173 research outputs found

    Prevalence of childhood disability and the characteristics and circumstances of disabled children in the UK : secondary analysis of the Family Resources Survey

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    Background: Robust data on the prevalence of childhood disability and the circumstances and characteristics of disabled children is crucial to understanding the relationship between impairment and social disadvantage. It is also crucial for public policy development aimed at reducing the prevalence of childhood disability and providing appropriate and timely service provision. This paper reports prevalence rates for childhood disability in the United Kingdom (UK) and describes the social and household circumstances of disabled children, comparing these where appropriate to those of non-disabled children. Methods: Data were generated from secondary analysis of the Family Resources Survey, a national UK cross-sectional survey, (2004/5) which had data on 16,012 children aged 0-18 years. Children were defined as disabled if they met the Disability Discrimination Act (DDA) definition (1995 and 2005). Frequency distributions and cross-tabulations were run to establish prevalence estimates, and describe the circumstances of disabled children. To establish the association between individual social and material factors and childhood disability when other factors were controlled for, logistic regression models were fitted on the dependent variable 'DDA defined disability'. Results: 7.3% (CI 6.9, 7.7) of UK children were reported by as disabled according to the DDA definition. Patterns of disability differed between sexes with boys having a higher rate overall and more likely than girls to experience difficulties with physical coordination; memory, concentration and learning; communication. Disabled children lived in different personal situations from their non-disabled counterparts, and were more likely to live with low-income, deprivation, debt and poor housing. This was particularly the case for disabled children from black/minority ethnic/ mixed parentage groups and lone-parent households. Childhood disability was associated with lone parenthood and parental disability and these associations persisted when social disadvantage was controlled for. Conclusion: These analyses suggest that UK disabled children experience higher levels of poverty and personal and social disadvantage than other children. Further research is required to establish accurate prevalence estimates of childhood disability among different black and minority ethnic groups and to understand the associations between childhood disability and lone parenthood and the higher rates of sibling and parental disability in households with disabled children

    Workplace productivity and office type: an evaluation of office occupier differences based on age and gender

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    Purpose Open plan office environments are considered to offer workplace productivity benefits because of the opportunities that they create for interaction and knowledge exchange, but more recent research has highlighted noise, distraction and loss of privacy as significant productivity penalties with this office layout. This study aims to investigate if the purported productivity benefits of open plan outweigh the potential productivity penalties. Design/methodology/approach Previous research suggests that office environments are experienced differently according to the gender and age of the occupier across both open-plan and enclosed configurations. Empirical research undertaken with office occupiers in the Middle East (N=220) led to evaluations to establish the impact different offices had on perceived productivity. Factor analysis was used to establish five underlying components of office productivity. The five factors are subsequently used as the basis for comparison between office occupiers based on age, gender and office type. Findings This research shows that benefits and penalties to workplace productivity are experienced equally across open-plan and enclosed office environments. The greatest impact on perceived workplace productivity however was availability of a variety of physical layouts, control over interaction and the 'downtime' offered by social interaction points. Male occupiers and those from younger generations were also found to consider the office environment to have more of a negative impact on their perceived workplace productivity compared to female and older occupiers. Originality/value The originality of this paper is that it develops the concept of profiling office occupiers with the aim of better matching office provision. This paper aims to establish different occupier profiles based on age, gender and office type. Data analysis techniques such as factor analysis and t-test analysis identify the need for different spaces so that occupiers can choose the most appropriate space to best undertake a particular work task. In addition, it emphasises the value that occupiers place on ‘downtime’ leading to the need for appropriate social space

