4,495 research outputs found

    Intercultural competence for future leaders of educational technology and its evaluation

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    Demands of globalization today continue to increase pressure for the education of global citizens who preserve the variety and vitality of life. Our transatlantic project has been developing a shared community of graduate students and faculty experts in educational technology across six universities. Evidence of the development of intercultural competence was analyzed from artifacts, self-report, interviews, and surveys. The findings showed that students gained intercultural competence in professional and personal spheres, with openness and flexibility that include acceptance, adaptability, and multiple perspectives. Applications of educational technology served as a bridge to introduce new cultures, knowledge and people to students.Demands of globalization today continue to increase pressure for the education of global citizens who preserve the variety and vitality of life. Our transatlantic project has been developing a shared community of graduate students and faculty experts in educational technology across six universities. Evidence of the development of intercultural competence was analyzed from artifacts, self-report, interviews, and surveys. The findings showed that students gained intercultural competence in professional and personal spheres, with openness and flexibility that include acceptance, adaptability, and multiple perspectives. Applications of educational technology served as a bridge to introduce new cultures, knowledge and people to students

    Monnaie et cycles

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    Ce texte offre un survol des principaux modèles du cycle économique qui ont été développés depuis le début des années 1980 en mettant un accent particulier sur l’incorporation de la monnaie dans le modèle néoclassique de croissance. Il défend le point de vue que la monnaie ne contribue substantiellement aux fluctuations agrégées qu’en incorporant des rigidités nominales au modèle.This is a survey of the main business cycle models that have been developed since the early '80s. It emphasizes the incorporation of money in the neoclassical growth model. It argues that money contributes substantially to aggregate fluctuations only if nominal rigidities are introduced in the model

    CD9, a Major Platelet Cell Surface Glycoprotein, is a ROCA Antigen and Is Expressed in the Nervous System

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    We previously generated a monoclonal antibody (mAb), ROCA1, which binds preferentially to rostral versus caudal sympathetic ganglia and intercostal nerves. Two other mAbs, ROCA2 and B2C11, bind to the same structures but not in rostrocaudal gradients. All three mAbs recognize a 26 kDa cell surface protein. Amino acid sequence data obtained from the affinity purified 26 kDa protein showed some homology with human CD9, a tetraspan protein implicated in intercellular signaling in hematopoietic cells. Using the PCR, we obtained cDNA clones representing the entire rat CD9 coding sequence from sciatic nerve and sympathetic ganglia. ROCA1, ROCA2, and B2C11 each immunoprecipitate a 26 kDa protein from CHO cells stably transfected with one of the clones, demonstrating that the ROCA cell surface antigen is indeed rat CD9. We find that CD9 mRNA is widely expressed, with particularly high levels present in a number of neural tissues. In situ hybridization demonstrates that peripheral neurons and Schwann cells, as well as adrenal chromaffin cells express CD9 mRNA. Consistent with immunoblot analyses showing that, unlike the ROCA1 epitope, the 26 kDa protein is not expressed in a rostrocaudal gradient, we find similar levels of rat CD9 mRNA in rostral and caudal intercostal nerves. In developing postnatal rat sciatic nerve, CD9 mRNA levels are coordinately regulated with the expression of myelin genes. These results provide another example of a cell surface protein expressed by both hematopoietic and neural cells, and suggest a role for CD9 in intercellular signaling in the nervous system

    Nutritional, Bone, and Physical Fitness States of Jockeys in Chronic Repetition of Short-Term Weight Loss

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    Professional jockeys are required to fit their weight, mainly weight loss, for two game days every weekend during racing season which usually lasts 10 months a year in Korea. The repetitive routine weight loss protocol is performed for 4 to 5 days a week include two game days. This situation would have brought some negative effects on the professional jockeys\u27 overall health and physical condition with the relation of their performance. The purpose of the present study was: 1) to examine the weight loss habits of pro-jockeys, and 2) effects of chronic short-term weight loss on nutritional status, bone health, and physical fitness of them. Pro jockeys (n=43) completed a questionnaire for the assessment of weight loss habits. Pro jockeys (n=10, around 12 years of career) were compared with trainee jockeys (n=10, less than 1 years of career) for their nutritional status, bone health, and physical fitness. The nutritional status was measured by a computerized program (CAN Pro 2.0). Bone mineral density was measured by DEXA (Hologic, QDR-4500W, USA). All participants performed grip strength test, standing on one leg with eyes closed test, and side step test for the assessment of physical fitness. According to the result, more than 80% of pro jockeys underwent a routine weight loss process every week, for around 1 kg, within 2 to 3 days prior to the game days by diet mainly and/or exercise/sauna. Around 70% of them reported severe fatigue during the weight loss period. There were no significant differences in nutritional status between two groups. However, they consume average of 1,100 Kcal a day reflecting 21 to 80% of recommended daily consumption during weight loss periods. In bone health, six trainee jockeys and two pro jockeys were diagnosed as osteopenia. One pro jockey was diagnosed as osteoporosis. No significant difference was found in fitness factors between two groups. In conclusion, chronic exposure to short-term weight loss may result in serious health problems especially on bone health. For the jockeys in Korea, balanced diet program and the related education on weight management are strongly required.

