974 research outputs found
P10. Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T cell and B cell responses but improves clinical efficacy in a murine pancreatic carcinoma model
Natural Disaster, Crime, and Narratives of Disorder: The 1861 Mendoza Earthquake and Argentina’s Ruptured Social and Political Faults
Social scientists studying natural disasters have generally found an absence of panic, a decrease in crime, and survivors working together to find basic necessities in the days and weeks after a catastrophe. By contrast, political and military authorities implement measures such as martial law to prevent chaos and lawlessness threatening private property. The media amplifies narratives of disorder, creating the perception of uncontrolled masses wantonly committing crimes in a disaster’s aftermath. Historians study natural disasters to view political, social, economic, and cultural structures stripped of their everyday veneer. The 1861 earthquake that destroyed the provincial capital of Mendoza in western Argentina provides an opportunity to examine narratives of disorder in newspapers and in survivor accounts that highlighted rampant looting and attributed these actions to rural peoples and the popular masses. Reports from the earthquake’s aftermath reflected the political conflicts between the hegemonic urban center of Buenos Aires and the interior provinces of Argentina, as well as the social divisions between urban elites and the lower classes. Judicial and criminal records from Mendoza, however, showed a decrease in crime after the earthquake, as well as rates of theft and robbery similar to those before the catastrophe, contradicting popular accounts of pervasive lawlessness
Aftershocks: Earthquakes and Popular Politics in Latin America
Es reseña de:
Aftershocks: earthquakes and popular politics in Latin America
Jürgen Buchenau (ed. lit.), Lyman L. Johnson (ed. lit.)
Albuquerque : University of New Mexico Press, 200
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Rhythm in the speech of a person with right hemisphere damage: Applying the pairwise variability index
Although several aspects of prosody have been studied in speakers with right hemisphere damage (RHD), rhythm remains largely uninvestigated. This study compares the rhythm of an Australian English speaker with right hemisphere damage (due to a stroke, but with no concomitant dysarthria) to that of a neurologically unimpaired individual. The speakers' rhythm is compared using the pairwise variability index (PVI) which allows for an acoustic characterization of rhythm by comparing the duration of successive vocalic and intervocalic intervals. A sample of speech from a structured interview between a speech and language therapist and each participant was analysed. Previous research has shown that speakers with RHD may have difficulties with intonation production, and therefore it was hypothesized that there may also be rhythmic disturbance. Results show that the neurologically normal control uses a similar rhythm to that reported for British English (there are no previous studies available for Australian English), whilst the speaker with RHD produces speech with a less strongly stress-timed rhythm. This finding was statistically significant for the intervocalic intervals measured (t(8) = 4.7, p < .01), and suggests that some aspects of prosody may be right lateralized for this speaker. The findings are discussed in relation to previous findings of dysprosody in RHD populations, and in relation to syllable-timed speech of people with other neurological conditions
Assessing the Health of Richibucto Estuary with the Latent Health Factor Index
The ability to quantitatively assess the health of an ecosystem is often of
great interest to those tasked with monitoring and conserving ecosystems. For
decades, research in this area has relied upon multimetric indices of various
forms. Although indices may be numbers, many are constructed based on
procedures that are highly qualitative in nature, thus limiting the
quantitative rigour of the practical interpretations made from these indices.
The statistical modelling approach to construct the latent health factor index
(LHFI) was recently developed to express ecological data, collected to
construct conventional multimetric health indices, in a rigorous quantitative
model that integrates qualitative features of ecosystem health and preconceived
ecological relationships among such features. This hierarchical modelling
approach allows (a) statistical inference of health for observed sites and (b)
prediction of health for unobserved sites, all accompanied by formal
uncertainty statements. Thus far, the LHFI approach has been demonstrated and
validated on freshwater ecosystems. The goal of this paper is to adapt this
approach to modelling estuarine ecosystem health, particularly that of the
previously unassessed system in Richibucto in New Brunswick, Canada. Field data
correspond to biotic health metrics that constitute the AZTI marine biotic
index (AMBI) and abiotic predictors preconceived to influence biota. We also
briefly discuss related LHFI research involving additional metrics that form
the infaunal trophic index (ITI). Our paper is the first to construct a
scientifically sensible model to rigorously identify the collective explanatory
capacity of salinity, distance downstream, channel depth, and silt-clay content
--- all regarded a priori as qualitatively important abiotic drivers ---
towards site health in the Richibucto ecosystem.Comment: On 2013-05-01, a revised version of this article was accepted for
publication in PLoS One. See Journal reference and DOI belo
Set optimization - a rather short introduction
Recent developments in set optimization are surveyed and extended including
various set relations as well as fundamental constructions of a convex analysis
for set- and vector-valued functions, and duality for set optimization
problems. Extensive sections with bibliographical comments summarize the state
of the art. Applications to vector optimization and financial risk measures are
discussed along with algorithmic approaches to set optimization problems
Using a structured decision-making tool in the classroom to promote information literacy in the context of decision-making
Using Critical Integrative Argumentation to Assess Socioscientific Argumentation Across Decision-Making Contexts
Socioscientific issues (SSI) are often used to facilitate students’ engagement in multiple scientific practices such as decision-making and argumentation, both of which are goals of STEM literacy, science literacy, and integrated STEM education. Literature often emphasizes scientific argumentation over socioscientific argumentation, which involves considering social factors in addition to scientific frameworks. Analyzing students’ socioscientific arguments may reveal how students construct such arguments and evaluate pedagogical tools supporting these skills. In this study, we examined students’ socioscientific arguments regarding three SSI on pre- and post-assessments in the context of a course emphasizing SSI-based structured decision-making. We employed critical integrative argumentation (CIA) as a theoretical and analytical framework, which integrates arguments and counterarguments with stronger arguments characterized by identifying and refuting counterarguments. We hypothesized that engaging in structured decision-making, in which students integrate multidisciplinary perspectives and consider tradeoffs of various solutions based upon valued criteria, may facilitate students’ development of integrated socioscientific arguments. Findings suggest that students’ arguments vary among SSI contexts and may relate to students’ identities and perspectives regarding the SSI. We conclude that engaging in structured decision-making regarding personally relevant SSI may foster more integrated argumentation skills, which are critical to engaging in information-laden democratic societies
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