34 research outputs found
Distributed Formal Concept Analysis Algorithms Based on an Iterative MapReduce Framework
While many existing formal concept analysis algorithms are efficient, they
are typically unsuitable for distributed implementation. Taking the MapReduce
(MR) framework as our inspiration we introduce a distributed approach for
performing formal concept mining. Our method has its novelty in that we use a
light-weight MapReduce runtime called Twister which is better suited to
iterative algorithms than recent distributed approaches. First, we describe the
theoretical foundations underpinning our distributed formal concept analysis
approach. Second, we provide a representative exemplar of how a classic
centralized algorithm can be implemented in a distributed fashion using our
methodology: we modify Ganter's classic algorithm by introducing a family of
MR* algorithms, namely MRGanter and MRGanter+ where the prefix denotes the
algorithm's lineage. To evaluate the factors that impact distributed algorithm
performance, we compare our MR* algorithms with the state-of-the-art.
Experiments conducted on real datasets demonstrate that MRGanter+ is efficient,
scalable and an appealing algorithm for distributed problems.Comment: 17 pages, ICFCA 201, Formal Concept Analysis 201
Isolated patellofemoral osteoarthritis: A systematic review of treatment options using the GRADE approach
Background and purpose The optimal treatment for isolated patellofemoral osteoarthritis is unclear at present. We systematically reviewed the highest level of available evidence on the nonoperative and operative treatment of isolated patellofemoral osteoarthritis to develop an evidenced-based discussion of treatment options
P.2.a.009 Prediction of response to serotonin reuptake inhibitors in patients with depression: QEEG cordance value as a predictor
AS06-02 - Can we use changes in prefrontal function to predict antidepressant response in bipolar disorder?
QEEG cordance in the prediction of response to ketamine in depressive patients - interim analysis of randomized controlled trial
ObjectiveRapid and robust antidepressant-like effect of ketamine in subanesthetic doses was already manifested in depressive patients. Maximum of mood improvement was shown within the period from 2 hours to 3 days. Previous studies proved predictive value of prefrontal QEEG theta cordance reduction after 1 week on a new antidepressant.Congruently with previous findings we hypothesised in our compressed model decrease of QEEG cordance in 10 minutes of ketamine hydrochloride infusion as the prediction of antidepressant response.Methods14 MDD patients (6F/8M) diagnosed with a moderate to severe depressive episode without psychotic symptoms were included. All of the participants received the 30 minutes lasting only infusion with subanesthetic dose of ketamine hydrochloride solution (0.54 mg/kg). EEG measurements on the baseline, after 10 and 30 minutes of infusion were taken into account in computation of QEEG cordance.Results9 (64.3%) of subjects responded to single ketamine infusion following day and 8 (88.9%) of them decreased QEEG cordance. T-test pair comparison found significant difference between baseline and after 10 minutes of ketamine infusion in responders (F = 4.12; p < 0.003).
ConclusionsPreliminary results have shown the tendency of prefrontal QEEG cordance to decrease as a ketamine response prediction. Larger sample size is needed to increased precision in estimates of cordance sensitivity and specificity. Combination of latest QEEG method and fastest-acting antidepressant-like effect of ketamine in this trail is unexampled. Supported by IGA (MH CR) No.NS10379-3, 1M0517 (MEYS CR), MZ0PCP2005 (MH CR). Local Ethics Committee approval has been granted.</jats:sec