    Flexible ultraviolet and ambient light sensor based on nanomaterial network fabricated by using selective and localized wet-chemical reactions

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    We report ZnO nanowire- and TiO_2 nanotube-based light sensors on flexible polymer substrates fabricated by localized hydrothermal synthesis and liquid phase deposition (LPD). This method realized simple and cost-effective in situ synthesis and integration of one-dimensional ZnO and TiO_2 nanomaterials. The fabricated sensor devices with ZnO nanowires and TiO_2 nanotubes show very high sensitivity and quick response to the ultraviolet (UV) and ambient light, respectively. In addition, our direct synthesis and integration method result in mechanical robustness under external loading such as static and cyclic bending because of the strong bonding between the nanomaterial and the electrode. By controlling the reaction time of the LPD process, the Ti/Zn ratio could be simply modulated and the spectral sensitivity to the light in the UV to visible range could be controlled

    Development of a bycatch reduction device (BRD) for shrimp beam trawl using flexible materials

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    This study aimed to design a bycatch reduction device (BRD) for shrimp beam trawl, which is manufactured by flexible materials to reduce bycatch for the gear in the South Sea of Korea. The model test was carried out to understand the shape of the gear in the water and to measure the variation of flow speed due to the BRD in a circulating water channel. Catches were compared between a shrimp beam trawl without BRD (control gear) and others with BRD (treatment gears) in the field. BRDs were two different types in this study. In the case of BRD (a), a square-shaped grid net and a funnel-shaped net were installed in the front part of the cod end to help fish sorting and expelling through the outlet at the bottom. BRD (b) has one more outlet which is added at the upper part of the BRD (a). On the model test, water speed was reduced a little in the gear by installing the BRD. At the results of comparing with a control gear, the bycatch (%) of fish excluding shrimp was reduced between 17 and 68% using BRD (a) and 5 and 66% for BRD (b) respectively. By the signed test of significant level 0.05, the quantity of shrimp catches for BRD (a) was not different in comparison to the control gear but it decreased for the gear installing BRD (b)

    A stochastic model to predict radio interference caused by corona on high voltage transmission systems

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    A stochastic model to predict radio interference fields caused by corona discharges on high voltage transmission lines has been developed. This model is based on corona discharges distributed randomly in time and space;A stochastic model for the corona current induced by corona discharges on power lines is proposed. Based on the proposed corona current model, a rigorous analysis is presented to evaluate the radio interference field caused by corona discharges on the single conductor using the stochastic method. The analysis developed for a single conductor is applied to the three phase transmission line;Most random parameters generated by the stochastic RI analysis are shown to be determined from the existing RI data

    Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway

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    Rgs2, a regulator of G proteins, lowers blood pressure by decreasing signaling through Gαq. Human patients expressing Met-Leu-Rgs2 (ML-Rgs2) or Met-Arg-Rgs2 (MR-Rgs2) are hypertensive relative to people expressing wild-type Met-Gln-Rgs2 (MQ-Rgs2). We found that wild-type MQ-Rgs2 and its mutant, MR-Rgs2, were destroyed by the Ac/N-end rule pathway, which recognizes Nα-terminally acetylated (Nt-acetylated) proteins. The shortest-lived mutant, ML-Rgs2, was targeted by both the Ac/N-end rule and Arg/N-end rule pathways. The latter pathway recognizes unacetylated N-terminal residues. Thus, the Nt-acetylated Ac-MX-Rgs2 (X = Arg, Gln, Leu) proteins are specific substrates of the mammalian Ac/N-end rule pathway. Furthermore, the Ac/N-degron of Ac-MQ-Rgs2 was conditional, and Teb4, an endoplasmic reticulum (ER) membrane-embedded ubiquitin ligase, was able to regulate G protein signaling by targeting Ac-MX-Rgs2 proteins for degradation through their N^α-terminal acetyl group

    ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex

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    ATP-dependent DNA end recognition and nucleolytic processing are central functions of the Mre11/Rad50 (MR) complex in DNA double-strand break repair. However, it is still unclear how ATP binding and hydrolysis primes the MR function and regulates repair pathway choice in cells. Here, Methanococcus jannaschii MR-ATP gamma S-DNA structure reveals that the partly deformed DNA runs symmetrically across central groove between two ATP gamma S-bound Rad50 nucleotide-binding domains. Duplex DNA cannot access the Mre11 active site in the ATP-free full-length MR complex. ATP hydrolysis drives rotation of the nucleotide-binding domain and induces the DNA melting so that the substrate DNA can access Mre11. Our findings suggest that the ATP hydrolysis-driven conformational changes in both DNA and the MR complex coordinate the melting and endonuclease activity.1120Ysciescopu

    Guided instruction with Logo programming and the development of cognitive monitoring strategies among college students

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    As our society changes and becomes more complex, and as new knowledge and technology emerge, the need for teaching students to be independent thinkers and problem solvers increases more rapidly than ever before. Responding to the ever increasing societal demands, educators have sought for proper learning tools and methodologies to improve students\u27 higher-order thinking and problem solving skills. In particular, cognitive monitoring has been a primary concern of educators and cognitive psychologists. Cognitive monitoring has been regarded as one of the most important strategies in efficient thinking and problem solving. Logo programming has been considered a powerful tool to help students develop higher order thinking, an awareness of their thinking processes, and problem solving skills. Unfortunately, little evidence has been collected for the development of cognitive monitoring and problem solving through Logo programming;This research examined the effects of guided instruction with Logo programming on the development of cognitive monitoring strategies among college students. Guided instruction in this study involved three pedagogical elements. First, Logo programming was selected as a particular learning tool to teach cognitive monitoring strategies. Second, an explicit instructional model of cognitive monitoring processes was included in the process of solving Logo problems: decomposing, planning, executing, identifying errors, and debugging. Third, teacher mediated practice of cognitive monitoring activities was facilitated in a Logo programming environment as well as outside of the programming domain;The results of this study demonstrated positive effects of guided instruction with Logo programming on both near transfer and far transfer of cognitive monitoring strategies. The result also indicated that guided instruction contributed most significantly to the development of Logo error identification and debugging skills
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