766 research outputs found
Investigating the roughness effect of biofouling on propeller performance
As a result of the increasing pressure being placed on the marine industry to address ship emissions, regulations to govern the fuel efficiency and efficient operation of ships in the form of the Energy Efficiency Design Index (EEDI) (IMO, 2014) and Energy Efficiency Operation Index (EEOI) (IMO, 2009a) have recently come into force. These have been introduced alongside regulations concerning specific emissions requirements (UNFCCC). Attention has therefore been turned to all aspects of ship design and operation which have impact on their efficiency. In turn, this paper focuses on the effects of biofouling on propeller surfaces highlighting the benefits of reducing biofouling. This subject was the focus of a recently completed EU-Funded FP7 Project entitled FOUL-X-SPEL (2011). This paper investigates the detrimental impacts of biofouling on the performance of a real ship propeller using Computational Fluid Dynamics (CFD) simulations. Initially, the CFD approach used in this study was validated through CFD open-water tests of a propeller. A previously-developed CFD approach for approximating the surface roughness that results from biofouling has then been applied in order to predict the effects on propeller efficiency. The roughness effects of a typical coating and different fouling conditions on the propeller performance were therefore predicted for various advance coefficients Results indicated negative effects of biofouling on the propeller efficiency and the importance of the mitigation of such effects, supporting the importance of informing the industry about the impacts such that they are able to make informed decisions regarding regular propeller maintenance and cleanin
Experimental determination of the roughness functions of marine coatings
The aim of this paper is to determine the roughness functions of different marine coatings, including two novel FOUL-X-SPEL paints and two existing commercial coatings, and two control surfaces, using the overall method of Granville (1987). An extensive series of towing tests of flat plates coated with different antifouling coatings was carried out at the Kelvin Hydrodynamics Laboratory (KHL) of the University of Strathclyde. The tests were designed to examine the as applied drag performances of FOUL-X-SPEL paints and compare them with two existing reference paints and two control surfaces. The surface roughness amplitude parameters of all of the test surfaces were measured using a hull roughness analyser. In total over 150 runs were carried out, including a series of repeat tests designed to quantify the uncertainty in the results. The drag coefficients and roughness function values of each surface were evaluated along with the uncertainty limits
Yield conditions for deformation of amorphous polymer glasses
Shear yielding of glassy polymers is usually described in terms of the
pressure-dependent Tresca or von Mises yield criteria. We test these criteria
against molecular dynamics simulations of deformation in amorphous polymer
glasses under triaxial loading conditions that are difficult to realize in
experiments. Difficulties and ambiguities in extending several standard
definitions of the yield point to triaxial loads are described. Two
definitions, the maximum and offset octahedral stresses, are then used to
evaluate the yield stress for a wide range of model parameters. In all cases,
the onset of shear is consistent with the pressure-modified von Mises
criterion, and the pressure coefficient is nearly independent of many
parameters. Under triaxial tensile loading, the mode of failure changes to
cavitation.Comment: 9 pages, 8 figures, revte
Turner syndrome and associated problems in turkish children: A multicenter study
Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology
Understanding adhesion at as-deposited interfaces from ab initio thermodynamics of deposition growth: thin-film alumina on titanium carbide
We investigate the chemical composition and adhesion of chemical vapour
deposited thin-film alumina on TiC using and extending a recently proposed
nonequilibrium method of ab initio thermodynamics of deposition growth (AIT-DG)
[Rohrer J and Hyldgaard P 2010 Phys. Rev. B 82 045415]. A previous study of
this system [Rohrer J, Ruberto C and Hyldgaard P 2010 J. Phys.: Condens. Matter
22 015004] found that use of equilibrium thermodynamics leads to predictions of
a non-binding TiC/alumina interface, despite the industrial use as a
wear-resistant coating. This discrepancy between equilibrium theory and
experiment is resolved by the AIT-DG method which predicts interfaces with
strong adhesion. The AIT-DG method combines density functional theory
calculations, rate-equation modelling of the pressure evolution of the
deposition environment and thermochemical data. The AIT-DG method was
previously used to predict prevalent terminations of growing or as-deposited
surfaces of binary materials. Here we extent the method to predict surface and
interface compositions of growing or as-deposited thin films on a substrate and
find that inclusion of the nonequilibrium deposition environment has important
implications for the nature of buried interfaces.Comment: 8 pages, 6 figures, submitted to J. Phys.: Condens. Matte
Investigation of Genetic Polymorphisms of CSN1S1 and BLG Genes in Norduz sheep by PCR-RFLP method
