5,449 research outputs found
Planning as 'market maker': how planning is used to stimulate development in Germany, France and the Netherlands
No abstract available
Exact solutions for equilibrium configurations of charged conducting liquid jets
A wide class of exact solutions is obtained for the problem of finding the
equilibrium configurations of charged jets of a conducting liquid; these
configurations correspond to the finite-amplitude azimuthal deformations of the
surface of a round jet. A critical value of the linear electric charge density
is determined, for which the jet surface becomes self-intersecting, and the jet
splits into two. It exceeds the density value required for the excitation of
the linear azimuthal instability of the round jet. Hence, there exists a range
of linear charge density values, where our solutions may be stable with respect
to small azimuthal perturbations.Comment: 7 pages, 5 figures, to appear in Physical Review
Distinct Types of Fibrocyte Can Differentiate from Mononuclear Cells in the Presence and Absence of Serum
Background: Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulin–like growth factor signalling (IIS) pathway. In the nematode Caenorhabditis elegans, these phenotypes are molecularly linked such that activation of the forkhead transcription factor DAF-16 both extends lifespan and simultaneously increases immunity and stress resistance. It is known that lifespan varies significantly among the Caenorhabditis species but, although DAF-16 signalling is highly conserved, it is unclear whether this phenotypic linkage occurs in other species. Here we investigate this phenotypic covariance by comparing longevity, stress resistance and immunity in four Caenorhabditis species.
Methodology/Principal Findings: We show using phenotypic analysis of DAF-16 influenced phenotypes that among four closely related Caenorhabditis nematodes, the gonochoristic species (Caenorhabditis remanei and Caenorhabditis brenneri) have diverged significantly with a longer lifespan, improved stress resistance and higher immunity than the hermaphroditic species (C. elegans and Caenorhabditis briggsae). Interestingly, we also observe significant differences in expression levels between the daf-16 homologues in these species using Real-Time PCR, which positively correlate with the observed phenotypes. Finally, we provide additional evidence in support of a role for DAF-16 in regulating phenotypic coupling by using a combination of wildtype isolates, constitutively active daf-16 mutants and bioinformatic analysis.
Conclusions: The gonochoristic species display a significantly longer lifespan (p<0.0001) and more robust immune and stress response (p<0.0001, thermal stress; p<0.01, heavy metal stress; p<0.0001, pathogenic stress) than the hermaphroditic species. Our data suggests that divergence in DAF-16 mediated phenotypes may underlie many of the differences observed between these four species of Caenorhabditis nematodes. These findings are further supported by the correlative higher daf-16 expression levels among the gonochoristic species and significantly higher lifespan, immunity and stress tolerance in the constitutively active daf-16 hermaphroditic mutants
Quantum Reciprocity Conjecture for the Non-Equilibrium Steady State
By considering the lack of history dependence in the non-equilibrium steady
state of a quantum system we are led to conjecture that in such a system, there
is a set of quantum mechanical observables whose retarded response functions
are insensitive to the arrow of time, and which consequently satisfy a quantum
analog of the Onsager reciprocity relations. Systems which satisfy this
conjecture can be described by an effective Free energy functional. We
demonstrate that the conjecture holds in a resonant level model of a multi-lead
quantum dot.Comment: References revised to take account of related work on Onsager
reciprocity in mesoscopics by Christen, and in hydrodynamics by Mclennan,
Dufty and Rub
Magnetic hysteresis in Ising-like dipole-dipole model
Using zero temperature Monte Carlo simulations we have studied the magnetic
hysteresis in a three-dimensional Ising model with nearest neighbor exchange
and dipolar interaction. The average magnetization of spins located inside a
sphere on a cubic lattice is determined as a function of magnetic field varied
periodically. The simulations have justified the appearance of hysteresis and
allowed us to have a deeper insight into the series of metastable states
developed during this process.Comment: REVTEX, 10 pages including 4 figure
Unstable Identities: The European Court of Human Rights and the Margin of Appreciation
