Más sobre el itinerario geográfico en El Criticón de Baltasar Gracián

El objetivo de esta ponencia es aportar nuevos elementos al debate sobre la existencia o no de un referente geográfico en el itinerario del Criticón. Concretamente, desearía: legitimar el principio de una búsqueda de referentes geográficos para los espacios alegóricos del relato; proponer una identificación nueva; y señalar las incidencias de esta localización en la interpretación del Criticón, en lo que se refiere al alcance político de la obra

International consensus (ICON) on treatment of Ménière's disease

Objective: To present the international consensus for recommendations for Ménière's disease (MD) treatment. Methods: Based on a literature review and report of 4 experts from 4 continents, the recommendations have been presented during the 21st IFOS congress in Paris, in June 2017 and are presented in this work. Results: The recommendation is to change the lifestyle, to use the vestibular rehabilitation in the intercritic period and to propose psychotherapy. As a conservative medical treatment of first line, the authors recommend to use diuretics and Betahistine or local pressure therapy. When medical treatment fails, the recommendation is to use a second line treatment, which consists in the intratympanic injection of steroids. Then as a third line treatment, depending on the hearing function, could be either the endolymphatic sac surgery (when hearing is worth being preserved) or the intratympanic injection of gentamicin (with higher risks of hearing loss). The very last option is the destructive surgical treatment labyrinthectomy, associated or not to cochlear implantation or vestibular nerve section (when hearing is worth being preserved), which is the most frequent option

Transperineal magnetic resonance image targeted prostate biopsy versus transperineal template prostate biopsy in the detection of clinically significant prostate cancer.

PURPOSE: Multiparametric magnetic resonance imaging can be used to guide prostate biopsy by targeting biopsies to areas in the prostate at high risk for cancer. We compared the detection of clinically significant and insignificant cancer by transperineal magnetic resonance imaging targeted biopsy and transperineal template guided prostate biopsy. MATERIALS AND METHODS: A total of 182 men with a lesion suspicious for cancer on multiparametric magnetic resonance imaging underwent transperineal magnetic resonance imaging targeted biopsy using a cognitive registration technique, followed by systematic transperineal template guided prostate biopsy. The primary outcome was the detection rate of clinically significant prostate cancer. Clinical significance was defined using maximum cancer core length 4 mm or greater and/or Gleason grade 3 + 4 or greater (University College London definition 2). We secondarily evaluated other commonly used thresholds of clinically significant disease, including maximum cancer core length 6 mm or greater and/or Gleason grade 4 + 3 or greater, maximum cancer core length 3 mm or greater and/or Gleason grade 3 + 4 or greater, and maximum cancer core length 2 or greater mm and/or Gleason grade 3 + 4 or greater. Strategies were statistically compared with the McNemar test. RESULTS: Mean ± SD patient age was 63.3 ± 7.2 years. Median prostate specific antigen was 6.7 ng/ml (IQR 4.7-10.0). Clinically significant cancer was detected by magnetic resonance imaging targeted biopsy and template guided prostate biopsy in 103 (57%) and 113 of the 182 men (62%) (p = 0.174), and clinically insignificant cancer was detected in 17 (9.3%) and 31 (17.0%), respectively (p = 0.024). CONCLUSIONS: Prostate biopsy targeted to suspicious lesions on multiparametric magnetic resonance imaging has encouraging rates of detection of clinically significant cancer while also decreasing the detection rate of clinically insignificant cancer. This is achieved with fewer biopsy cores than for systematic template guided biopsy. Further prospective, multicenter, comparative trials of the performance of targeting strategies are needed to consider magnetic resonance imaging targeted biopsy an alternative to conventional systematic biopsy

Bilan de 25 ans de prospections archéologiques dans le nord de la Sarthe

Après 25 ans de prospection, les observations de terrain ont permis la découverte de 700 entités archéologiques ou sites et une analyse des résultats obtenus peut être proposée. Il y a lieu de distinguer les communes qui ont été entièrement couvertes par les prospections au sol et en aérien, avec celles qui n’ont été que partiellement « explorées ». 400 sites et indices proviennent des 12 communes qui ont été entièrement prospectées auxquelles on peut ajouter la moitié de la commune d’Ancinne..

Commune de Fyé

Cette commune de 1 631 ha a été prospecté à 60 % avec des passages tous les 25-30 m. Au Néolithique, on peut considérer cet espace comme une zone tampon car la densité des concentrations lithiques va en s’amenuisant à l’ouest alors que les implantations des premiers agriculteurs vers l’est (Rouessé-Fontaine, Louvigny, le Saosnois…) sont beaucoup plus nombreuses. La Protohistoire se contente de réoccuper les terres vraisemblablement déjà défrichées. Les gallo-romains ont, quant à eux, établi l..