This study was undertaken to examine genetic polymorphisms of Alpha-S1 casein (CSN1S1) and β-Lactoglobulin (BLG) genes in Norduz sheep by PCR-RFLP method. In the study, 10 ml blood samples were taken from 102 heads of Norduz sheep into tubes with EDTA. DNA isolation from blood samples was done with ready-made commercial kits. The target DNA region of alpha-s1 casein and beta-lactoglobulin genes was amplified by PCR technique. The obtained PCR patterns were digested with MboII and RsaI restriction enzymes to determine the genotypes of Alpha-S1 casein and β-lactoglobulin genes, respectively. The cut fragments were run on 2% agarose gel electrophoresis and genotypes were determined under UV light. Statistical analysis, after calculating allele and genotype frequencies by direct gene counting method, the distribution of observed and expected genotypic frequencies was determined according to the Hardy-Weinberg Equilibrium, and whether it was compatible with the χ2 test. β-Lactoglobulin AA, AB and BB genotype frequencies were found to be 17.6%, 69.6 and 12.7%, respectively. It was determined that the β-Lactoglobulin gene was not in Hardy-Weinberg Equilibrium. AlphaS1-Casein AA, AC and CC genotype frequencies were determined as 0.0, 2.9 and 97.1%, respectively. The Alpha-S1 casein gene was determined to be in Hardy-Weinberg equilibrium. It was determined that Norduz sheep showed polymorphism in terms of Alpha-S1 Casein and β-Lactoglobulin genes. In conclusion, it was determined that the A allele of the β-Lactoglobulin gene and the AB genotype were more common, the C allele and the CC genotype of the Alpha-S1 casein gene were more common, and the AA genotype was absent in Norduz sheep. It was concluded that it would be useful to investigate the economic effects of genetic polymorphisms of Alpha-S1 casein and β-Lactoglobulin genes on various yield traits in larger Norduz sheep populations
Universal behavior of localization of residue fluctuations in globular proteins
Localization properties of residue fluctuations in globular proteins are
studied theoretically by using the Gaussian network model. Participation ratio
for each residue fluctuation mode is calculated. It is found that the
relationship between participation ratio and frequency is similar for all
globular proteins, indicating a universal behavior in spite of their different
size, shape, and architecture.Comment: 4 pages, 3 figures. To appear in Phys. Rev.
Investigation of calpastatin (CAST) gene polymorphism in Norduz sheep by PCR-RFLP method
The objective of this research was to determine polymorphism in the calpastatin (CAST) gene in a group of 102 Norduz sheep. Polymorphism was identified using the PCR-RFLP technique. The amplified PCR product with the length of 622 bp was digested with restriction enzymes MspI. It was found that the M and N alleles were present in CAST/MspI locus, their frequency being 78.43 and 21.57%, respectively. Homozygous for the M allele (MM) produced two bands of 336 and 286 bp. Three bands of sizes 622, 336 and 286 bp were seen in case of heterozygous genotype (MN), and homozygous for the N allele (NN) showed a 622 bp band only. The frequencies of homozygous MM, heterozygous MN and homozygous NN genotype were 64.7, 27.5 and 7.8%, respectively. The genotype frequency distributions were in Hardy-Weinberg Equilibrium. In conclusion, the current study is the first study on genotyping of the CAST gene in Norduz sheep. The CAST gene was polymorphic in Norduz sheep. In the CAST gene, the predominant allele in the population was M, with a frequency of 78.43%. The MM and MN genotypes represented 92.2% of the genotype frequencies. The MM genotype was the most common, and NN genotype had the lowest genotype frequency. These results also indicate that in order to be used the polymorphism in the exon 1C/1D region of the CAST gene as a biomarker in Norduz sheep, primarily, association studies with economic traits should be performed
Time-Resolved Studies of Stick-Slip Friction in Sheared Granular Layers
Sensitive and fast force measurements are performed on sheared granular
layers undergoing stick-slip motion, along with simultaneous imaging. A full
study has been done for spherical particles with a +-20% size distribution.
Stick-slip motion due to repetitive fluidization of the layer occurs for low
driving velocities. Between major slip events, slight creep occurs that is
variable from one event to the next. The effects of changing the stiffness k
and velocity V of the driving system are studied in detail. The stick-slip
motion is almost periodic for spherical particles over a wide range of
parameters, but becomes irregular when k is large and V is relatively small. At
larger V, the motion becomes smoother and is affected by the inertia of the
upper plate bounding the layer. Measurements of the period T and amplitude A of
the relative motion are presented as a function of V. At a critical value Vc, a
transition to continuous sliding motion occurs that is discontinuous for k not
too large. The time dependence of the instantaneous velocity of the upper plate
and the frictional force produced by the granular layer are determined within
individual slipping events. The force is a multi-valued function of the
instantaneous velocity, with pronounced hysteresis and a sudden drop prior to
resticking. Measurements of vertical displacement reveal a small dilation of
the material (about one tenth of the mean particle size in a layer 20 particles
deep) associated with each slip event. Finally, optical imaging reveals that
localized microscopic rearrangements precede (and follow) each slip event. The
behavior of smooth particles is contrasted with that of rough particles.Comment: 20, pages, 17 figures, to appear in Phys. Rev.
Simulations of the Static Friction Due to Adsorbed Molecules
The static friction between crystalline surfaces separated by a molecularly
thin layer of adsorbed molecules is calculated using molecular dynamics
simulations. These molecules naturally lead to a finite static friction that is
consistent with macroscopic friction laws. Crystalline alignment, sliding
direction, and the number of adsorbed molecules are not controlled in most
experiments and are shown to have little effect on the friction. Temperature,
molecular geometry and interaction potentials can have larger effects on
friction. The observed trends in friction can be understood in terms of a
simple hard sphere model.Comment: 13 pages, 13 figure
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