Probing the internal magnetic field of slowly pulsating B-stars through g modes

We suggest that high-order g modes can be used as a probe of the internal magnetic field of SPB (slowly pulsating B) stars. The idea is based on earlier work by the authors which analytically investigated the effect of a vertical magnetic field on p and g modes in a plane-parallel isothermal stratified atmosphere. It was found that even a weak field can significantly shift the g-mode frequencies -- the effect increases with mode order. In the present study we adopt the classical perturbative approach to estimate the internal field of a 4 solar mass SPB star by looking at its effect on a low-degree ($l=1$) and high-order ($n=20$) g mode with a period of about 1.5 d. We find that a polar field strength of about 110 kG on the edge of the convective core is required to produce a frequency shift of 1%. Frequency splittings of that order have been observed in several SPB variables, in some cases clearly too small to be ascribed to rotation. We suggest that they may be due to a poloidal field with a strength of order 100 kG, buried in the deep interior of the star.Comment: 4 pages, 2 figures (to appear in Astronomy & Astrophysics

On a mechanism for enhancing magnetic activity in tidally interacting binaries

We suggest a mechanism for enhancing magnetic activity in tidally interacting binaries. We suppose that the deviation of the primary star from spherical symmetry due to the tidal influence of the companion leads to stellar pulsation in its fundamental mode. It is shown that stellar radial pulsation amplifies torsional Alfv{\'e}n waves in a dipole-like magnetic field, buried in the interior, according to the recently proposed swing wave-wave interaction (Zaqarashvili 2001). Then amplified Alfv{\'e}n waves lead to the onset of large-scale torsional oscillations, and magnetic flux tubes arising towards the surface owing to magnetic buoyancy diffuse into the atmosphere producing enhanced chromospheric and coronal emission.Comment: Accepted in Ap

Asteroseismic Theory of Rapidly Oscillating Ap Stars

This paper reviews some of the important advances made over the last decade concerning theory of roAp stars.Comment: 9 pages, 5 figure

Challenge of Pigs with Classical Swine Fever Viruses after C-Strain Vaccination Reveals Remarkably Rapid Protection and Insights into Early Immunity

Pre-emptive culling is becoming increasingly questioned as a means of controlling animal diseases, including classical swine fever (CSF). This has prompted discussions on the use of emergency vaccination to control future CSF outbreaks in domestic pigs. Despite a long history of safe use in endemic areas, there is a paucity of data on aspects important to emergency strategies, such as how rapidly CSFV vaccines would protect against transmission, and if this protection is equivalent for all viral genotypes, including highly divergent genotype 3 strains. To evaluate these questions, pigs were vaccinated with the Riemser® C-strain vaccine at 1, 3 and 5 days prior to challenge with genotype 2.1 and 3.3 challenge strains. The vaccine provided equivalent protection against clinical disease caused by for the two challenge strains and, as expected, protection was complete at 5 days post-vaccination. Substantial protection was achieved after 3 days, which was sufficient to prevent transmission of the 3.3 strain to animals in direct contact. Even by one day post-vaccination approximately half the animals were partially protected, and were able to control the infection, indicating that a reduction of the infectious potential is achieved very rapidly after vaccination. There was a close temporal correlation between T cell IFN-γ responses and protection. Interestingly, compared to responses of animals challenged 5 days after vaccination, challenge of animals 3 or 1 days post-vaccination resulted in impaired vaccine-induced T cell responses. This, together with the failure to detect a T cell IFN-γ response in unprotected and unvaccinated animals, indicates that virulent CSFV can inhibit the potent antiviral host defences primed by C-strain in the early period post vaccination

Reduced Lentivirus Susceptibility in Sheep with TMEM154 Mutations

Visna/Maedi, or ovine progressive pneumonia (OPP) as it is known in the United States, is an incurable slow-acting disease of sheep caused by persistent lentivirus infection. This disease affects multiple tissues, including those of the respiratory and central nervous systems. Our aim was to identify ovine genetic risk factors for lentivirus infection. Sixty-nine matched pairs of infected cases and uninfected controls were identified among 736 naturally exposed sheep older than five years of age. These pairs were used in a genome-wide association study with 50,614 markers. A single SNP was identified in the ovine transmembrane protein (TMEM154) that exceeded genome-wide significance (unadjusted p-value 3×10−9). Sanger sequencing of the ovine TMEM154 coding region identified six missense and two frameshift deletion mutations in the predicted signal peptide and extracellular domain. Two TMEM154 haplotypes encoding glutamate (E) at position 35 were associated with infection while a third haplotype with lysine (K) at position 35 was not. Haplotypes encoding full-length E35 isoforms were analyzed together as genetic risk factors in a multi-breed, matched case-control design, with 61 pairs of 4-year-old ewes. The odds of infection for ewes with one copy of a full-length TMEM154 E35 allele were 28 times greater than the odds for those without (p-value<0.0001, 95% CI 5–1,100). In a combined analysis of nine cohorts with 2,705 sheep from Nebraska, Idaho, and Iowa, the relative risk of infection was 2.85 times greater for sheep with a full-length TMEM154 E35 allele (p-value<0.0001, 95% CI 2.36–3.43). Although rare, some sheep were homozygous for TMEM154 deletion mutations and remained uninfected despite a lifetime of significant exposure. Together, these findings indicate that TMEM154 may play a central role in ovine lentivirus infection and removing sheep with the most susceptible genotypes may help eradicate OPP and protect flocks from reinfection