Classical Bianchi type I cosmology in K-essence theory

We use one of the simplest forms of the K-essence theory and we apply it to the classical anisotropic Bianchi type I cosmological model, with a barotropic perfect fluid modeling the usual matter content and with cosmological constant. The classical solutions for any but the stiff fluid and without cosmological constant are found in closed form, using a time transformation. We also present the solution whith cosmological constant and some particular values of the barotropic parameter. We present the possible isotropization of the cosmological model, using the ratio between the anisotropic parameters and the volume of the universe and show that this tend to a constant or to zero for different cases. We include also a qualitative analysis of the analog of the Friedmann equation.Comment: 15 pages with one figure, accepted in Advances in High Energy Physic

Cosmological Bianchi Class A models in S\'aez-Ballester theory

We use the S\'aez-Ballester (SB) theory on anisotropic Bianchi Class A cosmological model, with barotropic fluid and cosmological constant, using the Hamilton or Hamilton-Jacobi approach. Contrary to claims in the specialized literature, it is shown that the S\'aez-Ballester theory cannot provide a realistic solution to the dark matter problem of Cosmology for the dust epoch, without a fine tunning because the contribution of the scalar field in this theory is equivalent to a stiff fluid (as can be seen from the energy--momentum tensor for the scalar field), that evolves in a different way as the dust component. To have similar contributions of the scalar component and the dust component implies that their past values were fine tunned. So, we reinterpreting this null result as an indication that dark matter plays a central role in the formation of structures and galaxy evolution, having measureable effects in the cosmic microwave bound radiation, and than this formalism yield to this epoch as primigenius results. We do the mention that this formalism was used recently in the so called K-essence theory applied to dark energy problem, in place to the dark matter problem. Also, we include a quantization procedure of the theory which can be simplified by reinterpreting the theory in the Einstein frame, where the scalar field can be interpreted as part of the matter content of the theory, and exact solutions to the Wheeler-DeWitt equation are found, employing the Bianchi Class A cosmological models.Comment: 24 pages; ISBN: 978-953-307-626-3, InTec

gtfB and spaP virulence genes in Streptococcus mutans strains and their relationship with the DMFT index

Universidad de Talca, Chile; Vásquez Ibarra, Sonia; Lobos Gilabert, Olga; Padilla Espinoza, CarlosObjetivo: El propósito de este estudio fue determinar la presencia de genes de virulencia en cepas de Streptococcus mutans (S. mutans) aisladas desde saliva de individuos de diferentes edades y asociarlas con el índice COPD y ceod según corresponda. Material y método: A partir de un total de 120 individuos de ambos sexos, se conformaron 4 grupos de 30 personas, que se separaron de acuerdo con los siguientes rangos etarios: 3-5, 6-9, 12-15 y mayores de 18 años. A cada individuo se le determinó el índice COPD y ceod según correspondiera y se realizó recuento salival de S. mutans. La detección de los genes de virulencia: gtfB y spaP se realizó por reacción en cadena de la polimerasa convencional. Resultados: Se estableció una asociación positiva entre el recuento bacteriano e índice COPD y ceod. El 100% de las cepas aisladas evidenciaron la presencia del gen gtfB y el 63,6% presentaron el gen spaP. No hubo evidencia estadísticamente significativa que relacionará un alto recuento bacteriano e índice COPD y ceod con la mayor presencia de genes que codifican factores de virulencia en cepas de S. mutans. Resumen: Aim: The aim of this study was to determine the presence of gtfB and spaP virulence genes in Streptococcus mutans strains isolated from saliva taken from individuals of different ages. Material and method: A total of 120 individuals of both sexes were studied. They were assigned to one of 4 groups, with 30 individuals in each one, according to age; 3-5, 6-9, 12-15, and older than 18 years old. DMFT (decayed, missing, and filled teeth) and DMFT indexes were determined in each participant, depending on his/her age. S. mutans microbial counts were performed. The gtfB and spaP virulence genes were detected using conventional PCR. Results: A positive association was found between microbial count and DMFT and DMFT indexes. All the isolated strains demonstrated the presence of gtfB, and 63.6% of the strains had spaP genes. No association was found between high bacterial counts or DMFT and DMFT indexes with the presence of genes that code for virulence factors in S. mutans strains

Negative time delay for wave reflection from a one-dimensional semi-harmonic well

It is reported that the phase time of particles which are reflected by a one-dimensional semi-harmonic well includes a time delay term which is negative for definite intervals of the incoming energy. In this interval, the absolute value of the negative time delay becomes larger as the incident energy becomes smaller. The model is a rectangular well with zero potential energy at its right and a harmonic-like interaction at its left.Comment: 6 pages, 5 eps figures. Talk presented at the XXX Workshop on Geometric Methods in Physics, Bialowieza, Poland, 201

Anti-parasitic activity of pelleted sainfoin (Onobrychis viciifolia) against Ostertagia ostertagi and Cooperia oncophora in calves