All legal systems work under a master narrative – the self-conception of most actors of the system itself. A master narrative is a short and simple story and it is the underlying premise upon which any legal system is based. It is a simple story because it paints the system in quick broad brushstrokes and at (most) times is oblivious to the paradoxes within it. Furthermore, a master narrative is important for legitimization purposes because the actors’ legitimacy will depend on their (perceived) conformity with the system’s master narrative. Therefore, legitimacy is self-referential; the yardsticks for a legitimate action are contained within the system’s master narrative, not outside of it. When talking about different international courts it is important to remember that they are embedded within a master narrative that is contextual and contingent and, at different points, more or less contested. This paper explores the question of what happens when the master-narrative is in a period of transition (from a state cantered to a post-national world order) and when the actors’ legitimacy, their interpretative endeavours the very fundamentals are in a state of flux. I use the margin of appreciation discussion as a focal point of describing the conflicting narratives under which the European Court of Human Rights works, narratives in which the different actors (judges, attorneys, NGO activists, government agents) and their consequences in terms of the interpretation of the European Convention on Human Rights
Sonoluminescence and collapse dynamics of multielectron bubbles in helium
Multielectron bubbles (MEBs) differ from gas-filled bubbles in that it is the
Coulomb repulsion of a nanometer thin layer of electrons that forces the bubble
open rather than the pressure of an enclosed gas. We analyze the implosion of
MEBs subjected to a pressure step, and find that despite the difference in the
underlying processes the collapse dynamics is similar to that of gas-filled
bubbles. When the MEB collapses, the electrons inside it undergo strong
accelerations, leading to the emission of radiation. This type of
sonoluminescence does not involve heating and ionisation of any gas inside the
bubble. We investigate the conditions necessary to obtain sonoluminescence from
multielectron bubbles and calculate the power spectrum of the emitted
radiation.Comment: 6 figure
On the stability of general relativistic geometric thin disks
The stability of general relativistic thin disks is investigated under a
general first order perturbation of the energy momentum tensor. In particular,
we consider temporal, radial and azimuthal "test matter" perturbations of the
quantities involved on the plane . We study the thin disks generated by
applying the "displace, cut and reflect" method, usually known as the image
method, to the Schwarzschild metric in isotropic coordinates and to the
Chazy-Curzon metric and the Zipoy-Voorhees metric (-metric) in Weyl
coordinates. In the case of the isotropic Schwarzschild thin disk, where a
radial pressure is present to support the gravitational attraction, the disk is
stable and the perturbation favors the formation of rings. Also, we found the
expected result that the thin disk models generated by the Chazy-Curzon and
Zipoy-Voorhees metric with only azimuthal pressure are not stable under a
general first order perturbationComment: 11 pages, RevTex. Phys Rev D (in press
High-pressure melting behavior of tin up to 105 GPa
The melting curve of Sn initially rises steeply as a function of pressure but exhibits a decrease in slope (dTm/dP) above 40 GPa to become nearly flat above 50 GPa. Previous studies have argued that a body-centered tetragonal (bct) to cubic (bcc) phase transition occurs in this range at room temperature. However, our investigations have shown that the phase behavior is more complex in this region with orthorhombic (bco) splitting of reflections occurring in the x-ray diffraction pattern above 32 GPa and coexisting diffraction signatures of bco and bcc structures are observed between 40 and 70 GPa. Here we have documented the simultaneous presence of bco and bcc reflections up to the melting point, negating the possibility that their coexistence might indicate a kinetically hindered first-order phase transformation. In this paper we have extended the observation of Sn melting relations into the megabar (P>100 GPa) range using the appearance of liquid diffuse scattering in x-ray diffraction patterns and discontinuities during thermal signal processing to diagnose the occurrence of melting. Both techniques yield consistent results that indicate the melting line maintains the same low slope up to the highest pressure examined and does not flatten. The results below approximately 40 GPa agree well with the melting relations produced recently using a multiphase equation of state fitted to available or assumed data. Above this pressure the experimental melting points lie increasingly below the predicted crystal-liquid phase boundary, but above the flat melting from past studies, indicating that the thermodynamic properties of the body-centered “γ”-Sn structure remain to be clarified
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