2,732 research outputs found
An assessment and forecast highlighting the importance of restructuring and integration in cross-border acquisitions in Poland: An analysis of M&A experts' opinions
This study analyses the importance of restructuring activities and integration in cross-border acquisitions of Polish firms. We find that in comparison to acquisitions in developed economies analogous transactions in Poland are characterized by the particularly high role of retrenchment, positive impact of changes among incumbent managers and the relatively lower role of integration depth. Evidence concerning possible changes of these factors in the future is not unambiguous. Nonetheless, our findings indicate the possibility of their transition as well as its direction. Potential changes are expected to go in the direction of reducing the role of restructuring and increasing the role of integration.Die Studie analysiert die Wichtigkeit von Umstrukturierungsmaßnahmen und der Integration in grenzüberschreitenden Akquisitionen von polnischen Firmen. Wir finden heraus, dass im Vergleich zu Akquisitionen in entwickelten Ländern analoge Transaktionen in Polen Faktoren wie die Einsparung, der positiven Effekt des Auswechselns von amtierenden Managern und die relative schwache Rolle der Integrationstiefe eine große Rolle spielen. Nachweise über mögliche Veränderungen dieser Faktoren in der Zukunft sind nicht mehrdeutig. Nichtsdestotrotz zeigen unsere Ergebnise die Möglichkeit dieser Transition und auch die einzuschlagende Richtung. Potenzielle Änderungen werden in Richtung von der Reduzierung der Rolle der Umstrukturierung und des Verstärkens der Rolle der Integration abzielen
Variation in Sleep Duration and Circadian Phase by Duty Start Time Among Short-Haul Commercial Airline Pilots
Prior studies have confirmed that commercial airline pilots experience circadian phase shifts and short sleep duration following travel with layovers in different time zones. Few studies have examined the impact of early and late starts on the sleep and circadian phase of airline pilots who return to their domicile after each duty period. We recruited 44 pilots (4 female) from a short-haul commercial airline to participate in a study examining sleep and circadian phase over four duty schedules (baseline, early starts, mid-day starts, late starts). Each duty schedule was five days long, separated by three rest days. Participants completed the rosters in the same order. Sleep outcomes were estimated using wrist-borne actigraphy (Actiware Software, Respironics, Bend, OR) and daily sleep diaries. Thirteen participants volunteered to collect urine samples for the assessment of 6-sulfatoxymelatonin (aMT6s). Urine samples were collected in four hourly bins during the day and eight-hourly bins during sleep episodes, for 24 hours immediately following each experimental duty schedule. The aMT6s results were fit to a cosine in order to obtain the acrophase to estimate circadian phase. Univariate statistics were calculated for acrophase changes, schedule start times and sleep times. All statistical analyses were computed using SAS software (Cary, IN).The mean duty start times varied as expected (baseline 10:17 [ 3:50], early starts 5:24 [ 0:30], mid-day starts 13:52 [ 1:20], late starts 16:33 [ 1:33]). Actigraphy-derived sleep duration varied between schedule types, with the shortest average sleep durations occurring during the early starts and night duty. Mean circadian phase was similar during each schedule type (baseline 26:14 [ 3:22], early starts 25:29 [2:13], mid-day starts 26:20 [ 3:16], late starts 25:49 [ 4:28]), but there were wide inter-individual differences in phase shifting from the beginning to the end of the study, with phase shifts ranging from a 5.98 hour phase advance to an 11.34 hour phase delay. Our preliminary findings suggest that early and late starts are associated with reduced sleep duration. The dispersion in inter-individual differences in circadian phase across shifting duty schedules should be further evaluated to determine how schedule-induced phase shifts may affect operational performance
Clinicopathological evaluation of chronic traumatic encephalopathy in players of American football
IMPORTANCE: Players of American football may be at increased risk of long-term neurological conditions, particularly chronic traumatic encephalopathy (CTE).
OBJECTIVE: To determine the neuropathological and clinical features of deceased football players with CTE.
DESIGN, SETTING, AND PARTICIPANTS: Case series of 202 football players whose brains were donated for research. Neuropathological evaluations and retrospective telephone clinical assessments (including head trauma history) with informants were performed blinded. Online questionnaires ascertained athletic and military history.
EXPOSURES: Participation in American football at any level of play.
MAIN OUTCOMES AND MEASURES: Neuropathological diagnoses of neurodegenerative diseases, including CTE, based on defined diagnostic criteria; CTE neuropathological severity (stages I to IV or dichotomized into mild [stages I and II] and severe [stages III and IV]); informant-reported athletic history and, for players who died in 2014 or later, clinical presentation, including behavior, mood, and cognitive symptoms and dementia.
