Storing images in warm atomic vapor

Reversible and coherent storage of light in atomic medium is a key-stone of future quantum information applications. In this work, arbitrary two-dimensional images are slowed and stored in warm atomic vapor for up to 30 $\mu$s, utilizing electromagnetically induced transparency. Both the intensity and the phase patterns of the optical field are maintained. The main limitation on the storage resolution and duration is found to be the diffusion of atoms. A techniqueanalogous to phase-shift lithography is employed to diminish the effect of diffusion on the visibility of the reconstructed image

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes

BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders. Here, we examined the relationship between hepatic Mboat7 down-regulation and fat accumulation. METHODS: Hepatic MBOAT7 expression was surveyed in 119 obese individuals and in experimental models. MBOAT7 was acutely silenced by antisense oligonucleotides in C57Bl/6 mice, and by CRISPR/Cas9 in HepG2 hepatocytes. FINDINGS: In obese individuals, hepatic MBOAT7 mRNA decreased from normal liver to steatohepatitis, independently of diabetes, inflammation and MBOAT7 genotype. Hepatic MBOAT7 levels were reduced in murine models of fatty liver, and by hyper-insulinemia. In wild-type mice, Mboat7 was down-regulated by refeeding and insulin, concomitantly with insulin signalling activation. Acute hepatic Mboat7 silencing promoted hepatic steatosis in vivo and enhanced expression of fatty acid transporter Fatp1. MBOAT7 deletion in hepatocytes reduced the incorporation of arachidonic acid into phosphatidylinositol, consistently with decreased enzymatic activity, determining the accumulation of saturated triglycerides, enhanced lipogenesis and FATP1 expression, while FATP1 deletion rescued the phenotype. INTERPRETATION: MBOAT7 down-regulation by hyper-insulinemia contributes to hepatic fat accumulation, impairing phosphatidylinositol remodelling and up-regulating FATP1. FUNDING: LV was supported by MyFirst Grant AIRC n.16888, Ricerca Finalizzata Ministero della Salute RF-2016-02,364,358, Ricerca corrente Fondazione IRCCS Ca\u27 Granda Ospedale Maggiore Policlinico; LV and AG received funding from the European Union Programme Horizon 2020 (No. 777,377) for the project LITMUS- Liver Investigation: Testing Marker Utility in Steatohepatitis . MM was supported by Fondazione Italiana per lo Studio del Fegato (AISF) \u27Mario Coppo\u27 fellowship

Sequence organization of feline leukemis virus DNA in infected cells

A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV. Restriction fragments were ordered by single and double enzyme digests followed by Southern transfer (1) and hybridization with 32P-labeled viral cDNA probes. The restriction map was oriented with respect to the 5' and 3' ends of viral RNA by using a 3' specific hybridization probe. The major form of unintegrated viral DNA found was a 8.7 kb linear DNA molecule bearing a 450 bp direct long terminal redundancy (LTR) derived from both 5' and 3' viral RNA sequences. Minor, circular forms, 8.7 kb and 8.2 kb in length were also detected, the larger one probably containing two adjacent copies of the LTR and the smaller one containing one copy of the LTR. Integrated copies of FeLV are colinear with the unintegrated linear form and contain the KpnI and SmaI sites found in each LTR

Universal Spectra of Coherent Atoms in a Recurrent Random Walk

The probability of a random walker to return to its starting point in dimensions one and two is unity, a theorem first proven by G. Polya. The recurrence probability -- the probability to be found at the origin at a time t, is a power law with a critical exponent d/2 in dimensions d=1,2. We report an experiment that directly measures the Laplace transform of the recurrence probability in one dimension using Electromagnetically Induced Transparency (EIT) of coherent atoms diffusing in a vapor-cell filled with buffer gas. We find a regime where the limiting form of the complex EIT spectrum is universal and only depends on the effective dimensionality in which the random recurrence takes place. In an effective one-dimensional diffusion setting, the measured spectrum exhibits power law dependence over two decades in the frequency domain with a critical exponent of 0.56 close to the expected value 0.5. Possible extensions to more elaborate diffusion schemes are briefly discussed.Comment: 5 pages, 3 figure

Strange quark asymmetry in the nucleon and the NuTeV anomaly

The NuTeV anomaly of a non-universal value of the fundamental parameter sin^2\theta_W in the electroweak theory has been interpreted as an indication for new physics beyond the Standard Model. However, the observed quantity depends on a possible asymmetry in the momentum distributions of strange quarks and antiquarks in the nucleon. This asymmetry occurs naturally in a phenomenologically successful physical model for such parton distributions, which reduces the NuTeV result to only about two standard deviations from the Standard Model.Comment: 4 pages, 5 figures, RevTex4. Updated with new references and extended discussion. v.3: Minor corrections mad

Electric Dipole Moments in the Generic Supersymmetric Standard Model

The generic supersymmetric standard model is a model built from a supersymmetrized standard model field spectrum the gauge symmetries only. The popular minimal supersymmetric standard model differs from the generic version in having R-parity imposed by hand. We review an efficient formulation of the model and some of the recently obtained interesting phenomenological features, focusing on one-loop contributions to fermion electric dipole moments.Comment: 1+7 pages Revtex 3 figures incoporated; talk at NANP'0

A Formulaic Analysis of Samples Taken from the Shahnama of Firdowsi

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Embedded motivational interviewing combined with a smartphone app to increase physical activity in people with sub-acute low back pain: study protocol of a cluster randomised control trial

Background: Motivational Interviewing is an evidence-based, client-centred counselling technique that has been used effectively to increase physical activity, including for people with low back pain. One barrier to implementing Motivational Interviewing in health care settings more broadly is the extra treatment time with therapists. The aim of this paper is to describe the design of a cluster randomised controlled trial evaluating the effect of an intervention that pairs Motivational Interviewing embedded into usual physiotherapy care with a specifically designed app to increase physical activity in people with sub-acute low back pain. Methods: The study is a cluster randomised controlled in which patients aged over 18 years who have sub-acute low back pain (3–12 weeks duration) are recruited from four public hospital outpatient clinics. Based on the recruitment site, participants either receive usual physiotherapy care or the Motivational Interviewing intervention over 6 consecutive weekly outpatient sessions with a specifically designed app designed to facilitate participant-led physical activity behaviour change in between sessions. Outcome measures assessed at baseline and 7 weeks are: physical activity as measured by accelerometer (primary outcome), and pain-related activity restriction and pain self-efficacy (secondary outcomes). Postintervention interviews with physiotherapists and participants will be conducted as part of a process evaluation. Discussion: This intervention, which comprises trained physiotherapists conducting conversations about increasing physical activity with their patients in a manner consistent with Motivational Interviewing as part of usual care combined with a specifically designed app, has potential to facilitate behaviour change with minimal extra therapist time

Endomorphism Semigroups and Lightlike Translations

Certain criteria are demonstrated for a spatial derivation of a von Neumann algebra to generate a one-parameter semigroup of endomorphisms of that algebra. These are then used to establish a converse to recent results of Borchers and of Wiesbrock on certain one-parameter semigroups of endomorphisms of von Neumann algebras (specifically, Type III_1 factors) that appear as lightlike translations in the theory of algebras of local observables.Comment: 9 pages, Late