BACKGROUND: Increasing anthelmintic-resistance in nematodes of ruminants emphasises the need for sustainable parasite control. Condensed tannin-containing legume forages such as sainfoin (Onobrychis viciifolia) have shown promising anthelmintic properties in small ruminants but this has never been explored in cattle. Therefore, our aim was to examine the efficacy of sainfoin against cattle nematodes in vivo. METHODS: Fifteen Jersey male calves (2–4 month-old) were allocated into two groups and fed isoproteic and isoenergetic diets mainly composed of sainfoin pellets (Group SF; n = 9, three pens) or concentrate and grass-clover hay (Group CO; n = 6, two pens). After 16 days of adaptation, all animals were experimentally infected with 10,000 and 66,000 third-stage larvae of Ostertagia ostertagi and Cooperia oncophora, respectively. Egg excretion, blood parameters and bodyweights were recorded throughout the study. Worms were harvested by sieving for quantification and scanning electron microscopy (SEM) 42 days post-infection (dpi) when the calves were necropsied. RESULTS: The number of O. ostertagi adults in the abomasum was reduced by 50 % in Group SF compared with Group CO (P < 0.05). This was further reflected in higher albumin (P < 0.1) and lower pepsinogen levels (P < 0.05) in Group SF at 21 dpi, and structural damage of the worm cuticle could be visualised by SEM. Yet, the nematode egg excretion in Group SF was not significantly different from that of the controls (P > 0.05). Likewise, no statistical difference in total worm burdens of C. oncophora was found between the groups. Weight gains were lower for Group SF (P < 0.05), which may reflect lower digestibility and phosphorus levels in the SF diet, despite similar feed intake at pen-level. CONCLUSIONS: Overall, the effect of sainfoin on abomasal nematodes corroborates results from studies with small ruminants and encourages further investigations of the use of this crop for control of cattle nematodes

Changes in the diet of hake associated with El Niño 1997?1998 in the northern Humboldt Current ecosystem

International audienceHake (Merluccius gayi peruanus) predation plays an important role in the dynamics of the Humboldt Current ecosystem (HCE). Changes in the hake trophic habits associated with physical variability are expected to impact prey populations and to propagate through the food web. Time series (1995?2002) of (a) stomach contents of hake, (b) biomass estimations of fish prey species of hake, and (c) depth of the 15°C isotherm was analysed with the aim of exploring the impacts of El Niño 1997?1998 on the diet of hake. Biomass estimations of fish prey species were used to indicate resource availability, and depth of the 15°C isotherm to represent variability associated with the ENSO cycle in the physical environment of hake. The richness of prey species increased during the months when 15°C isotherm reached its deepest position, supporting the hypothesis of increased biodiversity (tropicalization) of the HCE during El Niño events. An increased variability in stomach fullness of hake was detected after 1999 which could indicate high heterogeneity in the food supply as a consequence of impacts of the warm event in the biotic community structure of the HCE, a physiological impairment of hake or an effect of the abrupt reduction in the mean total length of hake, postulated as a compensatory response to fishery pressure. Hake can be characterized as an opportunist predator according to the observed changes in its diet during 1995?2002. Overall, the diet of hake in the northern HCE exhibited transitory (e.g. increased richness of prey species in the stomach contents) and medium term (e.g. increased variability in feeding activity) responses associated with El Niño 1997?1998, which should be incorporated both in population dynamics and food web analyses

Fortaleciendo los sistemas tradicionales de producción de semilla en los Andes en Perú.

Los cultivos alimenticios en el Perú han estado históricamente asociados a la pequeña agricultura andina, caracterizada por predios muy pequeños (<3ha), tecnificación tradicional y producción destinada principalmente al autoconsumo y una pequeña proporción para la venta y producción de semilla. El Centro Internacional de la Papa (CIP) a través de su programa Papa Andina/INCOPA promovió una serie de innovaciones que han permitido revalorizar la biodiversidad de la papa y organizar cadenas productivas inclusivas para articular a pequeños productores pobres alto andinos a nuevos mercados. Sin embargo, esta innovación generó demanda por semilla de variedades nativas con potencial de mercado, la cual no ha podido ser satisfecha debido a que el sistema formal de semilla no abastece la demanda interna y las variedades nativas no han sido priorizadas por dicho sistema. Como alternativa, los proyectos del CIP como InnovAndes (Junín y Huancavelica) y McKnight (Pasco), están promoviendo esquemas no convencionales como una alternativa flexible para mejorar los sistemas tradicionales de producción de semilla y responder a la demanda de los pequeños productores. En ambos casos, en las comunidades participantes se organizaron comités de gestión de semillas, que fueron capacitados en técnicas de multiplicación de semilla e identificación de plagas para tener a su cargo la producción de semilla básica en campos semilleros e invernaderos empleando la técnica de selección positiva. La capacitación se realizó a través de escuelas de campo de agricultores (ECA) semilleristas. Como resultado de la intervención, del Proyecto McKnight en las comunidades de La Quinua y Quichas (Pasco) se logró reducir en más del 92% la incidencia de virus (PVX y PVS), enfermedades (P. infestans) e insectos (Epitrix spp, y Diabrótica spp) que afectan la calidad de la semilla, lográndose aumentar el rendimiento promedio de tubérculos en 53%. En este proyecto, el comité de gestión de semillas se constituyó como empresa y cuentan con un invernadero de aeroponia para producir semilla prebásicaa bajo costo, habiendo producido hasta la fecha 54,000 tuberculillos de 6 variedades nativas. En el marco del proyecto Innovandes, los productores de Chicche y Pomamanta (Junín) aprendieron la técnica convencional de propagación y multiplicación de semilla pre-básica en sus respectivos invernaderos. En 2011 la producción fue en total 20,574 tuberculillos de variedades nativas con demanda en el mercado, con lo que han constituido un fondo rotatorio de semilla de las variedades Leona y Cceccorani de uso en gastronomía y la industria, respectivamente. Los resultados indican que la producción de semilla pre-básica en combinación con la técnica de selección positiva ayudará a gestar un mercado regional de semilla de calidad, con posibilidades de evolucionar hacia un esquema o modelo no convencional, similar al de semilla de calidad declarada (QDS)

