Resonantly phase-matched Josephson junction traveling wave parametric amplifier

We develop a technique to overcome phase-mismatch in Josephson-junction traveling wave parametric amplifiers in order to achieve high gain over a broad bandwidth. Using "resonant phase matching," we design a compact superconducting device consisting of a transmission line with subwavelength resonant inclusions that simultaneously achieves a gain of 20 dB, an instantaneous bandwidth of 3 GHz, and a saturation power of -98 dBm. Such an amplifier is well-suited to cryogenic broadband microwave measurements such as the multiplexed readout of quantum coherent circuits based on superconducting, semiconducting, or nano-mechanical elements as well as traditional astronomical detectors.Comment: 8 pages, 5 figures, with appendice

Nondestructive photon detection using a single rare-earth ion coupled to a photonic cavity

We study the possibility of using single rare-earth ions coupled to a photonic cavity with high cooperativity for performing nondestructive measurements of photons, which would be useful for global quantum networks and photonic quantum computing. We calculate the achievable fidelity as a function of the parameters of the rare-earth ion and photonic cavity, which include the ion's optical and spin dephasing rates, the cavity linewidth, the single-photon coupling to the cavity, and the detection efficiency. We suggest a promising experimental realization using current state-of-the-art technology in Nd:YVO_4

P-67: Dose response antihypertensive efficacy of aliskiren (SPP 100), an orally active renin inhibitor

Aliskiren (SPP 100), an orally active renin inhibitor, has been shown to inhibit the production of angiotensin I and angiotensin II in healthy volunteers. In a pilot study, aliskiren decreased BP in hypertensive patients at daily doses of 75 and 150 mg. In this multi-centre, double-blind, active comparator trial, the dose-dependent effects of aliskiren were evaluated in 226 patients with mild to moderate hypertension. Parallel groups of randomized patients were assessed at the end of a washout period and again after a 4-week treatment period. Treatment consisted of single oral daily doses of aliskiren (37.5, 75, 150 or 300 mg) or of losartan 100 mg once daily. Daytime ambulatory systolic BP was defined as the primary variable of the study. As illustrated in the figure, a clear dose-response curve was observed for the decrease (mean +/- SEM) in daytime ambulatory systolic BP. The mean (SD) change at the end of the 4-week treatment period was -1.3 (9.5) mmHg, -5.5 (10.6) mmHg, -8.5 (10.4) mmHg, -10.5 (10.7) mmHg, and -11.1 (13.4) mmHg for 37.5, 75, 150, and 300 mg aliskiren and 100mg losartan, respectively. Statistically significant lowering occurred with 75, 150 and 300 mg of aliskiren. The daytime ambulatory systolic BP responses to aliskiren doses of 150 and 300 mg were not significantly different from that of 100 mg losartan. Similar results were shown for daytime ambulatory diastolic BP and for night-time ambulatory systolic and diastolic BP. Aliskiren was well tolerated - there was no increase in the number of adverse events with increasing doses of aliskiren, and the safety profile of aliskiren was similar to that of losartan. The results of this dose-ranging study confirm a dose-dependent reduction in BP with aliskiren in mild to moderate hypertension. Additional exploratory studies testing the efficacy and safety of this new renin inhibitor in patients with renal disease and congestive heart failure are currently underwa

Active control of aircraft engine inlet noise using compact sound sources and distributed error sensors

An active noise control system using a compact sound source is effective to reduce aircraft engine duct noise. The fan noise from a turbofan engine is controlled using an adaptive filtered-x LMS algorithm. Single multi channel control systems are used to control the fan blade passage frequency (BPF) tone and the BPF tone and the first harmonic of the BPF tone for a plane wave excitation. A multi channel control system is used to control any spinning mode. The multi channel control system to control both fan tones and a high pressure compressor BPF tone simultaneously. In order to make active control of turbofan inlet noise a viable technology, a compact sound source is employed to generate the control field. This control field sound source consists of an array of identical thin, cylindrically curved panels with an inner radius of curvature corresponding to that of the engine inlet. These panels are flush mounted inside the inlet duct and sealed on all edges to prevent leakage around the panel and to minimize the aerodynamic losses created by the addition of the panels. Each panel is driven by one or more piezoelectric force transducers mounted on the surface of the panel. The response of the panel to excitation is maximized when it is driven at its resonance; therefore, the panel is designed such that its fundamental frequency is near the tone to be canceled, typically 2000-4000 Hz

Photonic Quantum Logic with Narrowband Light from Single Atoms

Increasing control of single photons enables new applications of photonic quantum-enhanced technology and further experimental exploration of fundamental quantum phenomena. Here, we demonstrate quantum logic using narrow linewidth photons that are produced under nearly perfect quantum control from a single ^87Rb atom strongly coupled to a high-finesse cavity. We use a controlled- NOT gate integrated into a photonic chip to entangle these photons, and we observe non-classical correlations between events separated by periods exceeding the travel time across the chip by three orders of magnitude. This enables quantum technology that will use the properties of both narrowband single photon sources and integrated quantum photonics, such as networked quantum computing, narrow linewidth quantum enhanced sensing and atomic memories.Comment: 5 pates, 3 figure