20 research outputs found

    Systematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts

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    Effect of sublethal concentrations of some pesticides on the growth and survival of the fingerlings of the African catfish - Heteroclarias" (hybrid)

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    Fingerlings of "Heteroclarias" (hybrid) were exposed to sublethal concentrations of thiodon (Organophosphate), Malathion (Organophosphate ), and carbaryl (organocarbamide) for a period of 21 days in a static bioassay. The rate of feeding, food conversion and the efficiency of absorption and conversion decreased with increasing concentrations of the pesticides. Protein, carbohydrate and lipid  contents of muscle, liver, gill and intestine in "Heleroclarias" also decreased when the fish were exposed to maximum sublethal concentrations of the pesticides. A comparative analysis of the efficacy of the three pesticides reveals that the growth rate of "Heleroclariase" was drastically reduced on exposure to thiodon Pesticides.Key Words: "Hateroclarrias" Pesticides, sublethal Growth and survival

    Perianesthetic Management of Laparoscopic Kidney Surgery

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    Laparoscopic kidney surgery is commonly used for living donor, partial, and total tumor nephrectomy. The successful emergence of laparoscopic technique was justified by the many benefits offered such as reduced blood loss, tissue trauma, pain, and hospital stay. However, this comes at the expense of physiologic changes and complications secondary to pneumoperitoneum, surgical technique, and patient positioning with significant challenges in anesthetic management. A variety of laparoscopic approaches (transperitoneal, retroperitoneal, hand-assisted, robotic) are used with some having advantages over others. The kidneys are particularly sensitive to hemodynamic changes and pneumoperitoneum. Controversies in perioperative fluid administration exist. New modalities for postoperative pain control have been suggested. Laparoscopic kidney surgery is associated with multiple physiologic changes and adverse events but offers advantages of reduced postoperative pain, faster recovery, and shorter hospital stay. Understanding these physiologic changes and related anesthetic considerations is key for safe patient outcome
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