Matched filter for multi-transducers resonant GW antennas

We analyze two kinds of matched filters for data output of a spherical resonant GW detector. In order to filter the data of a real sphere, a strategy is proposed, firstly using an omnidirectional in-line filter, which is supposed to select periodograms with excitations, secondly by performing a directional filter on such selected periodograms, finding the wave arrival time, direction and polarization. We point out that, as the analytical simplifications occurring in the ideal 6 transducers TIGA sphere do not hold for a real sphere, using a 5 transducers configuration could be a more convenient choice.Comment: 15 pages and 4 figures, version accepted for publication in PR

Electronic contribution to the oscillations of a gravitational antenna

We carefully analyse the contribution to the oscillations of a metallic gravitational antenna due to the interaction between the electrons of the bar and the incoming gravitational wave. To this end, we first derive the total microscopic Hamiltonian of the wave-antenna system and then compute the contribution to the attenuation factor due to the electron-graviton interaction. As compared to the ordinary damping factor, which is due to the electron viscosity, this term turns out to be totally negligible. This result confirms that the only relevant mechanism for the interaction of a gravitational wave with a metallic antenna is its direct coupling with the bar normal modes.Comment: 25 pages, no figure

Amphibia, Anura, Hylidae, <i>Dendropsophus ruschii</i> (Weygoldt & Peixoto, 1987): Rediscovery of Ruschi’s treefrog in an Atlantic Rainforest remnant in Espírito Santo, Brazil

Non

A novel mutation in SACS gene in a family from southern Italy

A form of autosomal recessive spastic ataxia (ARSACS) has been described in the Charlevoix and Saguenay regions of Quebec. So far a frameshift and a nonsense mutation have been identified in the SACS gene. The authors report a new mutation (1859insC), leading to a frameshift with a premature termination of the gene product sacsin, in two sisters from consanguineous parents. The phenotype is similar to previously described patients with ARSACS

Mechanical Systems: Symmetry and Reduction

Reduction theory is concerned with mechanical systems with symmetries. It constructs a lower dimensional reduced space in which associated conservation laws are taken out and symmetries are \factored out" and studies the relation between the dynamics of the given system with the dynamics on the reduced space. This subject is important in many areas, such as stability of relative equilibria, geometric phases and integrable systems

Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis.

Barretts esophagus (BE) involves a metaplastic replacement of native esophageal squamous epithelium (Sq) by columnar-intestinalized mucosa, and it is the main risk factor for Barrett-related adenocarcinoma (BAc). Ultra-conserved regions (UCRs) are a class non-coding sequences that are conserved in humans, mice and rats. More than 90% of UCRs are transcribed (T-UCRs) in normal tissues, and are altered at transcriptional level in tumorigenesis. To identify the T-UCR profiles that are dysregulated in Barretts mucosa transformation, microarray analysis was performed on a discovery set of 51 macro-dissected samples obtained from 14 long-segment BE patients. Results were validated in an independent series of esophageal biopsy/surgery specimens and in two murine models of Barretts esophagus (i.e. esophagogastric-duodenal anastomosis). Progression from normal to BE to adenocarcinoma was each associated with specific and mutually exclusive T-UCR signatures that included up-regulation of uc.58-, uc.202-, uc.207-, and uc.223- and down-regulation of uc.214+. A 9 T-UCR signature characterized BE versus Sq (with the down-regulation of uc.161-, uc.165-, and uc.327-, and the up-regulation of uc.153-, uc.158-, uc.206-, uc.274-, uc.472-, and uc.473-). Analogous BE-specific T-UCR profiles were shared by human and murine lesions. This study is the first demonstration of a role for T-UCRs in the transformation of Barretts mucosa