1,534 research outputs found
Evaluating Research Activity:Impact Factor vs. Research Factor
The Impact Factor (IF) “has moved ... from an obscure bibliometric indicator to become the chief quantitative measure of the quality of a journal, its research papers, the researchers who wrote those papers, and even the institution they work in” ([2], p. 1). However, the use of this index for evaluating individual scientists is dubious. The present work compares the ranking of research units generated by the Research Factor (RF) index with that associated with the popular IF. The former, originally introduced in [38], reflects article and book publications and a host of other activities categorized as coordination activities (e.g., conference organization, research group coordination), dissemination activities (e.g., conference and seminar presentations, participation in research group), editorial activities (e.g., journal editor, associate editor, referee) and functional activities (e.g., Head of Department). The main conclusion is that by replacing the IF with the RF in hiring, tenure decisions and awarding of grants would greatly increase the number of topics investigated and the number and quality of long run projects.scientific research assessment, Impact Factor, bibliometric indices, feasible Research Factor
Evidence of diffusive fractal aggregation of TiO2 nanoparticles by femtosecond laser ablation at ambient conditions
The specific mechanisms which leads to the formation of fractal
nanostructures by pulsed laser deposition remain elusive despite intense
research efforts, motivated mainly by the technological interest in obtaining
tailored nanostructures with simple and scalable production methods. Here we
focus on fractal nanostructures of titanium dioxide, , a strategic
material for many applications, obtained by femtosecond laser ablation at
ambient conditions. We model the fractal formation through extensive Monte
Carlo simulations based on a set of minimal assumptions: irreversible sticking
and size independent diffusion. Our model is able to reproduce the fractal
dimensions and the area distributions of the nanostructures obtained in the
experiments for different densities of the ablated material. The comparison of
theory and experiment show that such fractal aggregates are formed after
landing of the ablated material on the substrate surface by a diffusive
mechanism. Finally we discuss the role of the thermal conductivity of the
substrate and the laser fluence on the properties of the fractal
nanostructures. Our results represent an advancement towards controlling the
production of fractal nanostructures by pulsed laser deposition.Comment: 21 page
L’ “R-Factor”: un nuovo modo di valutare la ricerca scientifica
As pointed out in Amin e Mabe (2000, p. 1), the journal impact factor (IF) “has moved in recent years from an obscure bibliometric indicator to become the chief quantitative measure of the quality of a journal, its research papers, the researchers who wrote those papers, and even the institution they work in.” However, the use of this index for evaluating individual scientists is dubious and may “skew the course of scientific research” (Monastersky, 2005, p, 1). Moreover the IF is, at most, able to measure only the quality of a very restricted range of research activities: namely, publishing journal articles. In the present work a new indicator of a researcher quality, named the Researcher Impact Factor (RF), is introduced. It is constructed as a function of the number and quality of publications (articles, books and working papers) and of the “other activities” usually associated with being a researcher (attending and/or organizing conferences, being the Editor, Associate Editor or referee for a journal, teaching or supervising at graduate level, coordinating research groups and so on). To show the characteristics of the new index, a numerical example is carried out to rank two hypothetical scientists. The main conclusion is that by replacing the IF with the RF in hiring, tenure decisions and awarding of grants would greatly increase the number of topics investigated and the number and quality of long run projects. The Excel spreadsheet used for the computations is available on demand from the authors.Impact factor, bibliometric indices, research evaluation, researcher impact factor
Ku70 Is Required for Late B Cell Development and Immunoglobulin Heavy Chain Class Switching
