2,168 research outputs found
CIS-lunar space infrastructure lunar technologies: Executive summary
Technologies necessary for the creation of a cis-Lunar infrastructure, namely: (1) automation and robotics; (2) life support systems; (3) fluid management; (4) propulsion; and (5) rotating technologies, are explored. The technological focal point is on the development of automated and robotic systems for the implementation of a Lunar Oasis produced by Automation and Robotics (LOAR). Under direction from the NASA Office of Exploration, automation and robotics were extensively utilized as an initiating stage in the return to the Moon. A pair of autonomous rovers, modular in design and built from interchangeable and specialized components, is proposed. Utilizing a buddy system, these rovers will be able to support each other and to enhance their individual capabilities. One rover primarily explores and maps while the second rover tests the feasibility of various materials-processing techniques. The automated missions emphasize availability and potential uses of Lunar resources, and the deployment and operations of the LOAR program. An experimental bio-volume is put into place as the precursor to a Lunar environmentally controlled life support system. The bio-volume will determine the reproduction, growth and production characteristics of various life forms housed on the Lunar surface. Physicochemical regenerative technologies and stored resources will be used to buffer biological disturbances of the bio-volume environment. The in situ Lunar resources will be both tested and used within this bio-volume. Second phase development on the Lunar surface calls for manned operations. Repairs and re-configuration of the initial framework will ensue. An autonomously-initiated manned Lunar oasis can become an essential component of the United States space program
On two intrinsic length scales in polymer physics: topological constraints vs. entanglement length
The interplay of topological constraints, excluded volume interactions,
persistence length and dynamical entanglement length in solutions and melts of
linear chains and ring polymers is investigated by means of kinetic Monte Carlo
simulations of a three dimensional lattice model. In unknotted and
unconcatenated rings, topological constraints manifest themselves in the static
properties above a typical length scale ( being
the volume fraction, the mean bond length).
Although one might expect that the same topological length will play a role
in the dynamics of entangled polymers, we show that this is not the case.
Instead, a different intrinsic length de, which scales like excluded volume
blob size , governs the scaling of the dynamical properties of both linear
chains and rings.Comment: 7 pages. 4 figure
Non-Markovian dynamics in pulsed and continuous wave atom lasers
The dynamics of atom lasers with a continuous output coupler based on two-photon Raman transitions is investigated. With the help of the time-convolutionless projection operator technique the quantum master equations for pulsed and continuous wave (cw) atom lasers are derived. In the case of the pulsed atom laser the power of the time-convolutionless projection operator technique is demonstrated through comparison with the exact solution. It is shown that in an intermediate coupling regime where the Born-Markov approximation fails the results of this algorithm agree with the exact solution. To study the dynamics of a continuous wave atom laser a pump mechanism is included in the model. Whereas the pump mechanism is treated within the Born-Markov approximation, the output coupling leads to non-Markovian effects. The solution of the master equation resulting from the time-convolutionless projection operator technique exhibits strong oscillations in the occupation number of the Bose-Einstein condensate. These oscillations are traced back to a quantum interference which is due to the non-Markovian dynamics and which decays slowly in time as a result of the dispersion relation for massive particles
Coarse Graining of Nonbonded Inter-particle Potentials Using Automatic Simplex Optimization to Fit Structural Properties
We implemented a coarse-graining procedure to construct mesoscopic models of
complex molecules. The final aim is to obtain better results on properties
depending on slow modes of the molecules. Therefore the number of particles
considered in molecular dynamics simulations is reduced while conserving as
many properties of the original substance as possible. We address the problem
of finding nonbonded interaction parameters which reproduce structural
properties from experiment or atomistic simulations. The approach consists of
optimizing automatically nonbonded parameters using the simplex algorithm to
fit structural properties like the radial distribution function as target
functions. Moreover, any mix of structural and thermodynamic properties can be
included in the target function. Different spherically symmetric inter-particle
potentials are discussed. Besides demonstrating the method for Lennard--Jones
liquids, it is applied to several more complex molecular liquids such as
diphenyl carbonate, tetrahydrofurane, and monomers of poly(isoprene).Comment: 24 pages, 3 tables, 14 figures submitted to the Journal of Chemical
Physics (JCP
DEVELOPMENT OF A TL-3 F-SHAPE TEMPORARY CONCRETE MEDIAN BARRIER
A temporary concrete median barrier (CMB) was designed and tested for compliance under the Test Level 3 (TL-3) guidelines specified in the Recommended Procedures for the Safety Performance Evaluation of Highway Features, National Cooperative Highway Research Program (NCHRP) Report No. 350. The barrier is built to the new metric standards and has a traditional pin and loop configuration for interconnection. The objective of this research project was to develop and evaluate a standardized, temporary concrete barrier design while addressing the concerns for safety, economy, structural integrity, constructability, ease of installation, and maintenance. The resulting F-shape barrier segment is 3,800-mm long, a length that reduced the number of connections while limiting the weight of the barriers to ease handling. Full-scale crash testing demonstrated several critical design features. First, the connections need to be tight initially as practicable to limit deformation and rotation of the barriers,. Secondly, the pin needs to restrain the longitudinal barrier forces. Full-scale compliance testing of the final design demonstrated that the barrier was capable of successfully redirecting the 2000-kg vehicle. The vehicle demonstrated significant roll after contact with the barrier, which is evidenced in a majority of other concrete barrier tests. This barrier provides economical work zone protection applicable in a variety of situations, where TL-3 test criteria is warranted