Commune de Rouessé-Fontaine

La prospection diachronique de Rouessé-Fontaine, commune de 1 248 ha, est fort enrichissante, ceci grâce à l’étendue des surfaces prospectables aux trois-quarts et par les secteurs choisis pour les implantations humaines. Parmi les occupations néolithiques, il faut citer en tout premier lieu le village de Vaux, situé au milieu des ruisseaux, des sources, et à proximité des terres géologiquement riches. Outre le mobilier lithique traditionnel (pointes de flèches à pédoncules, haches et pics, g..

Commune de Chérisay et ses environs

Cherisay, commune de 798,99 ha, apparaît dans les actes des Évêques du Mans en 616, sous le nom de « Charisago ». À part une colline centrale correspondant à l’implantation du bourg actuel, le relief présente les particularités suivantes : plateau en pente douce orienté à l’est, pour la moitié nord ; hauteur plus accentuée au sud ; une crête de grès armoricain barre le territoire à l’ouest, le séparant de l’antique Oisseau. Les voiries ont emprunté de tous temps ces hauteurs rocailleuses ; le..

Livet-en-Saosnois

La prospection au sol de la commune de Livet-en-Saosnois poursuit trois objectifs : • confirmer la densité des occupations anciennes de ce secteur de terrasse haute (notamment aux époques néolithiques, protohistoriques et gallo-romaines), densité observée dans l’étendue des communes voisines de Louvigny et Ancinnes, composées des mêmes sols jurassiques (J 1-2) ; • étudier la nature des liens entretenus entre le territoire de Livet et la forêt de Perseigne à laquelle il est adossé ; • compren..

Are white storks addicted to junk food? Impacts of landfill use on the movement and behaviour of resident white storks (Ciconia ciconia) from a partially migratory population

Background: The migratory patterns of animals are changing in response to global environmental change with many species forming resident populations in areas where they were once migratory. The white stork (Ciconia ciconia) was wholly migratory in Europe but recently guaranteed, year-round food from landfill sites has facilitated the establishment of resident populations in Iberia. In this study 17 resident white storks were fitted with GPS/GSM data loggers (including accelerometer) and tracked for 9.1 ± 3.7 months to quantify the extent and consistency of landfill attendance by individuals during the non-breeding and breeding seasons and to assess the influence of landfill use on daily distances travelled, percentage of GPS fixes spent foraging and non-landfill foraging ranges. Results: Resident white storks used landfill more during non-breeding (20.1 % ± 2.3 of foraging GPS fixes) than during breeding (14.9 % ± 2.2). Landfill attendance declined with increasing distance between nest and landfill in both seasons. During non-breeding a large percentage of GPS fixes occurred on the nest throughout the day (27 % ± 3.0 of fixes) in the majority of tagged storks. This study provides first confirmation of year-round nest use by resident white storks. The percentage of GPS fixes on the nest was not influenced by the distance between nest and the landfill site. Storks travelled up to 48.2 km to visit landfills during non-breeding and a maximum of 28.1 km during breeding, notably further than previous estimates. Storks nesting close to landfill sites used landfill more and had smaller foraging ranges in non-landfill habitat indicating higher reliance on landfill. The majority of non-landfill foraging occurred around the nest and long distance trips were made specifically to visit landfill. Conclusions: The continuous availability of food resources on landfill has facilitated year-round nest use in white storks and is influencing their home ranges and movement behaviour. White storks rely on landfill sites for foraging especially during the non-breeding season when other food resources are scarcer and this artificial food supplementation probably facilitated the establishment of resident populations. The closure of landfills, as required by EU Landfill Directives, will likely cause dramatic impacts on white stork populations

Las primeras traducciones del «Persiles» ante las ambigüedades del Septentrión cervantino a nivel geográfico y religioso: en busca de pistas sobre la temprana recepción de la novela

Más de cuatro siglos tras la primera edición del Persiles, todavía suscita desconcierto su geografía novelesca. Este artículo recorre otra vez su borroso archipiélago septentrional, pero guiado por los primeros traductores del Persiles: los franceses François de Rosset y Vital d’Audiguier (traducciones de 1618); el anónimo autor de la versión inglesa de 1619; el italiano Francesco Ellio (1626); así como Madame Le Givre Du Richebourg, autora de otra traducción francesa más tardía pero también más libre, de 1738.Se propone examinar cómo se habrán traducido (y entonces interpretado) algunas ambigüedades del texto respecto a la geografía nórdica y las cuestiones religiosas: si los traductores fueron tentados, por ejemplo, de identificar lugares ficcionales (como Hibernia o Golandia) con unos territorios reales. Al observar cómo viajó el texto de una lengua a otras, aparecen indicios sobre la temprana recepción de la novela, en cuanto a la cuestión de su verosimilitud y sus relaciones (o no) con los conflictos confesionales y políticos que entonces trastornaban a Europa