RESULTS: Among 202 deceased former football players (median age at death, 66 years [interquartile range, 47-76 years]), CTE was neuropathologically diagnosed in 177 players (87%; median age at death, 67 years [interquartile range, 52-77 years]; mean years of football participation, 15.1 [SD, 5.2]), including 0 of 2 pre–high school, 3 of 14 high school (21%), 48 of 53 college (91%), 9 of 14 semiprofessional (64%), 7 of 8 Canadian Football League (88%), and 110 of 111 National Football League (99%) players. Neuropathological severity of CTE was distributed across the highest level of play, with all 3 former high school players having mild pathology and the majority of former college (27 [56%]), semiprofessional (5 [56%]), and professional (101 [86%]) players having severe pathology. Among 27 participants with mild CTE pathology, 26 (96%) had behavioral or mood symptoms or both, 23 (85%) had cognitive symptoms, and 9 (33%) had signs of dementia. Among 84 participants with severe CTE pathology, 75 (89%) had behavioral or mood symptoms or both, 80 (95%) had cognitive symptoms, and 71 (85%) had signs of dementia.
CONCLUSIONS AND RELEVANCE: In a convenience sample of deceased football players who donated their brains for research, a high proportion had neuropathological evidence of CTE, suggesting that CTE may be related to prior participation in football.This study received support from NINDS (grants U01 NS086659, R01 NS078337, R56 NS078337, U01 NS093334, and F32 NS096803), the National Institute on Aging (grants K23 AG046377, P30AG13846 and supplement 0572063345-5, R01 AG1649), the US Department of Defense (grant W81XWH-13-2-0064), the US Department of Veterans Affairs (I01 CX001038), the Veterans Affairs Biorepository (CSP 501), the Veterans Affairs Rehabilitation Research and Development Traumatic Brain Injury Center of Excellence (grant B6796-C), the Department of Defense Peer Reviewed Alzheimer’s Research Program (grant 13267017), the National Operating Committee on Standards for Athletic Equipment, the Alzheimer’s Association (grants NIRG-15-362697 and NIRG-305779), the Concussion Legacy Foundation, the Andlinger Family Foundation, the WWE, and the NFL
Aircraft Exceedances Vary According to Time of Day and Workload
The Flight Operational Quality Assurance (FOQA) programs have been implemented in US and Europe to identify anomalous flights based on data recorded on board an aircraft in an effort to improve flight safety. Numerous methods have been developed to support the analysis of FOQA data. However, it is unclear how FOQA data relates to the performance of the pilot. We sought to characterize the frequency and type of flight exceedances extracted from FOQA data during a controlled pilot schedule in order to determine whether patterns of exceedances related to human control of the aircraft would change according to scheduling factors
The permafrost carbon inventory on the Tibetan Plateau : a new evaluation using deep sediment cores
Acknowledgements We are grateful for Dr. Jens Strauss and the other two anonymous reviewers for their insightful comments on an earlier version of this MS, and appreciate members of the IBCAS Sampling Campaign Teams for their assistance in field investigation. This work was supported by the National Basic Research Program of China on Global Change (2014CB954001 and 2015CB954201), National Natural Science Foundation of China (31322011 and 41371213), and the Thousand Young Talents Program.Peer reviewedPostprin
Improvements in data quality for decision support in intensive care
Nowadays, there is a plethora of technology in hospitals and, in particular, in intensive care units. The clinical data produced everyday can be integrated in a decision support system in real-time to improve quality of care of the critically ill patients. However, there are many sensitive aspects that must be taken into account, mainly the data quality and the integration of heterogeneous data sources. This paper presents INTCare, an Intelligent Decision Support System for Intensive Care in real-time and addresses the previous aspects, in particular, the development of an Electronic Nursing Record and the improvements in the quality of monitored data.Fundação para a Ciência e a Tecnologia (FCT
Better Performance on the Psychomotor Vigilance Task Is Associated with Longer Sleep Duration and Lower Self-Reported Sleep Need in the Real World
The psychomotor vigilance task (PVT) is sensitive measure of performance impairment arising from sleep loss and circadian misalignment. Some individuals are able to maintain stable, good performance during laboratory-imposed sleep restriction. It is unclear whether such individuals need less sleep or whether they are more resilient to the effects of sleep loss. We aimed to characterize the relationship between sleep duration and perceived sleep need with PVT performance under real-world conditions
Microwave digestion methods for preparation of platinum ore samples for Icp analysis
The technique of microwave digestion was evaluated as a possible alternative to conventional sample preparation methods for the platinum ores prior to spectroscopic analysis. Microwave energy used with aqua regia in closed vessel provides elevated pressure and rapid heating which significantly reduce digestion time. All analyses were carried out by inductively coupled plasma atomic-emission spectroscopy (ICP-AES). To reduce matrix interferences during analysis, a predigestion step with 50 mL of 1:1 nitric acid was introduced. Both ICP-AES and inductively plasma mass spectroscopy (ICP-MS) were used for analysis of sample extracts. ICP-AES analyses showed improved recoveries of Pd (60-80%) and Pt (30-60%) in only two reference materials SARM7 and NBM-6b. ICP-MS analyses of the reference materials indicate that most PGE recoveries were 85-102%. Os and Au were less efficiently recovered. Relative percent difference in the determination of the more efficiently recovered elements ranged between 1-12%. Additionally PGE extraction with 10% KCN solution was investigated. Sample extracts were analyzed by ICP-MS. Analyses of the cyanide extracts showed similar PGE recoveries to aqua regia digestion for Ir, Pd, Ru, and Rh. Platinum, osmium and gold recoveries were less efficient. (Abstract shortened by UMI.)
- …