    Star formation rates in luminous quasars at 2 <z< 3

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    We investigate the relation between star formation rates (M ˙ s M˙s ) and AGN properties in optically selected type 1 quasars at 2 < z < 3 using data from Herschel and the SDSS. We find that M ˙ s M˙s remains approximately constant with redshift, at 300 ± 100 M⊙ yr−1. Conversely, M ˙ s M˙s increases with AGN luminosity, up to a maximum of ∼ 600 M⊙ yr−1, and with C IV FWHM. In context with previous results, this is consistent with a relation between M ˙ s M˙s and black hole accretion rate (M ˙ bh M˙bh ) existing in only parts of the z−M ˙ s −M ˙ bh z−M˙s−M˙bh plane, dependent on the free gas fraction, the trigger for activity, and the processes that may quench star formation. The relations between M ˙ s M˙s and both AGN luminosity and C IV FWHM are consistent with star formation rates in quasars scaling with black hole mass, though we cannot rule out a separate relation with black hole accretion rate. Star formation rates are observed to decline with increasing C IV equivalent width. This decline can be partially explained via the Baldwin effect, but may have an additional contribution from one or more of three factors; Mi is not a linear tracer of L2500, the Baldwin effect changes form at high AGN luminosities, and high C IV EW values signpost a change in the relation between M ˙ s M˙s and M ˙ bh M˙bh . Finally, there is no strong relation between M ˙ s M˙s and Eddington ratio, or the asymmetry of the C IV line. The former suggests that star formation rates do not scale with how efficiently the black hole is accreting, while the latter is consistent with C IV asymmetries arising from orientation effects

    The ATLAS Trigger/DAQ Authorlist, version 1.0

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    This is a reference document giving the ATLAS Trigger/DAQ author list, version 1.0 of 20 Nov 2008

    The ATLAS trigger - high-level trigger commissioning and operation during early data taking

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    The ATLAS experiment is one of the two general-purpose experiments due to start operation soon at the Large Hadron Collider (LHC). The LHC will collide protons at a centre of mass energy of 14~TeV, with a bunch-crossing rate of 40~MHz. The ATLAS three-level trigger will reduce this input rate to match the foreseen offline storage capability of 100-200~Hz. This paper gives an overview of the ATLAS High Level Trigger focusing on the system design and its innovative features. We then present the ATLAS trigger strategy for the initial phase of LHC exploitation. Finally, we report on the valuable experience acquired through in-situ commissioning of the system where simulated events were used to exercise the trigger chain. In particular we show critical quantities such as event processing times, measured in a large-scale HLT farm using a complex trigger menu

    Modeling Seasonal Distribution of Irrawaddy Dolphins (Orcaella brevirostris) in a Transnational Important Marine Mammal Area

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    Fishing activities continue to decimate populations of marine mammals, fish, and their habitats in the coastal waters of the Kep Archipelago, a cluster of tropical islands on the Cambodia-Vietnam border. In 2019, the area was recognized as an Important Marine Mammal Area, largely owing to the significant presence of Irrawaddy dolphins (Orcaella brevirostris). Understanding habitat preferences and distribution aids in the identification of areas to target for monitoring and conservation, which is particularly challenging in data-limited nations of Southeast Asia. Here, we test the hypothesis that accurate seasonal habitat models, relying on environmental data and species occurrences alone, can be used to describe the ecological processes governing abundance for the resident dolphin population of the Kep Archipelago, Cambodia. Leveraging two years of species and oceanographic data—depth, slope, distance to shore and rivers, sea surface temperature, and chlorophyll-a concentration—we built temporally stratified models to estimate distribution and infer seasonal habitat importance. Overall, Irrawaddy dolphins of Kep displayed habitat preferences similar to other populations, and were predominately encountered in three situations: (1) water depths ranging from 3.0 to 5.3 m, (2) surface water temperatures of 27–32°C, and (3) in close proximity to offshore islands (&lt; 7.5 km). With respect to seasonality, statistical tests detected significant differences for all environment variables considered except seafloor slope. Four predictor sets, each with a unique combination of variables, were used to map seasonal variation in dolphin habitat suitability. Models with highest variable importance scores were water depth, pre- and during monsoon season (61–62%), and sea surface temperature, post-monsoon (71%), which suggests that greater freshwater flow during the wet season may alter primary productivity and dolphin prey abundance. Importantly, findings show the majority of areas with highest habitat suitability are not currently surveyed for dolphins and located outside Kep’s Marine Fisheries Management Area. This research confirms the need to expand monitoring to new areas where high-impact fisheries and other human activities operate. Baseline knowledge on dolphin distribution can guide regional conservation efforts by taking into account the seasonality of the species and support the design of tailored management strategies that address transboundary threats to an Important Marine Mammal Area

