material’s compressive strength and heat transfer. The samples were dry pressed and fired at high temperature inside an oven. Phase transformations were evidenced by a combination of differential thermal analysis, thermogravimetry and mass spectrometry (DTA-TGA-MS) and X-ray diffraction (XRD) techniques, in the temperature range of 24-900 ºC. Image analysis (IA) and compression tests were performed to explain the mechanical behaviour of the samples. The thermal conductivity was obtained by using combined photopyroelectric calorimetry (PPE) and lock-in thermography (LIT) techniques. The pressing direction has an impact on the distribution of pores and the heat transfer by conduction.Este estudio investiga el efecto de la adición de diferentes fracciones de tamaño del mismo agente de formación de poros (serrín) sobre la resistencia a la compresión y la transferencia de calor del material. Las muestras fueron presionadas, secadas y cocidas a alta temperatura dentro de un horno. Se identificaron transformaciones de fase mediante el empleo de análisis térmico diferencial, termogravimétrico y espectrometria de masas (DTA-TGA-MS) y técnicas de difracción de rayos X (XRD) en el intervalo de temperatura de 24-9000 C. Se realizaron análisis de imagen (IA) y ensayos de compresión para explicar el comportamiento mecánico de las muestras. La conductividad térmica se obtuvo mediante el uso de técnicas combinadas de calorimetría fotopiroeléctrica (PPE) y termografia de bloqueo (LIT). Se concluye que la dirección de prensado tiene un impacto sobre la distribución de los poros y la transferencia de calor por conducción

A hybrid approach for estimating the drawbead restraining force in sheet metal forming

In order to achieve better part quality in sheet metal forming the rate of the material flow into the die cavity must be efficiently controlled. This control is obtained using a restraining force supplied either by the blankholder tool, drawbeads or both. When the restraining force required is too high, the use of drawbeads is necessary, although excessive blank deformation may be produced. Some other disadvantages such as adjustment difficulties during die try-outs to determine the actual Drawbead Restraining Force (DBRF) may also be encountered. One way to solve these problems and to reduce the number of die try-outs - which are very much time consuming - is to introduce/define accurate enough drawbead concepts. The present study will make use of a method that has been developed using the similitude approach in order to understand the influence of the most important parameters on DBRF and to establish a pre-estimate DBRF theory. Data bases have been developed throughout Explicit Dynamic Finite Element Method (EDFEM) based simulations. The results are compared with experimental data bases provided by Nine (1978) and with the analytical model of Stoughton (1988) results. The average of absolute error with respect to experimental data bases was around 6% and, for the studied cases, the maximum discrepancy was found to be below 11%. For the analytical and experimental cases, the average of absolute error was approximately 5% and, for the studied cases, the maximum error was below 7%. In terms of precision, the predictions derived from this approach are adequate when compared with analytical and experimental results. For this reason, the approach has been validated and accepted as a contribution to STAMPACK®, a commercial explicit dynamic finite element based system for forming processes numerical simulation

SARS-CoV-2 Breakthrough Infections: Incidence and Risk Factors in a Large European Multicentric Cohort of Health Workers.

Background: The research aimed to investigate the incidence of SARS-CoV-2 breakthrough infections and their determinants in a large European cohort of more than 60,000 health workers. Methods: A multicentric retrospective cohort study, involving 12 European centers, was carried out within the ORCHESTRA project, collecting data up to 18 November 2021 on fully vaccinated health workers. The cumulative incidence of SARS-CoV-2 breakthrough infections was investigated with its association with occupational and social-demographic characteristics (age, sex, job title, previous SARS-CoV-2 infection, antibody titer levels, and time from the vaccination course completion). Results: Among 64,172 health workers from 12 European health centers, 797 breakthrough infections were observed (cumulative incidence of 1.2%). The primary analysis using individual data on 8 out of 12 centers showed that age and previous infection significantly modified breakthrough infection rates. In the meta-analysis of aggregated data from all centers, previous SARS-CoV-2 infection and the standardized antibody titer were inversely related to the risk of breakthrough infection (p = 0.008 and p = 0.007, respectively). Conclusion: The inverse correlation of antibody titer with the risk of breakthrough infection supports the evidence that vaccination plays a primary role in infection prevention, especially in health workers. Cellular immunity, previous clinical conditions, and vaccination timing should be further investigated

Determination of Alkali and Halide Monovalent Ion Parameters for Use in Explicitly Solvated Biomolecular Simulations

Alkali (Li+, Na+, K+, Rb+, and Cs+) and halide (F−, Cl−, Br−, and I−) ions play an important role in many biological phenomena, roles that range from stabilization of biomolecular structure, to influence on biomolecular dynamics, to key physiological influence on homeostasis and signaling. To properly model ionic interaction and stability in atomistic simulations of biomolecular structure, dynamics, folding, catalysis, and function, an accurate model or representation of the monovalent ions is critically necessary. A good model needs to simultaneously reproduce many properties of ions, including their structure, dynamics, solvation, and moreover both the interactions of these ions with each other in the crystal and in solution and the interactions of ions with other molecules. At present, the best force fields for biomolecules employ a simple additive, nonpolarizable, and pairwise potential for atomic interaction. In this work, we describe our efforts to build better models of the monovalent ions within the pairwise Coulombic and 6-12 Lennard-Jones framework, where the models are tuned to balance crystal and solution properties in Ewald simulations with specific choices of well-known water models. Although it has been clearly demonstrated that truly accurate treatments of ions will require inclusion of nonadditivity and polarizability (particularly with the anions) and ultimately even a quantum mechanical treatment, our goal was to simply push the limits of the additive treatments to see if a balanced model could be created. The applied methodology is general and can be extended to other ions and to polarizable force-field models. Our starting point centered on observations from long simulations of biomolecules in salt solution with the AMBER force fields where salt crystals formed well below their solubility limit. The likely cause of the artifact in the AMBER parameters relates to the naive mixing of the Smith and Dang chloride parameters with AMBER-adapted Åqvist cation parameters. To provide a more appropriate balance, we reoptimized the parameters of the Lennard-Jones potential for the ions and specific choices of water models. To validate and optimize the parameters, we calculated hydration free energies of the solvated ions and also lattice energies (LE) and lattice constants (LC) of alkali halide salt crystals. This is the first effort that systematically scans across the Lennard-Jones space (well depth and radius) while balancing ion properties like LE and LC across all pair combinations of the alkali ions and halide ions. The optimization across the entire monovalent series avoids systematic deviations. The ion parameters developed, optimized, and characterized were targeted for use with some of the most commonly used rigid and nonpolarizable water models, specifically TIP3P, TIP4PEW, and SPC/E. In addition to well reproducing the solution and crystal properties, the new ion parameters well reproduce binding energies of the ions to water and the radii of the first hydration shells