Solar warming of near-bottom water over a fringing reef

The Kilo Nalu Observatory is located on the foreslope of a fringing reef on the south shore of Oahu, Hawaii. A cabled node at 12-m depth has enabled continuous real-time temperature observations from a thermistor chain extending from 1 to 7 m above bottom. Data from a 27-month deployment in 2007–2009 reveal repeated instances of subsurface temperature inversions. The usual diurnal pattern shows increases in temperature throughout the water column after sunrise, peaking in the early afternoon. Bottom waters typically warm faster than those at mid-depth, driving an inversion in the thermal profile. The onset and evolution of the inversions are consistent with an analytical model of radiation absorption and the contribution to bottom temperature from solar warming of the seafloor. The maximum size, duration and seasonal distribution of the inversions indicate that salinity compensation is a major limiting factor. In the absence of salinity compensation, the implication is that bottom heating destabilizes the water column and convective transport results. In addition, recurring afternoon onshore bottom currents contribute to the termination of inversions. Although radiative heating may exacerbate coral heat stress, radiation-driven thermal convection and exposure to the open ocean modulate temperatures over the reef

The importance of interocean exchange south of Africa in a numerical model

A fine resolution numerical model of the Southern Ocean (the Fine Resolution Antarctic Model (FRAM)) has been used to investigate the way in which heat is supplied to the South Atlantic. The heat budget in the model is compared with other estimates and is found to be broadly realistic. The temperature structure in the Atlantic, and therefore the meridional heat transport, depend heavily on the input of heat from the Indian Ocean via the Agulhas Retroflection region. FRAM is compared with three models which do not exhibit a significant input of heat from the Indian Ocean. These models also have a lower equatorward heat transport in the South Atlantic. Horizontal resolution affects the amount of Agulhas transfer with coarser resolution leading to lower heat transport in the Atlantic, a result which has implications for ocean models used in climate simulations

Pharmacists in general practice: a qualitative interview case study of stakeholders’ experiences in a West London GP Federation

Background Increased patient demand for healthcare services coupled with a shortage of general practitioners necessitates changes in professional roles and service delivery. In 2016, NHS England began a three year pilot study of pharmacists in general practice, however, this is not an entirely new initiative. There is limited, current, evidence-based, UK research to inform the pilot so studies of pre-existing services must suffice until findings from a formal national evaluation are available. Methods The aim of this exploratory, descriptive interview study was to explore the experiences of stakeholders in eight general practices in the Ealing GP Federation, West London, where pharmacy services have been provided for several years. Forty-seven participants, including pharmacy team members (pre-registration and clinical pharmacists, independent prescribers and pharmacy technicians), general practitioners, patients, practice managers, practice nurses and receptionists took part in semi-structured, audio-recorded qualitative interviews which were transcribed verbatim, coded and analysed thematically to extract the issues raised by participants and the practicalities of providing pharmacy services in general practice. Results Findings are reported under the themes of Complementarity (incorporating roles, skills, education and workloads); Integration (incorporating relationships, trust and communication) and Practicalities (incorporating location and space, access, and costs). Participants reported the need for time to develop and understand the various roles, develop communication processes and build inter-professional trust. Once these were established, however, experiences were positive and included decreased workloads, increased patient safety, improved job satisfaction, improved patient relationships, and enhanced cost savings. Areas for improvement included patients’ awareness of services; pharmacists’ training; and regular, onsite access for practice staff to the pharmacy team. Conclusions Recommendations are made for the development of clear role definitions, identification of training needs, dedication of time for team building, production of educational materials for practice staff members and patients, and provision of on-site, full-time pharmacy services. Future work should focus on evaluation of various models of employing pharmacy teams in general practice; integration of pharmacists and pharmacy technicians into multidisciplinary general practice teams; relationships between local community pharmacy and general practice personnel and patients’ service and information needs. A formal national evaluation of the pilot scheme is overdue

Bearing witness and being bounded; the experiences of nurses in adult critical care in relation to the survivorship needs of patients and families.

Aim: To discern and understand the responses of nurses to the survivorship needs of patients and family members in adult critical care units. Background: The critical care environment is a demanding place of work which may limit nurses to immediacy of care, such as the proximity to death and the pressure of work. Design: A constructivist grounded theory approach with constant comparative analysis. Methods: As part of a wider study and following ethical approval, eleven critical care nurses working within a general adult critical care unit were interviewed with respect to their experiences in meeting the psychosocial needs of patients and family members. Through the process of constant comparative analysis, an overarching selective code was constructed. EQUATOR guidelines for qualitative research (COREQ) were applied. Results: The data illuminated a path of developing expertise permitting integration of physical, psychological and family care with technology and humanity. Gaining such proficiency is demanding, and the data presented reveal the challenges that nurses experience along the way. Conclusion: The study confirms that working within a critical care environment is an emotionally charged challenge and may incur an emotional cost. Nurses can find themselves bounded by the walls of the critical care unit and experience personal and professional conflicts in their role. Nurses bear witness to the early stages of the survivorship trajectory but are limited in their support of ongoing needs. Relevance to Clinical Practice: Critical care nurses can experience personal and professional conflicts when caring for both patients and families. This can lead to moral distress and may contribute to compassion fatigue. Critical care nurses appear bounded to the delivery of physiological and technical care, in the moment, as demanded by the patient's acuity. Consequentially, this limits nurses' ability to support the onward survivorship trajectory. Increased pressure and demands on critical care beds have contributed further to occupational stress in this care setting.</p

Climate‐related variations in mixing dynamics in an Alaskan arctic lake

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109805/1/lno2009546part22401.pd

