53 research outputs found
Metabolomic investigation of regional brain tissue dysfunctions induced by global cerebral ischemia
Neonatal MK-801 treatment differentially alters the effect of adolescent or adult MK-801 challenge on locomotion and PPI in male and female rats
Clinical Characteristics and Pharmacological Treatment of Individuals With and Without Intellectual Disability in Pre-trial Assessment-A Population-Based Study
Crimes and sentences in individuals with intellectual disability in a forensic psychiatric context: a register-based study
Crimes and sentences in individuals with intellectual disability in a forensic psychiatric context : a register-based study
Aims: To study associations between intellectual disability (ID) and sexual and violent offending among individuals subject to pre-trial forensic psychiatric assessment. To investigate sentences following pre-trial forensic psychiatric assessment in offenders with and without ID.Methods: A population-based observational study using data from pre-trial forensic psychiatric assessments in Sweden (1997-2013), the Swedish National Crime Register and several other Swedish national registers. The study population consisted of 7450 offenders (87% men, 13% women) who were subject to forensic psychiatric assessment in 1997-2013, of whom 481 (6.5%) were clinically assessed as having ID.Results: ID offenders were more likely than non-ID offenders to have a sexual crime as an index crime [26.2 v. 11.5%, adjusted odds ratio (OR) 2.7, 95% confidence interval (CI) 2.02-3.58] as well as previous convictions regarding sexual offending (10.4 v. 5.6%, adj OR 2.3, 95% CI 1.70-3.12). These associations were restricted to male offenders; sexual offending was uncommon among women. Comorbid attention-deficit hyperactivity disorder reduced the association between ID and sexual offending (adj OR 2.7 v. 3.1, p = 0.017), while comorbid autism spectrum disorder had no significant influence on the association (adj OR 2.7 v. 3.0, p = 0.059). Violent crime was equally common among ID and non-ID offenders. Offenders with ID were more likely than non-ID offenders to be sentenced to forensic psychiatric care or community sanctions and measures (such as probation, conditional sentences or fines) than to prison; however, 15% of individuals who received an ID diagnosis during the forensic psychiatric assessment were sentenced to prison. Previous criminal convictions, concurrent antisocial personality disorders and substance use disorders were associated with a higher probability of a prison sentence among offenders with ID.Conclusions: Sexual crime is overrepresented among offenders with ID compared to offenders with other mental disorders than ID in forensic psychiatric contexts. ID offenders become subject to forensic psychiatric care and forensic psychiatric services need evidence-based treatment programmes for offenders with ID. In addition, there is a need for early intervention strategies suitable for disability services and special education schools, in order to address the complex needs of individuals with ID and prevent sexual and violent offending.</p
Pelatihan deteksi dini penyakit tidak menular pada kader Posbindu di wilayah kerja Puskesmas Sekip Kota Palembang
Secara global, WHO (World Health Organization) memperkirakan penyakit tidak menular menyebabkan sekitar 71% dari jumlah kematian di seluruh dunia. Data tahun 2018 di Indonesia menunjukkan kenaikan prevalensi penyakit tidak menular seperti kanker, stroke, penyakit ginjal kronik, diabetes melitus dan hipertensi disbanding lima tahun sebelumnya. Saat ini Kementerian Kesehatan RI sudah melaksanakan program deteksi dini dan pencegahan penyakit tidak menular di masyarakat dengan melakukan kegiatan promotif, preventif, kuratif dan rehabilitatif bagi individu dan masyarakat melalui Posbindu PTM di sekolah, tempat kerja, lapas/rutan, terminal, kampung nelayan. Pelatihan dilakukan oleh tim FK UNSRI sebagai kegiatan pengabdian kepada masyarakat, dengan peserta berjumlah 10 kader Puskemas Sekip dan 12 orang dari FK UNSRI. Tujuan pelatihan yaitu peserta mampu melakukan pengelolaan dan pelaksanaan Posbindu Penyakit Tidak Menular (PTM). Materi yang diberikan dengan metoda ceramah, tanya jawab, diskusi,praktek keterampilan yaitu memberikan pengetahuan tentang PTM, Posbindu PTM, memberikan kemampuan & keterampilan dalam memantau faktor resiko PTM serta konseling. Terdapat peningkatan nilai posttest yang signifikan dibanding pretest, yang berarti ada peningkatan pengetahuan dan keterampilan deteksi dini faktor risiko PTM. Kegiatan ini menginiasiasi terbentuknya Posbindu PTM Institusi FK Unsri.</jats:p
Ischemia induces short- and long-term remodeling of synaptic activity in the hippocampus
Infant Rat Model of the Shaken Baby Syndrome: Preliminary Characterization and Evidence for the Role of Free Radicals in Cortical Hemorrhaging and Progressive Neuronal Degeneration
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