Subsea salt flows in the Atlantis II Deep and Tethis Deep, Red Sea

In the area of today’s Red Sea, evaporites were widely deposited during the Miocene. Due to the ongoing rifting and seafloor spreading, the evaporites have lost their lateral constraint and started to move downslope. High sediment temperatures near the Red Sea graben and the weak rheology of halite may also favour evaporite movement. However, the deformation mechanism as well as the velocity of these flows is largely unknown. New high-resolution multibeam and seismic data were recorded in March 2011 (P408-2 cruise) within the framework of the project “The Jeddah Transect”, a cooperation between King Abdulaziz University, Saudi-Arabia and GEOMAR, Germany. The data give new insights into evaporite flows in the area of the Atlantis II Deep. This ~400 m deep seafloor depression is located at about 21°N in the central Red Sea graben and is partly filled with hot saline brine (T~68°C, S~270h. The brine-seawater interface at about 2050 mbsl coincides with the depth of a subseafloor salt layer in the seismic reflection data. The rough seafloor morphology of the Atlantis II Deep area is dominated by a sequence of normal faults showing vertical offsets of several hundred meters. However, SW-NE directed lineaments parallel to the seafloor gradient in the south east and possibly north-west of the deep, with typical heights between 20 and 40 m, widths between 300 and 1000 m and lengths exceeding 10 km in places, are interpreted as surface indications of subsurface evaporite flow. The fronts of some of these flows are well rounded, and their occurrence is limited to areas of low seafloor gradients. Generally, the appearance of evaporite flows in the Atlantis II Deep is comparable to salt flows in the Thetis Deep at ~23°N (Mitchell et al., 2010). Furthermore, deformed hemipelagic layers deposited on top of the Miocene evaporites indicate salt movement 60 km off the central rift axis. A second research cruise is planned in March 2012 (RV Pelagia) to obtain more high-resolution seismic data on the morphological structures related to the evaporite flows at 21°N. Additionally, repeated multibeam measurements in the Thetis Deep will constrain the maximum movement rate of the evaporites. Mitchell, N. C. ; Ligi, M. ; Ferrante, V. ; Bonatti, E. ; Rutter, E.: Submarine salt flows in the central Red Sea. In: Geological Society of America Bulletin vol. 122 (2010), Nr. 5-6, pp. 701–71

Liberalism, Human Rights, and Human Dignity

Do international standards regarding human rights require the existence of a liberal regime? This was the thrust of Rhoda Howard and Jack Donnelly’s essay in the September 1986 issue of this Review. Neil Mitchell takes vigorous issue with this contention, arguing first and foremost that Howard and Donnelly have not defined liberalism satisfactorily. Howard and Donnelly present a spirited rejoinder

Electromagnetic and mechanical characterisation of ITER CS-MC conductors affected by transverse cyclic loading, part 1: coupling current loss

The magnetic field generated by a coil acts on the cable which results in a transverse force on the strands. This affects the interstrand contact resistances (Rc), the coupling current loss and current redistribution during field changes. A special cryogenic press has been built to study the mechanical and electrical properties of full-size ITER conductor samples under transverse, mechanical loading. The cryogenic press can transmit a variable (cyclic) force up to 650 kN/m to a conductor section of 400 mm length at 4.2 K. The jacket is partly opened in order to transmit the force directly onto the cable. In addition a superconducting dipole coil provides the magnetic field required to perform magnetisation measurements using pick-up coils. The various Rc's between strands selected from different positions inside the cable have been studied. The coupling loss time constants (nτ) during and after loading are verified for the Nb3Sn, 45 kA, 10 and 13 T, ITER Model Coil conductors. A summary of the results obtained with up to several tens of full loading cycles is presented. A significant decrease of the cable nτ after several cycles is observed. The values of the nτ's are discussed with respect to the Rc measurements and a multiple time constant model (MTC)