Parenting Styles Are Associated With Overall Child Dietary Quality Within Low-Income and Food-Insecure Households

Objective: To examine the association between parenting styles and overall child dietary quality within households that are low-income and food-insecure. Design: Child dietary intake was measured via a 24 h dietary recall. Dietary quality was assessed using the Healthy Eating Index-2005 (HEI-2005). Parenting styles were measured and scored using the Parenting Styles and Dimensions Questionnaire. Linear regressions were used to test main and interaction associations between HEI-2005 scores and parenting styles. Setting: Non-probability sample of low-income and food-insecure households in South Carolina, USA. Participants: Parent–child dyads (n 171). Parents were ≥18 years old and children were 9–15 years old. Results: We found a significant interaction between authoritative and authoritarian parenting style scores. For those with a mean authoritarian score, each unit increase in authoritative score was associated with a higher HEI-2005 score (b = 3·36, P \u3c 0.05). For those with an authoritarian score that was 1 SD above the mean authoritarian score, each unit increase in authoritative score was associated with a higher HEI-2005 score (b = 8.42, P \u3c 0.01). For those with an authoritarian score that was −1 SD below the mean authoritarian score, each unit increase in authoritative score was associated with a lower HEI-2005 score; however, this was not significant (b = −1·69, P \u3e 0·05). Permissive parenting style scores were negatively associated with child dietary quality (b = −2·79, P \u3c 0·05). Conclusions: Parenting styles should be considered an important variable that is associated with overall dietary quality in children living within low-income and food-insecure households

Miniature thermistor chain for determining surficial sediment porewater advection

A miniature thermistor chain (mTc) was developed to measure the subdiurnal variability of temperature in the upper layers of subtidal coastal permeable (sandy) sediments and across the sediment-water interface (SWI). The mTc has 15 precision thermistors (0.002°C accuracy) attached by narrow tines to a stainless steel backbone that connects to an electronics module, all of which is buried in the top 20 cm of the sediment. Instrument performance was tested by deploying the mTc in nearshore permeable sediment at the Kilo Nalu Observatory, Oahu, Hawaii over an 80-d period. The mTc reached thermal equilibrium with the adjoining sediment within a few days after deployment and then recorded the advective propagation of the sub-daily water-column temperature variation into the sediment. The data produced are consistent with predicted effects of surface waves on advective porewater transport: transport rate increased with wave height and decreased with depth below the SWI, and temperature time lag increased with depth below the SWI. Data from an independent, more deeply buried thermistor are in good agreement with the mTc time-series data, showing attenuated temperature variability and similar (but longer, as expected) thermal time lags. Because thermal variations in surficial sediments is dominated by advection in wavy environments, mTc subdiurnal temperature propagation data can be used to calculate advective transport across the SWI and as deep as 20 cm into the sediment (i.e., over depths where advection dominates over thermal diffusion).This is the publisher’s final pdf. The published article is copyrighted by the American Society of Limnology and Oceanography, Inc. and can be found at: http://aslo.org/lomethods/index.html

Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2

Influenza A virus’s (IAV’s) frequent genetic changes challenge vaccine strategies and engender resistance to current drugs. We sought to identify conserved and essential RNA secondary structures within IAV’s genome that are predicted to have greater constraints on mutation in response to therapeutic targeting. We identified and genetically validated an RNA structure (packaging stem–loop 2 (PSL2)) that mediates in vitro packaging and in vivo disease and is conserved across all known IAV isolates. A PSL2-targeting locked nucleic acid (LNA), administered 3 d after, or 14 d before, a lethal IAV inoculum provided 100% survival in mice, led to the development of strong immunity to rechallenge with a tenfold lethal inoculum, evaded attempts to select for resistance and retained full potency against neuraminidase inhibitor-resistant virus. Use of an analogous approach to target SARS-CoV-2, prophylactic administration of LNAs specific for highly conserved RNA structures in the viral genome, protected hamsters from efficient transmission of the SARS-CoV-2 USA_WA1/2020 variant. These findings highlight the potential applicability of this approach to any virus of interest via a process we term ‘programmable antivirals’, with implications for antiviral prophylaxis and post-exposure therapy

Theorising variation in engagement in professional and curriculum development: performativity, capital, systems and purpose

Increasingly, policymakers seek to improve the quality of teaching through curriculum innovations and continuing professional development (CPD) programmes. However, engagement by schools and teachers varies due to mediating influences of neoliberal policies. In this article, we contribute to understanding how these tendencies affect participation. Problematising the notion of context, we examine ways in which systemic influences interacted with participation in a government-funded mathematics professional and curriculum development programme and also with participants’ purposes. A 3-level clustered Randomised Controlled Trial (RCT) and an implementation and process evaluation were augmented by in-depth case studies, cross-case analysis and the application of theoretical constructs to interpret findings. Theories of capital, figured worlds and systemic coupling are utilised to theorise context. Different levels of engagement are partly explainable by: the interaction of schools' relative systemic advantage and disadvantage; their orientation and coupling to performativity regimes; and the alignment or dissonance between continuing professional development or change programmes and the pedagogical and CPD cultures and purposes of the ‘actors’ (schools, departments and teachers). Performativity concerns restricted what were considered legitimate outcomes in some case study schools. This depended on teachers and schools' positioning in terms of relative degrees of systemic privilege or disadvantage - understood as economic, cultural, social and symbolic capital - and also in terms of figured worlds and system coupling. The case studies provide insights into how collaborative professional learning can be fostered more productively. Methodologically, we demonstrate the power of combining methodologies and applying explanatory social theory to augment quasi-experimental paradigms