Immunoglobulin (Ig) heavy chain (HC) class switch recombination (CSR) is a late B cell process that involves intrachromosomal DNA rearrangement. Ku70 and Ku80 form a DNA end-binding complex required for DNA double strand break repair and V(D)J recombination. Ku70^(−/−) (K70T) mice, like recombination activating gene (RAG)-1– or RAG-2–deficient (R1T or R2T) mice, have impaired B and T cell development at an early progenitor stage, which is thought to result at least in part from defective V(D)J recombination (Gu, Y., K.J. Seidl, G.A. Rathbun, C. Zhu, J.P. Manis, N. van der Stoep, L. Davidson, H.L. Cheng, J.M. Sekiguchi, K. Frank, et al. 1997. Immunity. 7:653–665; Ouyang, H., A. Nussenzweig, A. Kurimasa, V.C. Soares, X. Li, C. Cordon-Cardo, W. Li, N. Cheong, M. Nussenzweig, G. Iliakis, et al. 1997. J. Exp. Med. 186:921–929). Therefore, to examine the potential role of Ku70 in CSR, we generated K70T mice that carry a germline Ig HC locus in which the JH region was replaced with a functionally rearranged VH(D)JH and Ig λ light chain transgene (referred to as K70T/HL mice). Previously, we have shown that B cells from R1T or R2T mice carrying these rearranged Ig genes (R1T/HL or R2T/HL mice) can undergo CSR to IgG isotypes (Lansford, R., J. Manis, E. Sonoda, K. Rajewsky, and F. Alt. 1998. Int. Immunol. 10:325–332). K70T/HL mice had significant numbers of peripheral surface IgM^+ B cells, which generated serum IgM levels similar to those of R2T/HL mice. However, in contrast to R2T/HL mice, K70T/HL mice had no detectable serum IgG isotypes. In vitro culture of K70T/HL B cells with agents that induce CSR in normal or R2T/HL B cells did lead to the induction of germline CH transcripts, indicating that initial signaling pathways for CSR were intact in K70T/HL cells. However, treatment with such agents did not lead to detectable CSR by K70T/HL B cells, and instead, led to cell death within 72 h. We conclude that Ku70 is required for the generation of B cells that have undergone Ig HC class switching. Potential roles for Ku70 in the CSR process are discusse
Galactic chemical evolution of heavy elements: from Barium to Europium
We follow the chemical evolution of the Galaxy for elements from Ba to Eu,
using an evolutionary model suitable to reproduce a large set of Galactic
(local and non local) and extragalactic constraints. Input stellar yields for
neutron-rich nuclei have been separated into their s-process and r-process
components. The production of s-process elements in thermally pulsing
asymptotic giant branch stars of low mass proceeds from the combined operation
of two neutron sources: the dominant reaction 13C(alpha,n)16O, which releases
neutrons in radiative conditions during the interpulse phase, and the reaction
22Ne(alpha,n)25Mg, marginally activated during thermal instabilities. The
resulting s-process distribution is strongly dependent on the stellar
metallicity. For the standard model discussed in this paper, it shows a sharp
production of the Ba-peak elements around Z = Z_sun/4. Concerning the r-process
yields, we assume that the production of r-nuclei is a primary process
occurring in stars near the lowest mass limit for Type II supernova
progenitors. The r-contribution to each nucleus is computed as the difference
between its solar abundance and its s-contribution given by the Galactic
chemical evolution model at the epoch of the solar system formation. We compare
our results with spectroscopic abundances of elements from Ba to Eu at various
metallicities (mainly from F and G stars) showing that the observed trends can
be understood in the light of the present knowledge of neutron capture
nucleosynthesis. Finally, we discuss a number of emerging features that deserve
further scrutiny.Comment: 34 pages, 13 figures. accepted by Ap
Synthetic Molecular Clouds from Supersonic MHD and Non-LTE Radiative Transfer Calculations
The dynamics of molecular clouds is characterized by supersonic random
motions in the presence of a magnetic field. We study this situation using
numerical solutions of the three-dimensional compressible magneto-hydrodynamic
(MHD) equations in a regime of highly supersonic random motions. The non-LTE
radiative transfer calculations are performed through the complex density and
velocity fields obtained as solutions of the MHD equations, and more than
5x10^5 synthetic molecular spectra are obtained. We use a numerical flow
without gravity or external forcing. The flow is super-Alfvenic and corresponds
to model A of Padoan and Nordlund (1997). Synthetic data consist of sets of
90x90 synthetic spectra with 60 velocity channels, in five molecular