IL-17 can be protective or deleterious in murine pneumococcal pneumonia

Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection. The cytokine IL-17 protects against such colonization and vaccines that enhance IL-17 responses to pneumococcal colonization are being developed. The role of IL-17 in host defence against pneumonia is not known. To address this issue, we have utilized a murine model of pneumococcal pneumonia in which the gene for the IL-17 cytokine family receptor, Il17ra, has been inactivated. Using this model, we show that IL-17 produced predominantly from γδ T cells protects mice against death from the invasive TIGR4 strain (serotype 4) which expresses a relatively thin capsule. However, in pneumonia produced by two heavily encapsulated strains with low invasive potential (serotypes 3 and 6B), IL-17 significantly enhanced mortality. Neutrophil uptake and killing of the serotype 3 strain was significantly impaired compared to the serotype 4 strain and depletion of neutrophils with antibody enhanced survival of mice infected with the highly encapsulated SRL1 strain. These data strongly suggest that IL-17 mediated neutrophil recruitment to the lungs clears infection from the invasive TIGR4 strain but that lung neutrophils exacerbate disease caused by the highly encapsulated pneumococcal strains. Thus, whilst augmenting IL-17 immune responses against pneumococci may decrease nasal colonization, this may worsen outcome during pneumonia caused by some strains

The Link between Social Cognition and Self-referential Thought in the Medial Prefrontal Cortex

The medial prefrontal cortex (mPFC) has been implicated in seemingly disparate cognitive functions, such as understanding the minds of other people and processing information about the self. This functional overlap would be expected if humans use their own experiences to infer the mental states of others, a basic postulate of simulation theory. Neural activity was measured while participants attended to either the mental or physical aspects of a series of other people. To permit a test of simulation theory’s prediction that inferences based on self-reflection should only be made for similar others, targets were subsequently rated for their degree of similarity to self. Parametric analyses revealed a region of the ventral mPFC—previously implicated in self-referencing tasks—in which activity correlated with perceived self/other similarity, but only for mentalizing trials. These results suggest that self-reflection may be used to infer the mental states of others when they are sufficiently similar to self.Psycholog

Making the Most of Interim Assessment Data: Lessons from Philadelphia

Under No Child Left Behind, urban school districts have increasingly turned to interim assessments, administered at regular intervals, to help gauge student progress in advance of annual state exams. These assessments have spawned growing debate among educators, assessment experts, and the testing industry: are they worth the significant investment of money and time? In Making the Most of Interim Assessment Data: Lessons from Philadelphia, Research for Action (RFA) weighs in on this issue. The School District of Philadelphia (SDP) was an early adopter of interim assessments, implementing the exams in 2003. Unlike teachers in some other regions, Philadelphia elementary and middle grades teachers rated these 'Benchmark' assessments highly. However, the study found that enthusiasm did not necessarily correlate with higher rates of student achievement. What did predict student success were three factors -- instructional leadership, collective responsibility, and use of the SDP's Core Curriculum. The report underscores the value of investment in ongoing data interpretation that emphasizes teachers' learning within formal instructional communities, such as grade groups of teachers. This research was funded by the Spencer Foundation and the William Penn Foundation

Electromagnetic and mechanical AC loss of an ITER TF model coil conductor (DP4) under transverse cyclic loading

Energising a coil results in a transverse force on the strands pushing the cable towards one side of the jacket. This load causes a transverse compressive strain in strands and in particular in strand crossover points. Besides this, contact surfaces interfere by micro-sliding resulting in friction and anomalous contact resistance behaviour versus force. Two Central Solenoid Model Coil conductors have been tested previously in a cryogenic press and now the experimental results are presented for the Toroidal Field Model Coil (TFMC) conductor (DP4). The press can transmit a variable (cyclic) force of at least 650 kN/m directly to a cable section of 400 mm at 4.2 K. The magnetisation of the conductor and the interstrand resistance (Rc) between various strands inside the cable can be measured by varying pressure. The force on the cable and the displacement are monitored simultaneously in order to determine the effective cable Young's modulus and the mechanical heat generation due to friction and deformation. The mechanical heat generation, the coupling loss time constant n¿ and the Rc of the full-size ITER TFMC conductor have been studied under load up to 40 full loading cycles. The evolution of Rc is comparable to the behaviour found for the CS Model Coil type of conductors. A significant decrease of the cable coupling current time constant, n¿ and mechanical heat generation after cyclic loading is foun