Influence of nitrogen salts on growth and physiological responses of Rhizophora apiculata Blume in non-aerated water culture

Influence of two different forms of nitrogen on growth and physiological aspects of water-cultured seedlings of Rhizophora apiculata was studied. Of the two forms of nitrogen supplied to the growth medium, ammonium nitrogen was better than nitrate nitrogen by exhibiting increased dry matter production, shoot length, leaf area and also enhanced the contents of carotenoids, chlorophylls and their presence in photosystems and light harvesting protein complex

Account of the Flatfishes of the Mangalore Coast and Notes on their Fishery

12 specimens were studied for morphological and meristic characters. Most characters agreed with earlier descriptions. Dorsal and anal fins were tipped white unlike black as reported by Fischer and Bianchi (1984). Maximum length recorded was 540 mm

Nicotine, IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades

BACKGROUND: The membrane-bound mucins are thought to play an important biological role in cell–cell and cell–matrix interactions, in cell signaling and in modulating biological properties of cancer cell. MUC4, a transmembrane mucin is overexpressed in pancreatic tumors, while remaining undetectable in the normal pancreas, thus indicating a potential role in pancreatic cancer pathogenesis. The molecular mechanisms involved in the regulation of MUC4 gene are not yet fully understood. Smoking is strongly correlated with pancreatic cancer and in the present study; we elucidate the molecular mechanisms by which nicotine as well as agents like retinoic acid (RA) and interferon-γ (IFN-γ) induce the expression of MUC4 in pancreatic cancer cell lines CD18, CAPAN2, AsPC1 and BxPC3. RESULTS: Chromatin immunoprecipitation assays and real-time PCR showed that transcription factors E2F1 and STAT1 can positively regulate MUC4 expression at the transcriptional level. IFN-γ and RA could collaborate with nicotine in elevating the expression of MUC4, utilizing E2F1 and STAT1 transcription factors. Depletion of STAT1 or E2F1 abrogated the induction of MUC4; nicotine-mediated induction of MUC4 appeared to require α7-nicotinic acetylcholine receptor subunit. Further, Src and ERK family kinases also mediated the induction of MUC4, since inhibiting these signaling molecules prevented the induction of MUC4. MUC4 was also found to be necessary for the nicotine-mediated invasion of pancreatic cancer cells, suggesting that induction of MUC4 by nicotine and other agents might contribute to the genesis and progression of pancreatic cancer. CONCLUSIONS: Our studies show that agents that can promote the growth and invasion of pancreatic cancer cells induce the MUC4 gene through multiple pathways and this induction requires the transcriptional activity of E2F1 and STAT1. Further, the Src as well as ERK signaling pathways appear to be involved in the induction of this gene. It appears that targeting these signaling pathways might inhibit the expression of MUC4 and prevent the proliferation and invasion of pancreatic cancer cells

Heterogeneity in pre-monsoon aerosol types over the Arabian Sea deduced from ship-borne measurements of spectral AODs

Ship-borne sunphotometer measurements obtained in the Arabian Sea (AS) in the pre-monsoon season (18 April–10 May 2006) during a cruise campaign (ICARB) have been used to retrieve the Aerosol Optical Depth (AOD; τ) and the Ångström wavelength exponent (α). The continents surrounding the AS produce natural and anthropogenic aerosols that have distinctive influences on α and its spectral distribution. The α values were estimated by means of the least-squares method over the spectral bands 340–1020 nm and 340–870 nm. The spectral distribution of AOD in logarithmic co-ordinates could be fit using a 2nd order polynomial with higher accuracy in the wavelength band 340–1020 nm than in the 340–870 nm band. A polynomial fit analytically parameterizes the observed wavelength dependencies of AOD with least errors in spectral variation of α and yields accurate estimates of the coefficients (<i>a</i><sub>1</sub> and <i>a</i><sub>2</sub>). The coarse-mode (positive curvature in the lnτ<sub>λ</sub> vs. lnλ) aerosols are mainly depicted in the Northern part of the AS closely associated with the nearby arid areas while fine-mode aerosols are mainly observed over the far and coastal AS regions. In the study period the mean AOD at 500 nm is 0.25±0.11 and the α<sub>340-1020</sub> is 0.90±0.19. The α<sub>340-870</sub> exhibits similar values (0.92±0.18), while significant differences revealed for the constant terms of the polynomial fit (<i>a</i><sub>1</sub> and <i>a</i><sub>2</sub>) proportionally to the wavelength band used for their determination. Observed day-to-day variability in the aerosol load and optical properties are direct consequence of the local winds and air-mass trajectories along with the position of the ship

Stellar Population Gradients in Bulges along the Hubble Sequence: I. The Data

This is the first paper presenting our long-term project aimed at studying the nature of bulges through the analysis of their stellar population gradients. We present deep spectroscopic observations along the minor axis and the data reduction for a sample of 32 bulges of edge-on spiral galaxies. We explain in detail our procedures to measure their dynamical parameters (rotation curves and velocity dispersion profiles) and line-strength indices, including the conversion to the Lick/IDS system. Tables giving the values of the dynamical parameters and line-strength indices at each galactocentric radius are presented (in electronic form) for each galaxy of the sample. The derived line-strength gradients from this dataset will be analyzed in a forthcoming paper to set constraints on the different scenarios for the formation of the bulges.Comment: Accepted for publication in A&

CRYSTAL GROWTH AND NON-LINEAR APPLICATION OF SULPHA DRUG-AN INVITRO ANTIBACTERIAL EFFECT AGAINST ESBL (EXTRENDED SPECTRUM OF BETA LACTAMSE)

 A probe into the literature survey clearly reveals no work has been carried out for the synthesis of 4-(Phenyl sulfonyl) morpholine and 4-(Phenyl sulfony) morpholine potassium hydrogen phosphate using TLC 4-(Phenyl sulfonyl)morpholine and 4-(Phenyl sulfony) morpholine potassium hydrogen phosphate. Aim and scope of the work is highly effective medicinal hydrazide derivatives have been synthesized from Schiff base route. The structure of the ligand THC and its complexes were carried various spectral studies. From these studies, I know about the knowledge of organic chemistry and spectroscopy. In my present work, we have to synthesis of and 4-(Phenyl sulfonyl) morpholine and 4- (Phenyl sulfony) morpholine potassium hydrogen phosphate establish the structure through the analytical (elemental and TLC) and spectral (IR, H1 NMR) methods of characterization.&nbsp

COPPER –CATALYZED ELECTROPHILIC AMINATION OF ARYLSILANES WITH HYDROXYLAMINES

A copper-catalyzed electrophilic amination of aryl((2-hydroxymethyl)phenyl)dimethylsilanes with O-acylated hydroxylamines has been createdto manage the cost of the relating anilines in great yields. The synergist response continues easily under gentle conditions and endures a wide scope of utilitarian gatherings

A Fingerprint Identification Approach using Neural Networks

Today, because of the vulnerability of standard authentication system, law-breaking has accumulated within the past few years. Identity authentication that relies on biometric feature like face, iris, voice, hand pure mathematics, handwriting, retina, fingerprints will considerably decrease the fraud, so that they square measure being replaced by identity verification mechanisms. Among bioscience, fingerprint systems are one amongst most generally researched and used. it\'s fashionable due to their easy accessibility. Moreover in this work the system modified to an adaptive system i.e intelligent by using neural networks

A177: Program Evaluation of the ACR/CARRA Inter‐Institutional Mentoring Program (AMIGO) in Pediatric Rheumatology

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106776/1/art38603.pd