Pair distribution function and structure factor of spherical particles
The availability of neutron spallation-source instruments that provide total
scattering powder diffraction has led to an increased application of real-space
structure analysis using the pair distribution function. Currently, the
analytical treatment of finite size effects within pair distribution refinement
procedures is limited. To that end, an envelope function is derived which
transforms the pair distribution function of an infinite solid into that of a
spherical particle with the same crystal structure. Distributions of particle
sizes are then considered, and the associated envelope function is used to
predict the particle size distribution of an experimental sample of gold
nanoparticles from its pair distribution function alone. Finally, complementing
the wealth of existing diffraction analysis, the peak broadening for the
structure factor of spherical particles, expressed as a convolution derived
from the envelope functions, is calculated exactly for all particle size
distributions considered, and peak maxima, offsets, and asymmetries are
discussed.Comment: 7 pages, 6 figure
Exploring Spirituality in Teaching Within a Christian School Context Through Collaborative Action Research
This article reports on a collaborative action research project conducted in New Zealand, during 2012, exploring spirituality in teaching within a Christian school context. The experienced primary school teacher participant chose to take action around the issue of personal fear and insecurity which were believed to be hindering professional growth and relationships. Through self-directed inquiry, critical reflective journaling, Bible study, fellowship and prayer with trusted friends, the teacher experienced a renewed sense of peace and freedom in Christ. This personal transformation was believed to be influential on subsequent professional practice, assisting the teacher to become more relational, responsive and compassionate. The findings provide a rich description of the participant’s spirituality, the lived reality of a person’s spiritual life. This report will be of interest to teachers, teacher-leaders and teacher-educators who desire to explore Christian spirituality through practitioner-led inquiry
A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis
During late gestation, villi extend into the intestinal lumen to dramatically increase the surface area of the intestinal epithelium, preparing the gut for the neonatal diet. Incomplete development of the intestine is the most common gastrointestinal complication in neonates, but the causes are unclear. We provide evidence in mice that Yin Yang 1 (Yy1) is crucial for intestinal villus development. YY1 loss in the developing endoderm had no apparent consequences until late gestation, after which the intestine differentiated poorly and exhibited severely stunted villi. Transcriptome analysis revealed that YY1 is required for mitochondrial gene expression, and ultrastructural analysis confirmed compromised mitochondrial integrity in the mutant intestine. We found increased oxidative phosphorylation gene expression at the onset of villus elongation, suggesting that aerobic respiration might function as a regulator of villus growth. Mitochondrial inhibitors blocked villus growth in a fashion similar to Yy1 loss, thus further linking oxidative phosphorylation with late-gestation intestinal development. Interestingly, we find that necrotizing enterocolitis patients also exhibit decreased expression of oxidative phosphorylation genes. Our study highlights the still unappreciated role of metabolic regulation during organogenesis, and suggests that it might contribute to neonatal gastrointestinal disorders
Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs
In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by acting on mitochondrial function, thereby heralding a life-saving path forward for patients suffering from neuroinflammatory diseases. Disorders of myelin in the nervous system damage the transmission of signals, resulting in loss of vision, motion, sensation, and other functions depending on the affected nerves, currently with no effective treatment. Klotho genes and their single-pass transmembrane Klotho proteins are powerful governors of the threads of life and death, true to the origin of their name, Fates, in Greek mythology. Among its many important functions, Klotho is an obligatory co-receptor that binds, activates, and/or potentiates critical fibroblast growth factor activity. Since the discovery of Klotho a little over two decades ago, it has become ever more apparent that when Klotho pathways go awry, oxidative stress and mitochondrial dysfunction take over, and age-related chronic disorders are likely to follow. The physiological consequences can be wide ranging, potentially wreaking havoc on the brain, eye, kidney, muscle, and more. Central nervous system disorders, neurodegenerative in nature, and especially those affecting the myelin sheath, represent worthy targets for advancing therapies that act upon Klotho pathways. Current drugs for these diseases, even therapeutics that are disease modifying rather than treating only the symptoms, leave much room for improvement. It is thus no wonder that this topic has caught the attention of biomedical researchers around the world.https://www.liebertpub.com/doi/10.1089/biores.2020.0004Published versio
On the Significance of the Weyl Curvature in a Relativistic Cosmological Model
The Weyl curvature includes the Newtonian field and an additional field, the
so-called anti-Newtonian. In this paper, we use the Bianchi and Ricci
identities to provide a set of constraints and propagations for the Weyl
fields. The temporal evolutions of propagations manifest explicit solutions of
gravitational waves. We see that models with purely Newtonian field are
inconsistent with relativistic models and obstruct sounding solutions.
Therefore, both fields are necessary for the nonlocal nature and radiative
solutions of gravitation.Comment: 15 pages, incorporating proof correction
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