transitions: J=1-0 and J=2-1 for 12CO and 13CO, and J=1-0 for CS. Though we do
not consider the effects of stellar radiation, gravity, or mechanical energy
input from discrete sources, our models do contain the basic physics of
magneto-fluid dynamics and non-LTE radiation transfer and are therefore more
realistic than previous calculations. As a result, these synthetic maps and
spectra bear a remarkable resemblance to the corresponding observations of real
clouds.Comment: 33 pages, 12 figures included, 5 jpeg figures not included (fig1a,
fig1b, fig3, fig4 fig5), submitted to Ap
Evolution of Li, Be and B in the Galaxy
In this paper we study the production of Li, Be and B nuclei by Galactic
cosmic ray spallation processes. We include three kinds of processes: (i)
spallation by light cosmic rays impinging on interstellar CNO nuclei (direct
processes); (ii) spallation by CNO cosmic ray nuclei impinging on interstellar
p and 4He (inverse processes); and (iii) alpha-alpha fusion reactions. The
latter dominate the production of 6Li and 7Li. We calculate production rates
for a closed-box Galactic model, verifying the quadratic dependence of the Be
and B abundances for low values of Z. These are quite general results and are
known to disagree with observations. We then show that the multi-zone
multi-population model we used previously for other aspects of Galactic
evolution produces quite good agreement with the linear trend observed at low
metallicities without fine tuning. We argue that reported discrepancies between
theory and observations do not represent a nucleosynthetic problem, but instead
are the consequences of inaccurate treatments of Galactic evolution.Comment: 26 pages, 5 figures, LaTeX. The Astrophysical Journal, in pres
Testing the Relation Between the Local and Cosmic Star Formation Histories
Recently, there has been great progress toward observationally determining
the mean star formation history of the universe. When accurately known, the
cosmic star formation rate could provide much information about Galactic
evolution, if the Milky Way's star formation rate is representative of the
average cosmic star formation history. A simple hypothesis is that our local
star formation rate is proportional to the cosmic mean. In addition, to specify
a star formation history, one must also adopt an initial mass function (IMF);
typically it is assumed that the IMF is a smooth function which is constant in
time. We show how to test directly the compatibility of all these assumptions,
by making use of the local (solar neighborhood) star formation record encoded
in the present-day stellar mass function. Present data suggests that at least
one of the following is false: (1) the local IMF is constant in time; (2) the
local IMF is a smooth (unimodal) function; and/or (3) star formation in the
Galactic disk was representative of the cosmic mean. We briefly discuss how to
determine which of these assumptions fail, and improvements in observations
which will sharpen this test.Comment: 14 pages in LaTeX (uses aaspp4.sty). 5 postscript figures. To appear
in the Astrophysical Journa
Thermo-mechanical behavior of surface acoustic waves in ordered arrays of nanodisks studied by near infrared pump-probe diffraction experiments
The ultrafast thermal and mechanical dynamics of a two-dimensional lattice of
metallic nano-disks has been studied by near infrared pump-probe diffraction
measurements, over a temporal range spanning from 100 fs to several
nanoseconds. The experiments demonstrate that, in these systems, a
two-dimensional surface acoustic wave (2DSAW), with a wavevector given by the
reciprocal periodicity of the array, can be excited by ~120 fs Ti:sapphire
laser pulses. In order to clarify the interaction between the nanodisks and the
substrate, numerical calculations of the elastic eigenmodes and simulations of
the thermodynamics of the system are developed through finite-element analysis.
At this light, we unambiguously show that the observed 2DSAW velocity shift
originates from the mechanical interaction between the 2DSAWs and the
nano-disks, while the correlated 2DSAW damping is due to the energy radiation
into the substrate.Comment: 13 pages, 10 figure
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Infrared, UV/VIS and Raman Spectroscopy of Comet Wild-2 Samples Returned by the Stardust Mission
Results from the preliminary examination of Stardust samples obtained using various spectroscopic methods will be presented
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