Comment on "Foundations of quantum mechanics: Connection with stochastic processes"

Recently, Olavo has proposed several derivations of the Schrodinger equation from different sets of hypothesis ("axiomatizations") [Phys. Rev. A 61, 052109 (2000)]. One of them is based on the infinitesimal inverse Weyl transform of a classically evolved phase space density. We show however that the Schrodinger equation can only be obtained in that manner for linear or quadratic potential functions.Comment: 3 pages, no figure

Interoperability and FAIRness through a novel combination of Web technologies

Data in the life sciences are extremely diverse and are stored in a broad spectrum of repositories ranging from those designed for particular data types (such as KEGG for pathway data or UniProt for protein data) to those that are general-purpose (such as FigShare, Zenodo, Dataverse or EUDAT). These data have widely different levels of sensitivity and security considerations. For example, clinical observations about genetic mutations in patients are highly sensitive, while observations of species diversity are generally not. The lack of uniformity in data models from one repository to another, and in the richness and availability of metadata descriptions, makes integration and analysis of these data a manual, time-consuming task with no scalability. Here we explore a set of resource-oriented Web design patterns for data discovery, accessibility, transformation, and integration that can be implemented by any general- or special-purpose repository as a means to assist users in finding and reusing their data holdings. We show that by using off-the-shelf technologies, interoperability can be achieved atthe level of an individual spreadsheet cell. We note that the behaviours of this architecture compare favourably to the desiderata defined by the FAIR Data Principles, and can therefore represent an exemplar implementation of those principles. The proposed interoperability design patterns may be used to improve discovery and integration of both new and legacy data, maximizing the utility of all scholarly outputs

Entropic Dynamics, Time and Quantum Theory

Quantum mechanics is derived as an application of the method of maximum entropy. No appeal is made to any underlying classical action principle whether deterministic or stochastic. Instead, the basic assumption is that in addition to the particles of interest x there exist extra variables y whose entropy S(x) depends on x. The Schr\"odinger equation follows from their coupled dynamics: the entropy S(x) drives the dynamics of the particles x while they in their turn determine the evolution of S(x). In this "entropic dynamics" time is introduced as a device to keep track of change. A welcome feature of such an entropic time is that it naturally incorporates an arrow of time. Both the magnitude and the phase of the wave function are given statistical interpretations: the magnitude gives the distribution of x in agreement with the usual Born rule and the phase carries information about the entropy S(x) of the extra variables. Extending the model to include external electromagnetic fields yields further insight into the nature of the quantum phase.Comment: 29 page

Prognostic Factors and Expression of MDM2 in Patients with Primary Extremity Liposarcoma

OBJECTIVE: The objective of this study was to investigate MDM2 (murine double minute 2) protein expression and evaluate its relationship with some anatomical and pathological aspects, aiming also to identify prognostic factors concerning local recurrence-free survival, metastasis-free survival and overall survival in patients with primary liposarcomas of the extremities. MATERIALS AND METHODS: Of 50 patients with primary liposarcomas of the extremities admitted to a Reference Service, between 1968 and 2004, 25 were enrolled in the study, following eligibility and exclusion criteria. RESULTS: The adverse factors that influenced the risk for local recurrence in the univariant analysis included male sex (P = 0.023), pleomorphic histological subtype (P = 0.027), and high histological grade (P = 0.007). Concerning metastasis-free survival, age less than 50 years (P = 0.040), male sex (P = 0.040), pleomorphic subtype (P < 0.001), and high histological grade (P = 0.003) had a worse prognosis. Adverse factors for overall survival were age under 50 years (P = 0.040), male sex (P = 0.040), pleomorphic subtype (P < 0.001), and high histological grade (P = 0.003). CONCLUSIONS: There was no correlation between immunohistochemically observed MDM2 protein expressions and the anatomical and pathological variables studied. The immunohistochemical expression of MDM2 protein was not considered to have a prognostic value for any of the surviving patients in this study (local recurrence-free survival, metastasis-free survival, or overall survival). The immunoexpression of MDM2 protein was a frequent event in the different subtypes of liposarcomas

Erosive processes study that affecting Pipa beach - RN

The coastal zone of Rio Grande do Norte has great natural beauties, excelling Pipa Beach in the southern region of the state. It is located in the Municipal district of Tibau do Sul and has exuberant cliffs. However, this beach is being affected by erosive processes in conflict with the local tourist activity, which is in expansion. Such fact ally to the economical pressure of the real estate occupation generates significant environmental impacts, once the coastal atmosphere is very delicate and fragile, and any change that reaches it, produces alterations in all the involved natural factors. So, the present work has an objective to characterize the erosive processes in full detail that are affecting central part of Pipa Beach, located between Ponta do Madeiro and Ponta da Pedra do Moleque, in order to subsidize the development of an occupation zoning with base with these erosive processes, in way to minimize the installed conflicts. Field works were accomplished, walking along the whole central part (with approximately 5 km) and photographing active erosive processes, being these presented by sub-part

Open Science in the Developing World: A Collection of Practical Guides for Researchers in Developing Countries

Over the past decade, the open-science movement has transformed the research landscape, although its impact has largely been confined to developed countries. Recently, researchers from developing countries have called for a redesign of open science to better align with their unique contexts. However, raising awareness alone is insufficient—practical actions are required to drive meaningful and inclusive change. In this work, we analyze the opportunities offered by the open-science movement and explore the macro- and micro-level barriers researchers in developing countries face when engaging with these practices. Drawing on these insights and aiming to inspire researchers in developing regions or other resource-constrained contexts to embrace open-science practices, we offer a four-level guide for gradual engagement: (a) foundation, using open resources to build a solid foundation for rigorous research; (b) growth, adopting low-cost, easily implementable practices; (c) community, contributing to open-science communities through actionable steps; and (d) leadership, taking on leadership roles or forming local communities to foster cultural change. We further discuss potential pitfalls of the current open-science practices and call for readaptation of these practices in developing countries’ settings. We conclude by outlining concrete recommendations for future action

Indirect signals of spawning aggregations of three commercial reef fish species on the continental shelf of Bahia, east coast of Brazil

AbstractLutjanus analis (Mutton snapper), Lutjanus jocu(Dog snapper) and Mycteroperca bonaci (Black grouper) are reef fishes of high commercial value, and are among the principal exploited reef resources on the eastern and northeastern coast of Brazil. These species share the habit of forming transient spawning aggregations, predictable in time and space, which leaves them particularly vulnerable. The present study aimed to obtain indirect indicators of periods and places of spawning aggregations for these species, based on the exploratory analysis of available data on commercial catches and fishing efforts in Southern Bahia. Line fishery landings data were monitored in 12 locations in the region, and catch records of Mutton snapper (1320 landings), Dog snapper (654) and Black grouper (1162) were analyzed. A strategy was developed for exploratory analysis of monthly CPUE variation and individual distribution of CPUE per trip. The results showed the occurrence of aggregations in 26 specific sites, with values of relative abundance far above the annual mean, during spring/summer and autumn/winter. The occurrence of these anomalous catches was validated with the fishermen responsible for respective fishing trips. Additional studies are needed to confirm spawning activity at these sites. Analysis of inter-annual variation suggests a decreasing trend in relative abundance of Black grouper and Mutton snapper, possibly associated with unregulated fishing of spawning aggregations