Abstract 465: Evolution of Cardiovascular Lifestyle Behaviours Occurring in Hypercholesterolemic Patients Concomitantly to the Intake of Phytosterol-supplemented Yoghurt.

Objective: to assess the evolution of cardiovascular lifestyle behaviours in hypercholesterolemic patients occurring concomitantly with changes in their daily intake of phytosterol-supplemented yoghurt (Phyto-SY). METHODS: Nationwide prospective observational study conducted in Spanish and French general practice Each GP proposed lifestyle modification to 5 consecutive patients presenting with hypercholesterolemia, (taking or not hypocholesterolemic drugs) and recommended daily consumption of Phyto-SY. Study design included an inclusion visit, a patient’s self-monitoring assessment after 1 month and a final end-visit after four months. Main evaluation criterion : nutritional lifestyle score. Secondary criteria: Total, LDL and HDL cholesterol, waist circumference, daily walking time. Results: 2376 hypercholesterolemic patients, 56.2 years old ± 11.9 (women 54.8%) were included. Nutritional lifestyle score decreased from 15.4 ± 5.4 to 8.7± 4.0 (p&lt;0,0001), either in never-treated patients (15.3 ± 5.4 to 8.6 ± 3.9; p&lt;0,0001) or in patients treated with hypocholesterolemic drugs (15.5 ± 5.4 to 8.9 ± 4.1; p&lt;0,0001). Total cholesterol decreased 10.6% (&lt;0.0001), HDL-C increased 8.0% (&lt;0.0001), and LDL-C decreased 12.7% (&lt;0.0001). Frequency of walking (&gt;30 min) increased from 59.3% to 78.3% (p&lt;0.0001); by contrast overweight frequency decreased from 22.8% to 17.5% (p&lt;0.0001) and waist circumference from 94.6 ± 13.3 cm to 93.0 ± 12.8 (p&lt;0.0001). Conclusion: Improvement in nutritional lifestyle score, involving regular consumption of Phyto-SY over 4 months was significantly linked to a healthier lifestyle and to beneficial modification of atherogenic lipid profile, thereby reflecting patient empowerment in a “real life” context. </jats:p

Results of the first performance tests of the CMS electromagnetic calorimeter

Performance tests of some aspects of the CMS ECAL were carried out on modules of the "barrel" sub-system in 2002 and 2003. A brief test with high energy electron beams was made in late 2003 to validate prototypes of the new Very Front End electronics. The final versions of the monitoring and cooling systems, and of the high and low voltage regulation were used in these tests. The results are consistent with the performance targets including those for noise and overall energy resolution, required to fulfil the physics programme of CMS at the LHC.European Physical Journal

Reconstruction of the signal amplitude of the CMS electromagnetic calorimeter

The amplitude of the signal collected from the PbWO(4) crystals of the CMS electromagnetic calorimeter is reconstructed by a digital filtering technique. The amplitude reconstruction has been studied with test beam data recorded from a fully equipped barrel supermodule. Issues specific to data taken in the test beam are investigated, and the implementation of the method for CMS data taking is discussed.European Physical Journal