High Purity Pion Beam at TRIUMF

An extension of the TRIUMF M13 low-energy pion channel designed to suppress positrons based on an energy-loss technique is described. A source of beam channel momentum calibration from the decay pi+ --> e+ nu is also described.Comment: 5 page

Study of a Large NaI(Tl) Crystal

Using a narrow band positron beam, the response of a large high-resolution NaI(Tl) crystal to an incident positron beam was measured. It was found that nuclear interactions cause the appearance of additional peaks in the low energy tail of the deposited energy spectrum

Status of the TRIUMF PIENU Experiment

The PIENU experiment at TRIUMF aims to measure the pion decay branching ratio $R={\Gamma}({\pi}^+{\rightarrow}e^+{\nu}_e({\gamma}))/{\Gamma}({\pi}^+{\rightarrow}{\mu}^+{\nu}_{\mu}({\gamma}))$ with precision $<0.1$% to provide a sensitive test of electron-muon universality in weak interactions. The current status of the PIENU experiment is presented.Comment: Talk presented CIPANP2015. 8 pages, LaTeX, 4 eps figure

Improved Search for Heavy Neutrinos in the Decay π→eν\pi\rightarrow e\nu

A search for massive neutrinos has been made in the decay $\pi\rightarrow e^+ \nu$. No evidence was found for extra peaks in the positron energy spectrum indicative of pion decays involving massive neutrinos ($\pi\rightarrow e^+ \nu_h$). Upper limits (90 \% C.L.) on the neutrino mixing matrix element $|U_{ei}|^2$ in the neutrino mass region 60--135 MeV/$c^2$ were set, which are %representing an order of magnitude improvement over previous results

Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate

Mannosidases catalyze the hydrolysis of a diverse range of polysaccharides and glycoconjugates, and the various sequence-based mannosidase families have evolved ingenious strategies to overcome the stereoelectronic challenges of mannoside chemistry. Using a combination of computational chemistry, inhibitor design and synthesis, and X-ray crystallography of inhibitor/enzyme complexes, it is demonstrated that mannoimidazole-type inhibitors are energetically poised to report faithfully on mannosidase transition-state conformation, and provide direct evidence for the conformational itinerary used by diverse mannosidases, including β-mannanases from families GH26 and GH113. Isofagomine-type inhibitors are poor mimics of transition-state conformation, owing to the high energy barriers that must be crossed to attain mechanistically relevant conformations, however, these sugar-shaped heterocycles allow the acquisition of ternary complexes that span the active site, thus providing valuable insight into active-site residues involved in substrate recognition

Search for Free Decay of Negative Pions in Water and Light Materials

We report on a search for the free decay component of pi- stopped in water and light materials. A non-zero value of this would be an indication of anomalous nu_e contamination to the nu_e and nu_mu_bar production at stopped-pion neutrino facilities. No free decay component of pi- was observed in water, Beryllium, and Aluminum, for which upper limits were established at 8.2E-4, 3.2E-3, and 7.7E-3, respectively

Precision Measurement of the π+→e+νe Branching Ratio in the PIENU Experiment

The PIENU experiment at TRIUMF aims to measure the branching ratio of the pion decay modes Rπ=[π+→e+νe(γ)]/[π+→μ+νμ(γ)] with precision of &lt;0.1%. Precise measurement of Rπ provides a stringent test of electron-muon universality in weak interactions. The current status of the PIENU experiment and future prospects are presented