Significant enhancement of ferromagnetism in Zn1−x_{1-x}Crx_{x}Te doped with iodine as an n-type dopant

The effect of additional doping of charge impurities was investigated in a ferromagnetic semiconductor Zn$_{1-x}$Cr$_{x}$Te. It was found that the doping of iodine, which is expected to act as an n-type dopant in ZnTe, brought about a drastic enhancement of the ferromagnetism in Zn$_{1-x}$Cr$_{x}$Te while the grown films remained electrically insulating. In particular, at a fixed Cr composition of x = 0.05, the ferromagnetic transition temperature Tc increased up to 300K at maximum due to the iodine doping from Tc = 30K of the undoped counterpart, while the ferromagnetism disappeared due to the doping of nitrogen as a p-type dopant. The observed systematic correlation of ferromagnetism with the doping of charge impurities of both p- and n-type, suggesting a key role of the position of Fermi level within the impurity d-state, is discussed on the basis of the double exchange interaction as a mechanism of ferromagnetism in this material.Comment: 5 figures, to be published in Phys. Rev. Let

Issues for application of virtual microscopy to cytoscreening, perspectives based on questionnaire to Japanese cytotechnologists

To clarify the issues associated with the applications of virtual microscopy to the daily cytology slide screening, we conducted a survey at a slide conference of cytology. The survey was conducted specifically to the Japanese cytology technologists who use microscopes on a routine basis. Virtual slides (VS) were prepared from cytology slides using NanoZoomer (Hamamatsu Photonics, Japan), which is capable of adjusting focus on any part of the slide. A total of ten layers were scanned from the same slides, with 2 micrometer intervals. To simulate the cytology slide screening, no marker points were created. The total data volume of six slides was approximately 25 Giga Bytes. The slides were stored on the Windows 2003 Server, and were made accessible on the web to the cytology technologists. Most cytotechnologists answered "Satisfied" or "Acceptable" to the VS resolution and drawing speed, and "Dissatisfied" to the operation speed. To the ten layered focus, an answer "insufficient" was slightly more frequent than the answer "sufficient", while no one answered "fewer is acceptable" or "no need for depth". As for the use of cytology slide screening, answers "usable, but requires effort" and "not usable" were about equal in number. In a Japanese cytology meeting, a unique VS system has been used in slide conferences with markings to the discussion point for years. Therefore, Japanese cytotechnologists are relatively well accustomed to the use of VS, and the survey results showed that they regarded VS more positively than we expected. Currently, VS has the acceptable resolution and drawing speed even on the web. Most cytotechnologists regard the focusing capability crucial for cytology slide screening, but the consequential enlargement of data size, longer scanning time, and slower drawing speed are the issues that are yet to be resolved

Controlling keywords and their positions in text generation

One of the challenges in text generation is to control generation as intended by a user. Previous studies have proposed to specify the keywords that should be included in the generated text. However, this is insufficient to generate text which reflect the user intent. For example, placing the important keyword beginning of the text would helps attract the reader's attention, but existing methods do not enable such flexible control. In this paper, we tackle a novel task of controlling not only keywords but also the position of each keyword in the text generation. To this end, we show that a method using special tokens can control the relative position of keywords. Experimental results on summarization and story generation tasks show that the proposed method can control keywords and their positions. We also demonstrate that controlling the keyword positions can generate summary texts that are closer to the user's intent than baseline. We release our code

Platelets Strongly Induce Hepatocyte Proliferation with IGF-1 and HGF In Vitro

Background. It is well known that platelets have athrombotic effect. However, platelets play an importantrole not only in hemostasis but also in woundhealing and tissue regeneration. Platelets have beenreported to accumulate in the liver and promote liverregeneration after an extended hepatectomy, but themechanism is unclear. The present study was designedto clarify the mechanism by which plateletshave a direct proliferative effect on hepatocytes invitro.Materials and methods. Hepatocytes obtained frommale BALB/c mice by collagenase digestion and immortalizedhepatocytes (TLR2) were used. To elucidatethe mechanism of the proliferative effect of platelets,DNA synthesis of hepatocytes was measuredunder various conditions and the related cellular signalswere analyzed. Chromatographic analysis wasalso performed to clarify which elements of plateletshave mitogenic activity.Results. DNA synthesis significantly increased in thehepatocytes cultured with platelets (P < 0.001). However,when the platelets and hepatocytes were separated,the platelets did not have a proliferative effect.Whole disrupted platelets, the supernatant fraction,and fresh isolated platelets had a similar proliferativeeffect, while the membrane fraction did not. After theaddition of platelets, both Akt and extracellularsignal-regulated kinases ERK1/2 were activated, butextracellular signal-regulated kinase STAT3 was not activated. Some mitogenic fractions were obtainedfrom the platelet extracts by gel exclusion chromatography;the fractions were rich in hepatocyte growthfactor and IGF-1.Conclusions. Direct contact between platelets andhepatocytes was necessary for the proliferative effect.The direct contact initiated signal transduction involvedin growth factor activation. Hepatocyte growthfactor, vascular endothelial growth factor, and insulin-like growth factor-1, rather than platelet-derivedgrowth factor, mainly contributed to hepatocyteproliferation

Spatial resolved high-energy particle diagnostic system using time-of-flight neutral particle analyzer in Large Helical Device

The time-of-flight-type neutral particle analyzer has an ability of horizontal scanning from 40 to 100° of the pitch angle. The information from the spatially resolved energy spectrum gives not only the ion temperature but also the information of the particle confinement and the electric field in plasmas. We have been studying the energy distributions at various magnetic configurations in the neutral beam injection (NBI) plasma. The spatially resolved energy spectra can be observed during long discharges of the NBI plasma by continuous scanning of the neutral particle analyzer. The shape of spectra is almost similar from 44° to 53°. However, the spectra from 55° are strongly varied. They reflect the injection pitch angle of the beam. The pitch angle scanning experiment during the long discharge of NBI plasma has also been made under the reversal of the magnetic field direction. NBI2 becomes counter injected with the reversal. We can easily observe the difference between co- and counter injections of NBI. During the electron cyclotron heating in the low-density plasma for the formation of the internal thermal barrier, large neutral particle increase or decease can be observed. The degree of the increase/decrease depends on the energy and the density. The reason for the variation of the particle flux is that the orbit of the trapped particle changes due to the electric field formed by the strong electron cyclotron heating