Treating Homeless Opioid Dependent Patients with Buprenorphine in an Office-Based Setting

CONTEXT Although office-based opioid treatment with buprenorphine (OBOT-B) has been successfully implemented in primary care settings in the US, its use has not been reported in homeless patients. OBJECTIVE To characterize the feasibility of OBOT-B in homeless relative to housed patients. DESIGN A retrospective record review examining treatment failure, drug use, utilization of substance abuse treatment services, and intensity of clinical support by a nurse care manager (NCM) among homeless and housed patients in an OBOT-B program between August 2003 and October 2004. Treatment failure was defined as elopement before completing medication induction, discharge after medication induction due to ongoing drug use with concurrent nonadherence with intensified treatment, or discharge due to disruptive behavior. RESULTS Of 44 homeless and 41 housed patients enrolled over 12 months, homeless patients were more likely to be older, nonwhite, unemployed, infected with HIV and hepatitis C, and report a psychiatric illness. Homeless patients had fewer social supports and more chronic substance abuse histories with a 3- to 6-fold greater number of years of drug use, number of detoxification attempts and percentage with a history of methadone maintenance treatment. The proportion of subjects with treatment failure for the homeless (21%) and housed (22%) did not differ (P=.94). At 12 months, both groups had similar proportions with illicit opioid use [Odds ratio (OR), 0.9 (95% CI, 0.5–1.7) P=.8], utilization of counseling (homeless, 46%; housed, 49%; P=.95), and participation in mutual-help groups (homeless, 25%; housed, 29%; P=.96). At 12 months, 36% of the homeless group was no longer homeless. During the first month of treatment, homeless patients required more clinical support from the NCM than housed patients. CONCLUSIONS Despite homeless opioid dependent patients' social instability, greater comorbidities, and more chronic drug use, office-based opioid treatment with buprenorphine was effectively implemented in this population comparable to outcomes in housed patients with respect to treatment failure, illicit opioid use, and utilization of substance abuse treatment

Digital Doppler extraction demonstration with the advanced receiver

A digital Doppler extraction demonstration with the Advanced Receiver 2 (ARX 2) tracking Pioneer 10 and Voyager 2 is described. The measured results are compared with those of the Block 4 receiver that was operating in parallel with the ARX 2. It is shown that the ARX 2 outperforms the Block 4 receiver in terms of Allan variance of the Doppler residuals, the amount of which depends on the scenario of interest

A note on the third family of N=2 supersymmetric KdV hierarchies

We propose a hamiltonian formulation of the $N=2$ supersymmetric KP type hierarchy recently studied by Krivonos and Sorin. We obtain a quadratic hamiltonian structure which allows for several reductions of the KP type hierarchy. In particular, the third family of $N=2$ KdV hierarchies is recovered. We also give an easy construction of Wronskian solutions of the KP and KdV type equations

The flavor symmetry in the standard model and the triality symmetry

A Dirac fermion is expressed by a 4 component spinor which is a combination of two quaternions and which can be treated as an octonion. The octonion possesses the triality symmetry, which defines symmetry of fermion spinors and bosonic vector fields. The triality symmetry relates three sets of spinors and two sets of vectors, which are transformed among themselves via transformations $G_{23}, G_{12}, G_{13}$, $G_{123}$ and $G_{132}$. If the electromagnetic (EM) interaction is sensitive to the triality symmetry, i.e. EM probe selects one triality sector, EM signals from the 5 transformed world would not be detected, and be treated as the dark matter. According to an astrophysical measurement, the ratio of the dark to ordinary matter in the universe as a whole is almost exactly 5. We expect quarks are insensitive to the triality, and triality will appear as three times larger flavor degrees of freedom in the lattice simulation.Comment: 16 pages 8 figures, To be published in International Journal of Modern Physics

Algebraic properties of Gardner's deformations for integrable systems

An algebraic definition of Gardner's deformations for completely integrable bi-Hamiltonian evolutionary systems is formulated. The proposed approach extends the class of deformable equations and yields new integrable evolutionary and hyperbolic Liouville-type systems. An exactly solvable two-component extension of the Liouville equation is found.Comment: Proc. conf. "Nonlinear Physics: Theory and Experiment IV" (Gallipoli, 2006); Theor. Math. Phys. (2007) 151:3/152:1-2, 16p. (to appear

Division Algebras and Extended N=2,4,8 SuperKdVs

The first example of an N=8 supersymmetric extension of the KdV equation is here explicitly constructed. It involves 8 bosonic and 8 fermionic fields. It corresponds to the unique N=8 solution based on a generalized hamiltonian dynamics with (generalized) Poisson brackets given by the Non-associative N=8 Superconformal Algebra. The complete list of inequivalent classes of parametric-dependent N=3 and N=4 superKdVs obtained from the ``Non-associative N=8 SCA" is also furnished. Furthermore, a fundamental domain characterizing the class of inequivalent N=4 superKdVs based on the "minimal N=4 SCA" is given.Comment: 14 pages, LaTe

Searching for New Physics in Leptonic Decays of Bottomonium

New Physics can show up in various well-known processes already studied in the Standard Model, in particular by modifying decay rates to some extent. In this work, I examine leptonic decays of $\Upsilon$ vector resonances of bottomonium below $B\bar{B}$ production, subsequent to a magnetic dipole radiative structural transition of the vector resonance yielding a pseudoscalar continuum state, searching for the existence of a light Higgs-like neutral boson that would imply a slight but experimentally measurable breaking of lepton universality.Comment: LaTeX, 12 pages, 1 EPS figur

Breit Hamiltonian and QED Effects for Spinless Particles

We describe a simplified derivation for the relativistic corrections of order $\alpha^4$ for a bound system consisting of two spinless particles. We devote special attention to pionium, the bound system of two oppositely charged pions. The leading quantum electrodynamic (QED) correction to the energy levels is of the order of $\alpha^3$ and due to electronic vacuum polarization. We analyze further corrections due to the self-energy of the pions, and due to recoil effects, and we give a complete result for the scalar-QED leading logarithmic corrections which are due to virtual loops involving only the scalar constituent particles (the pions); these corrections are of order $\alpha^5 \ln \alpha$ for S states.Comment: 12 pages, LaTeX; references added (J. Phys. B, in press

Invariant vector fields and the prolongation method for supersymmetric quantum systems

The kinematical and dynamical symmetries of equations describing the time evolution of quantum systems like the supersymmetric harmonic oscillator in one space dimension and the interaction of a non-relativistic spin one-half particle in a constant magnetic field are reviewed from the point of view of the vector field prolongation method. Generators of supersymmetries are then introduced so that we get Lie superalgebras of symmetries and supersymmetries. This approach does not require the introduction of Grassmann valued differential equations but a specific matrix realization and the concept of dynamical symmetry. The Jaynes-Cummings model and supersymmetric generalizations are then studied. We show how it is closely related to the preceding models. Lie algebras of symmetries and supersymmetries are also obtained.Comment: 37 pages, 7 table

Relativistic and Binding Energy Corrections to Direct Photon Production In Upsilon Decay

A systematic gauge-invariant method is used to calculate the rate for an upsilon meson to decay inclusively into a prompt photon. An expansion is made in the quark relative velocity v, which is a small natural parameter for heavy quark systems. Inclusion of these O(v^2) corrections tends to increase the photon rate in the middle z range and to lower it for larger z, a feature supported by the data.Comment: 13 pages, LateX, One figure (to be published in Phys. Rev. D, Sept. 1, 1996