Identification of Novel Pesticides for Use against Glasshouse Invertebrate Pests in UK Tomatoes and Peppers

To inform current and future pesticide availability to glasshouse vegetable growers, the current project trialled more than twenty products, including existing industry standards, against four key pests of glasshouse tomatoes and bell peppers. These included experimental conventional chemical pesticides as well as alternative biopesticide and biorational products based on phytochemicals, microbials and physically-acting substances. The results suggest that certain biopesticide products, particularly botanicals, provide good levels of pest control, with the same being true of experimental conventional chemical pesticides not yet recommended for use against these pests on these crops. Efforts are on-going to ensure that results of the current project translate to industry benefit via new pesticide approvals

Implementing a strand of a scalable fault-tolerant quantum computing fabric

Quantum error correction (QEC) is an essential step towards realising scalable quantum computers. Theoretically, it is possible to achieve arbitrarily long protection of quantum information from corruption due to decoherence or imperfect controls, so long as the error rate is below a threshold value. The two-dimensional surface code (SC) is a fault-tolerant error correction protocol} that has garnered considerable attention for actual physical implementations, due to relatively high error thresholds ~1%, and restriction to planar lattices with nearest-neighbour interactions. Here we show a necessary element for SC error correction: high-fidelity parity detection of two code qubits via measurement of a third syndrome qubit. The experiment is performed on a sub-section of the SC lattice with three superconducting transmon qubits, in which two independent outer code qubits are joined to a central syndrome qubit via two linking bus resonators. With all-microwave high-fidelity single- and two-qubit nearest-neighbour entangling gates, we demonstrate entanglement distributed across the entire sub-section by generating a three-qubit Greenberger-Horne-Zeilinger (GHZ) state with fidelity ~94%. Then, via high-fidelity measurement of the syndrome qubit, we deterministically entangle the otherwise un-coupled outer code qubits, in either an even or odd parity Bell state, conditioned on the syndrome state. Finally, to fully characterize this parity readout, we develop a new measurement tomography protocol to obtain a fidelity metric (90% and 91%). Our results reveal a straightforward path for expanding superconducting circuits towards larger networks for the SC and eventually a primitive logical qubit implementation.Comment: 9 pages, 4 main figures, 3 extended data figure

Milky Way demographics with the VVV survey. IV. PSF photometry from almost one billion stars in the Galactic bulge and adjacent southern disk

Accepted for publication in a forthcoming issue of Astronomy & Astrophysics. Reproduced with permission from Astronomy & Astrophysics. © 2018 ESO.Context. The inner regions of the Galaxy are severely affected by extinction, which limits our capability to study the stellar populations present there. The Vista Variables in the Vía Láctea (VVV) ESO Public Survey has observed this zone at near-infrared wavelengths where reddening is highly diminished. Aims. By exploiting the high resolution and wide field-of-view of the VVV images we aim to produce a deep, homogeneous, and highly complete database of sources that cover the innermost regions of our Galaxy. Methods. To better deal with the high crowding in the surveyed areas, we have used point spread function (PSF)-fitting techniques to obtain a new photometry of the VVV images, in the ZY JHK s near-infrared filters available. Results. Our final catalogs contain close to one billion sources, with precise photometry in up to five near-infrared filters, and they are already being used to provide an unprecedented view of the inner Galactic stellar populations. We make these catalogs publicly available to the community. Our catalogs allow us to build the VVV giga-CMD, a series of color-magnitude diagrams of the inner regions of the Milky Way presented as supplementary videos. We provide a qualitative analysis of some representative CMDs of the inner regions of the Galaxy, and briefly mention some of the studies we have developed with this new dataset so far.Peer reviewe

Kif15 functions as an active mechanical ratchet

Kif15 is a kinesin-12 that contributes critically to bipolar spindle assembly in humans. Here we use force-ramp experiments in an optical trap to probe the mechanics of single Kif15 molecules under hindering or assisting loads and in a variety of nucleotide states. Whilst unloaded Kif15 is established to be highly processive, we find that under hindering loads, Kif15 takes <∼10 steps. As hindering load is increased, Kif15 forestep:backstep ratio decreases exponentially, with stall occurring at 6 pN. By contrast, under assisting loads, Kif15 detaches readily and rapidly, even from its AMPPNP state. Kif15 mechanics thus depend markedly on the loading direction. Kif15 interacts with a binding partner, Tpx2, and we show that Tpx2 locks Kif15 to microtubules under both hindering and assisting loads. Overall, our data predict that Kif15 in the central spindle will act as a mechanical ratchet, supporting spindle extension but resisting spindle compression