    Crop Updates 2001 - Lupins

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    This session covers twenty six papers from different authors: INTRODUCTION, 1. Introduction, Dr Mark Sweetingham LUPIN RESEARCH AND INDUSTRY DEVELOPMENT, Agriculture Western Australia VARIETIES 2. Lupin variety performance: Are you making the most of it? Bevan J. Buirchell, Agriculture Western Australia 3. Adaption of restricted-branching lupins in Western Australia, Bob French and Laurie Wahlsten, Agriculture Western Australia 4. Isolated microspore culture of lupin for production of doubled haploids, Dr Janet Wroth, Dr Kirsty Bayliss and A/Prof. Wallace Cowling, Plant Sciences, Faculty of Agriculture, The University of Western Australia NUTRITION 5. Banding manganese fertiliser below the seed increases seed yields of narrow-leafed lupins, R.F. Brennan, Agriculture Western Australia 6. Residual value of manganese fertiliser for lupin grain production, R.F. Brennan, Agriculture Western Australia AGRONOMY 7. Lupin seeding density, Miles Dracup, Agriculture Western Australia, Nick Galwey, University of Western Australia and Bob Thomson, University of Western AustraliaPESTS AND DISEASES 8. Anthracnose in lupins – understanding the risk, Moin Salam, Art Diggle, Geoff Thomas, Mark Sweetinghamand Bill O’Neill, Agriculture Western Australia 9. Implications of the ‘green bridge’ for viral and fungal disease carry-over between seasons, Debbie Thackray, Agriculture Western Australia and Centre for Legumes in Mediterranean Agriculture 10. Insect pest development in WA via the ‘green bridge’, Kevin Walden, Agriculture Western Australia 11. Lupin anthracnose – seed infection thresholds, Geoff Thomas, Agriculture Western Australia 12. Identification and characterisation of resistance genes to Phomopsis blight in narrow-leafed lupin, M. Shankar1, M.W. Sweetingham1&2 and W.A. Cowling1&3 , 1Co-operative Research Centre for Legumes in Mediterranean Agriculture, 2Agriculture Western Australia, 3Plant Sciences 13. Plant disease diagnostics, Dominie Wright and Nichole Burges, Agriculture Western Australia 14. Detection of strains of Phomopsis exhibiting species preference in lupins, M. Shankar, 1Co-operative Research Centre for Legumes in Mediterranean Agriculture and M.W. Sweetingham, Agriculture Western Australia 15. Potential alternate host for the lupin anthracnose pathogen, Geoff Thomasa, Hu’aan Yangb, Mark Sweetinghamab and Ming Pei Youa, aAgriculture Western Australia, bCooperative Research Centre for Legumes in Mediterranean Agriculture WEEDS 16. Wild radish – the implications for our rotations, Dr David Bowran, Centre for Cropping Systems 17. Competitiveness of wild radish in a wheat – lupin rotation, Abul Hashem, Nerys Wilkins, and Terry Piper, Agriculture Western Australia 18. Population explosion and persistence of wild radish in a wheat-lupin rotation, Abul Hashem, Nerys Wilkins, Aik Cheam and Terry Piper, Agriculture Western Australia 19. Inter-row knockdowns for profitable lupins, Paul Blackwell, Agriculture Western Australia, Miles Obst, Mingenew 20. Is it safe to use 2,4-D Ester 80% pre-sowing when furrow sowing lupins? Andrew Sandison, Elders Ltd QUALITY AND MARKET DEVELOPMENT 21. Lupin protein – what we know, Bill O’Neill, Agriculture Western Australia 22. Foliar N application increases grain protein in lupins, Bob French and Laurie Wahlsten, Agriculture Western Australia 23. Can lupin grain protein be increased with Flexi-N? Cameron Weeks, Erin Hasson, Mingenew-Irwin Group and Luigi Moreschi, CSBP futurefarm 24. Putting a value on lupin use in the aquaculture industry: a fishy business? Brett D. Glencross, Fisheries WA, Fremantle Maritime Centre, Fremantle 25. Selection for thinner seed coats and pod walls in lupins, Jon Clements, Centre for Legumes in Mediterranean Agriculture and Miles Dracup, Agriculture Western Australia 26. Assessing the nutritional benefit of Australian sweet lupin (Lupinus angustifolius) in human foods, Ramon Hall (SPIRT PhD scholar), Stuart Johnson, Madeleine Ball, Deakin University, Melbourne, Sofia Sipsas and David Petterson, Agriculture Western Australi