Unusual formations of the free electromagnetic field in vacuum

It is shown that there are exact solutions of the free Maxwell equations (FME) in vacuum allowing an existence of stable spherical formations of the free magnetic field and ring-like formations of the free electric field. It is detected that a form of these spheres and rings does not change with time in vacuum. It is shown that these convergent solutions are the result of an interference of some divergent solutions of FME. One can surmise that these electromagnetic formations correspond to Kapitsa's hypothesis about interference origin and a structure of fireball.Comment: Revtex-file, without figures. To get lournal-pdf-copy with figures contact with [email protected]

Dietary Leucine - An Environmental Modifier of Insulin Resistance Acting on Multiple Levels of Metabolism

Environmental factors, such as the macronutrient composition of the diet, can have a profound impact on risk of diabetes and metabolic syndrome. In the present study we demonstrate how a single, simple dietary factor—leucine—can modify insulin resistance by acting on multiple tissues and at multiple levels of metabolism. Mice were placed on a normal or high fat diet (HFD). Dietary leucine was doubled by addition to the drinking water. mRNA, protein and complete metabolomic profiles were assessed in the major insulin sensitive tissues and serum, and correlated with changes in glucose homeostasis and insulin signaling. After 8 weeks on HFD, mice developed obesity, fatty liver, inflammatory changes in adipose tissue and insulin resistance at the level of IRS-1 phosphorylation, as well as alterations in metabolomic profile of amino acid metabolites, TCA cycle intermediates, glucose and cholesterol metabolites, and fatty acids in liver, muscle, fat and serum. Doubling dietary leucine reversed many of the metabolite abnormalities and caused a marked improvement in glucose tolerance and insulin signaling without altering food intake or weight gain. Increased dietary leucine was also associated with a decrease in hepatic steatosis and a decrease in inflammation in adipose tissue. These changes occurred despite an increase in insulin-stimulated phosphorylation of p70S6 kinase indicating enhanced activation of mTOR, a phenomenon normally associated with insulin resistance. These data indicate that modest changes in a single environmental/nutrient factor can modify multiple metabolic and signaling pathways and modify HFD induced metabolic syndrome by acting at a systemic level on multiple tissues. These data also suggest that increasing dietary leucine may provide an adjunct in the management of obesity-related insulin resistance

Pedometers to enhance physical activity in COPD: a randomised controlled trial

Physical inactivity is a cardinal feature of chronic obstructive pulmonary disease (COPD), and is associated with increased morbidity and mortality. Pedometers, which have been used in healthy populations, might also increase physical activity in patients with COPD. COPD patients taking part in a 3-month individualised programme to promote an increase in their daily physical activity were randomised to either a standard programme of physical activity encouragement alone, or a pedometer-based programme. Assessments were performed by investigators blinded to treatment allocation. Change in average 1-week daily step count, 6-min walking distance (6MWD), modified Medical Research Council scale, St George’s respiratory questionnaire (SGRQ) and COPD assessment test (CAT) were compared between groups. 102 patients were recruited, of whom 97 completed the programme (pedometer group: n=50; control group: n=47); 60.8% were male with a mean±sd age of 68.7±8.5 years, and forced expiratory volume in 1 s (FEV1) 66.1±19.4% and FEV1/forced vital capacity 55.2±9.5%. Both groups had comparable characteristics at baseline. The pedometer group had significantly greater improvements in: physical activity 3080±3254 steps·day−1 versus 138.3±1950 steps·day−1 (p<0.001); SGRQ −8.8±12.2 versus −3.8±10.9 (p=0.01); CAT score −3.5±5.5 versus −0.6±6.6 (p=0.001); and 6MWD 12.4±34.6 versus −0.7±24.4 m (p=0.02) than patients receiving activity encouragement only. A simple physical activity enhancement programme using pedometers can effectively improve physical activity level and quality of life in COPD patients