Anti-seizure activity of flower extracts of Nepeta bractaeta in Swiss albino mice

Epilepsy is a neurological disorder characterized by unprovoked, recurring seizures that disrupts the nervous system and can cause mental and physical dysfunction. Based on the ethno pharmacological information of the plant, the methanolic and aqueous extracts of the flowers of Nepeta bractaeta was evaluated for its antiepileptic activity. The methanolic and aqueous extracts of the flowers of Nepeta bracteata were observed for their antiepileptic activity by increased current Electroshock seizures (ICES) test and Pentylenetetrazole (PTZ) test using Swiss albino mice. Both the extracts showed significant activity in ICES and PTZ induced convulsions in comparison to control. In ICES model, NBAE at higher dose showed 16.7 % and NBME at higher dose showed 33.3 % protection against seizure and in PTZ model, NBME at higher dose showed 33.3 % protection against seizure. From the experiments performed, it can be said that Nepeta bractaeta does possess anticonvulsant property

What is in the Qur’an? Message of the Qur’an in Simple English

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Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice

The aim of the present study was to evaluate the anticonvulsant effect of whole plant extracts of Melissa parviflora using MES and PTZ induced seizures models. The dried whole plant was subjected to extraction in methanol and water. The extracts were subjected to phytochem-ical tests and the carbohydrate, flavonols, coumarins, glycosides and steroid were found to be present. The methanolic and aqueous extracts of the plant of Melissa parviflora were observed for their anticonvulsant activity by Maximal Electroshock seizures (MES) test and Pentylene-tetrazole (PTZ) test using Swiss albino mice. Both the extracts showed significant activity in MES and PTZ induced convulsions in comparison to control. From the literature surveys as well experiments performed, it can be said that Melissa parviflora does pose anticonvulsant property

The Other Senses: Preeti Monga. Roli Books, New Delhi, 2012, 228 pages, Paperback, ₹335

The word autobiography was coined by William Taylor in 1797 in The Monthly Review. This genre maps the recollection of truth, episodes, thoughts and experiences in the writer’s life. However, an autobiography coming from a disabled person encompasses much more than life experiences, as disability aggravates the challenges faced by a disabled individual. A. V. S. Jayaannapurna states that the “onset of 21st century brought to limelight the dreams and ambitions of individual,” and people began to express their subjectivity. This gave the individual a “spiritual space of freewill,” which Jayaannapurna describes as a “retrieval into self” (28). A psychologist can use the work as a guide to the writer’s mind to understand how disability and the dominant discourses about it may have direct or indirect bearing on the writer’s mind. Disability autobiography acts as an effective way of counter-discourse. It challenges the dominant ableist perceptions of that disability narrative that have contributed to portraying the negative somatic experiences in literature. It unveils or illuminates various issues that beset people with anomalous bodies, like human rights violations, stigma, and social and financial barriers. According to Causer, people who returned from wars and life-threatening diseases like polio and breast cancer spurred the autobiographical writings in such a way that nothing like this had happened before (1997). Until the 1950s, disability narratives were scant; whatever literature on disability was available was written by non-disabled writers based on their limited second-hand knowledge derived from myths, fiction and medical treatises. “The testimony of disabled people includes gritty accounts of their pain and daily humiliations — a sure sign of the rhetoric of realism” (Siebers 65). Autobiographical writing by disabled writers can inspire many disabled people to come out of their closets to share and assert their identity with pride. People, for a long time, relied on information about disability either in medical science or literary works, which was highly biased and heuristic. According to Thomas Causer, misrepresentation of disabled people could also be the cause of the lack of writing by the disabled about themselves. Thus, it becomes imperative for the marginalised to come up with transgressive autobiographical writing (Causer 5)

Prophetic Ethics of Inclusion and Conflict Resolution: A Neo-Traditionalist Interpretation of the Sirah

In an era marked by escalating religious intolerance and social fragmentation, the ethical legacy of the Prophet Muhammad (Sirah) offers a compelling yet underexplored framework for promoting peaceful coexistence. Despite its rich content, contemporary discourse often marginalises the inclusive and reconciliatory dimensions of the Prophet’s life. This study aims to examine how neo-traditionalist Muslim scholars—particularly from the West and the Indian subcontinent—interpret the Sirah to address issues of social inclusiveness and conflict resolution. Employing a qualitative descriptive method, this research integrates content analysis, thematic exploration, and comparative interpretation. It focuses on key historical events such as Hilf al-Fudul, the Constitution of Medina, the migration to Abyssinia, the Treaty of Hudaybiyyah, and the Conquest of Makkah. The findings show that neo-traditionalist scholars present a contextual and ethical reading of the Sirah that aligns classical Islamic values with modern challenges. This study contributes to the growing field of peace studies in Islam by reviving the Prophet’s ethical model as a viable framework for interfaith harmony, minority rights, and conflict transformation in pluralistic societies

COPING WITH CANCER OF THE LUNG: PSYCHOLOGICAL ADAPTATION AND RESILIENCE PATHWAYS

Lung cancer poses not just serious physical obstacles but also considerable emotional suffering, affecting patients’ mental well-being and overall quality of life. The diagnosis frequently provokes strong emotional responses such as fear, anxiety, and sorrow, further intensified by stigma and changes to identity. Psychological adjustment the manner in which individuals emotionally and cognitively adapt to the truths of their condition is essential for effective coping. Resilience, which is the capacity to sustain or recover psychological health in the face of challenges, is crucial for promoting positive adaptation to lung cancer. This review compiles existing insights on the coping mechanisms and resilience approaches used by lung cancer patients. Adaptive coping strategies like cognitive reframing, solving problems, and obtaining social support assist in reducing distress and enhancing emotional regulation. Factors that protect, such as robust social connections, spirituality, and previous coping experiences, enhance resilience. Therapeutic approaches, particularly cognitive-behavioral therapy, mindfulness-based stress reduction, and meaning-centered psychotherapy, additionally boost patients’ ability to handle psychological difficulties and maintain hope. Healthcare professionals play a crucial role in promoting psychological adjustment and resilience through compassionate communication, regular mental health assessments, and coordinated psychosocial assistance                     Peer Review History: Received 6 June 2025;   Reviewed 10 July 2025; Accepted 21 August; Available online 15 September 2025 Academic Editor: Dr. Nuray Arı, Ankara University, Turkiye, [email protected] Reviewers: Dr. Eyassu Mathewos, School of public health, college of health sciences and medicine, Wolaita Soddo university- P.O. Box 158, Wolaita Soddo, Ethiopia.    Dr. Fátima Morales Marín, University of Murcia, Spain, [email protected]