10 research outputs found

    Measurement of the total cross section and ρ -parameter from elastic scattering in pp collisions at √s=13 TeV with the ATLAS detector

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    In a special run of the LHC with β⋆=2.5 km, proton–proton elastic-scattering events were recorded at s√=13 TeV with an integrated luminosity of 340 μb−1 using the ALFA subdetector of ATLAS in 2016. The elastic cross section was measured differentially in the Mandelstam t variable in the range from −t=2.5⋅10−4 GeV2 to −t=0.46 GeV2 using 6.9 million elastic-scattering candidates. This paper presents measurements of the total cross section σtot, parameters of the nuclear slope, and the ρ-parameter defined as the ratio of the real part to the imaginary part of the elastic-scattering amplitude in the limit t→0. These parameters are determined from a fit to the differential elastic cross section using the optical theorem and different parameterizations of the t-dependence. The results for σtot and ρ are σtot(pp→X)=104.7±1.1 mb ,ρ=0.098±0.011. The uncertainty in σtot is dominated by the luminosity measurement, and in ρ by imperfect knowledge of the detector alignment and by modelling of the nuclear amplitude.publishedVersio

    A Novel Adverse Event of Nusinersen Treatment: Thrombocytosis

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    PubMedID: 31520312[No abstract available

    The effect of Thrombocytopenia on outcome in critically ill children

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    Objective: Thrombocytopenia is common in pediatric intensive care unit. We aimed to investigate thrombocytopenia and risk factors associated with mortality in the pediatric intensive care unit. Design: One year hospital records were investigated retrospectively. Setting: Present study was performed in the pediatric intensive care unit in Çukurova University, Faculty of Medicine. Patients and participants: A total of 94 patients, 50 (53.2 %) boys and 44 girls (46.8%), were included in this study. The median age was 24 months with a range from 1 to 240 months. Thrombocytopenia was defi ned as platelet counts <150x109/L. PRISM II score, mechanical ventilation (MV), use of central venous (CVC) or arterial catheters (AC), presence or absence of sepsis, coagulopathy, hemorrhage and receiving of transfusion were recorded at the time of admission. White blood cell count (WBC), aspartate aminotransferase (AST), alanin aminotransferase (ALT), total protein, albumin/globulin ratio, blood urea nitrogen (BUN), serum creatinine (Cr), total bilirubin, C reactive protein (CRP), procalcitonin (PCT) and lactate were recorded. Measurements and results: The incidence of thrombocytopenia was 59.57%. MV, CVC, coagulopathy, hemorrhage and transfusion were found to be signifi cant factors for thrombocytopenia. Leukocytosis and leucopenia were signifi cant in thrombocytopenic patients (p=0.024). Increased ALT, AST, BUN, total bilirubin and decreased total protein levels signifi cantly were related to thrombocytopenia. Hospital mortality rate was 37.2%. There was a signifi cant association between mortality and the presence of MV, CVC and AC. Sepsis, coagulopathy, hemorrhage and transfusion had strong correlation with mortality. Increased ALT, AST, BUN, bilirubin, PCT, lactate and decreased total protein levels were related to the mortality. Conclusions: The present study suggested that thrombocytopenia could be related to mortality and an indicator of poor prognosis in the pediatric intensive care unit. Therefore thrombocytopenia-associated risk factors should be closely followed up by physicians in critically ill children

    Prevalence of Childhood Affective disorders in Turkey: An epidemiological study

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    Aim: To determine the prevalence of affective disorders in Turkey among a representative sample of Turkish population. Methods: This study was conducted as a part of the “The Epidemiology of Childhood Psychopathology in Turkey” (EPICPAT-T) Study, which was designed by the Turkish Association of Child and Adolescent Mental Health. The inclusion criterion was being a student between the second and fourth grades in the schools assigned as study centers. The assessment tools used were the K-SADS-PL, and a sociodemographic form that was designed by the authors. Impairment was assessed via a 3 point-Likert type scale independently rated by a parent and a teacher. Results: A total of 5842 participants were included in the analyses. The prevalence of affective disorders was 2.5 % without considering impairment and 1.6 % when impairment was taken into account. In our sample, the diagnosis of bipolar disorder was lacking, thus depressive disorders constituted all the cases. Among depressive disorders with impairment, major depressive disorder (MDD) (prevalence of 1.06%) was the most common, followed by dysthymia (prevalence of 0.2%), adjustment disorder with depressive features (prevalence of 0.17%), and depressive disorder-NOS (prevalence of 0.14%). There were no statistically significant gender differences for depression. Maternal psychopathology and paternal physical illness were predictors of affective disorders with pervasive impairment. Conclusion: MDD was the most common depressive disorder among Turkish children in this nationwide epidemiological study. This highlights the severe nature of depression and the importance of early interventions. Populations with maternal psychopathology and paternal physical illness may be the most appropriate targets for interventions to prevent and treat depression in children and adolescents. © 201

    Emulating the impact of additional proton–proton interactions in the ATLAS simulation by presampling sets of inelastic Monte Carlo events

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    © 2022, The Author(s).The accurate simulation of additional interactions at the ATLAS experiment for the analysis of proton–proton collisions delivered by the Large Hadron Collider presents a significant challenge to the computing resources. During the LHC Run 2 (2015–2018), there were up to 70 inelastic interactions per bunch crossing, which need to be accounted for in Monte Carlo (MC) production. In this document, a new method to account for these additional interactions in the simulation chain is described. Instead of sampling the inelastic interactions and adding their energy deposits to a hard-scatter interaction one-by-one, the inelastic interactions are presampled, independent of the hard scatter, and stored as combined events. Consequently, for each hard-scatter interaction, only one such presampled event needs to be added as part of the simulation chain. For the Run 2 simulation chain, with an average of 35 interactions per bunch crossing, this new method provides a substantial reduction in MC production CPU needs of around 20%, while reproducing the properties of the reconstructed quantities relevant for physics analyses with good accuracy.FONDECYTMillennium Institute on Immunology and ImmunotherapyNucleus projec

    Search for exotic decays of the Higgs boson into b b ̄ and missing transverse momentum in pp collisions at √s = 13 TeV with the ATLAS detector

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    A search for the exotic decay of the Higgs boson (H) into a bb ̄ resonance plus missing transverse momentum is described. The search is performed with the ATLAS detector at the Large Hadron Collider using 139 fb−1 of pp collisions at s = 13 TeV. The search targets events from ZH production in an NMSSM scenario where H → χ~20χ~10, with χ~20→aχ~10, where a is a light pseudoscalar Higgs boson and χ~1,20 are the two lightest neutralinos. The decay of the a boson into a pair of b-quarks results in a peak in the dijet invariant mass distribution. The final-state signature consists of two leptons, two or more jets, at least one of which is identified as originating from a b-quark, and missing transverse momentum. Observations are consistent with Standard Model expectations and upper limits are set on the product of cross section times branching ratio for a three-dimensional scan of the masses of the χ~20, χ~10 and a boson. [Figure not available: see fulltext.
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