    Herschel-ATLAS: multi-wavelength SEDs and physical properties of 250 μm selected galaxies at z < 0.5

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    We present a pan-chromatic analysis of an unprecedented sample of 1402 250 μm selected galaxies at z < 0.5 ( ) from the Herschel-ATLAS survey. We complement our Herschel 100–500 μm data with UV–K-band photometry from the Galaxy And Mass Assembly (GAMA) survey and apply the magphys energy-balance technique to produce pan-chromatic spectral energy distributions (SEDs) for a representative sample of 250 μm selected galaxies spanning the most recent 5 Gyr of cosmic history. We derive estimates of physical parameters, including star formation rates, stellar masses, dust masses and infrared (IR) luminosities. The typical H-ATLAS galaxy at z < 0.5 has a far-infrared luminosity in the range 1010–1012  L☉ (SFR: 1–50 M☉ yr−1) and thus is broadly representative of normal star-forming galaxies over this redshift range. We show that 250 μm selected galaxies contain a larger mass of dust at a given IR luminosity or star formation rate than previous samples selected at 60 μm from the IRAS. We derive typical SEDs for H-ATLAS galaxies, and show that the emergent SED shape is most sensitive to specific star formation rate. The optical–UV SEDs also become more reddened due to dust at higher redshifts. Our template SEDs are significantly cooler than existing IR templates. They may therefore be most appropriate for inferring total IR luminosities from moderate redshift sub-millimetre selected samples and for inclusion in models of the lower redshift sub-millimetre galaxy populations

    A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1

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    In healthy individuals, the non-classical MHC molecule HLA-G is only expressed on fetal trophoblast cells that invade the decidua during placentation. We show that a significant proportion of HLA-G at the surface of normal human trophoblast cells is present as a disulphide-linked homodimer of the conventional β2m-associated HLA-I complex. HLA-G is a ligand for leukocyte immunoglobulin-like receptors (LILR), which bind much more efficiently to dimeric HLA-G than to conventional HLA-I molecules. We find that a LILRB1-Fc fusion protein preferentially binds the dimeric form of HLA-G on trophoblast cells. We detect LILRB1 expression on decidual myelomonocytic cells; therefore, trophoblast HLA-G may modulate the function of these cells. Co-culture with HLA-G+ cells does not inhibit monocyte-derived dendritic cell up-regulation of HLA-DR and costimulatory molecules on maturation, but did increase production of IL-6 and IL-10. Furthermore, proliferation of allogeneic lymphocytes was inhibited by HLA-G binding to LILRB1/2 on responding antigen-presenting cells (APC). As HLA-G is the only HLA-I molecule that forms β2m-associated dimers with increased avidity for LILRB1, this interaction could represent a placental-specific signal to decidual APC. We suggest that the placenta is modulating maternal immune responses locally in the uterus through HLA-G, a trophoblast-specific, monomorphic signal present in almost every pregnancy
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