2,374 research outputs found

    Dynamical generation of interwoven soliton trains by nonlinear emission in binary Bose-Einstein condensates

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    We propose a method for the generation of trains of alternating bright solitons in two-component Bose-Einstein condensates, using controlled emission of nonlinear matter-waves in the uncoupled regime with spatially-varying intra-species interaction and out-of-phase oscillations of the ground states in the trap. Under this scheme, solitons are sequentially launched from the different components, and interact with each other through phase-independent cross-coupling. We obtain an analytical estimation of the critical condition for soliton emission using a geometric guiding model, in analogy with integrated optical systems. In addition, we show how strong initial perturbations in the system can trigger the spontaneous generation of supersolitons, i.e. localized phonon-like excitations of the soliton trains. Finally, we demonstrate the controllable generation of slow and fast supersolitons by adding external localized potentials in the nonlinear region

    Implementation of liquid culture for tuberculosis diagnosis in a remote setting: lessons learned.

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    Although sputum smear microscopy is the primary method for tuberculosis (TB) diagnosis in low-resource settings, it has low sensitivity. The World Health Organization recommends the use of liquid culture techniques for TB diagnosis and drug susceptibility testing in low- and middle-income countries. An evaluation of samples from southern Sudan found that culture was able to detect cases of active pulmonary TB and extra-pulmonary TB missed by conventional smear microscopy. However, the long delays involved in obtaining culture results meant that they were usually not clinically useful, and high rates of non-tuberculous mycobacteria isolation made interpretation of results difficult. Improvements in diagnostic capacity and rapid speciation facilities, either on-site or through a local reference laboratory, are crucial

    Polarization-Tailored Raman Frequency Conversion in Chiral Gas-Filled Hollow Core Photonic Crystal Fibers

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    Broadband-tunable sources of circularly-polarized light are crucial in fields such as laser science, biomedicine and spectroscopy. Conventional sources rely on nonlinear wavelength conversion and polarization control using standard optical components, and are limited by the availability of suitably transparent crystals and glasses. Although gas-filled hollow-core photonic crystal fiber provides pressure-tunable dispersion, long well-controlled optical path-lengths, and high Raman conversion efficiency, it is unable to preserve circular polarization state, typically exhibiting weak linear birefringence. Here we report a revolutionary approach based on helically-twisted hollow-core photonic crystal fiber, which displays circular birefringence, thus robustly maintaining circular polarization state against external perturbations. This makes it possible to generate pure circularly-polarized Stokes and anti-Stokes signals by rotational Raman scattering in hydrogen. The polarization state of the frequency-shifted Raman bands can be continuously varied by tuning the gas pressure in the vicinity of the gain suppression point. The results pave the way to a new generation of compact and efficient fiber-based sources of broadband light with fully-controllable polarization state.Comment: 5 pages, 4 figure

    Novel mid-infrared dispersive wave generation in gas-filled PCF by transient ionization-driven changes in dispersion

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    Gas-filled hollow-core photonic crystal fibre (PCF) is being used to generate ever wider supercontinuum spectra, in particular via dispersive wave (DW) emission in the deep and vacuum ultraviolet, with a multitude of applications. DWs are the result of the resonant transfer of energy from a self-compressed soliton, a process which relies crucially on phase matching. It was recently predicted that, in the strong-field regime, the additional transient anomalous dispersion introduced by gas ionization would allow phase-matched DW generation in the mid-infrared (MIR)-something that is forbidden in the absence of free electrons. Here we report for the first time the experimental observation of such MIR DWs, embedded in a 4.7-octave-wide supercontinuum that uniquely reaches simultaneously to the vacuum ultraviolet, with up to 1.7 W of total average power

    Artritis séptica por streptococcus pneumoniae: reporte de un caso

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    La artritis neumocócica es infrecuente en adultos, predomina en pacientes pediátricos. La neumonía y la bacteriemia son las manifestaciones más frecuentes, la afectación articular según series recientes tiene una prevalencia menor al 1% en sujetos menores de 50 años. Se presenta el caso de una paciente de 60 años con LES (Lupus Eritematoso Sistémico) la cual presentó monoartritis séptica de rodilla derecha causada por Streptococcus pneumoniaePneumococcal arthritis is uncommon in adults, predominantly in pediatric patients. Pneumonia and bacteremia are the most common manifestations; joint involvement according to recent series has a lower prevalence of 1% in subjects under 50 years. We report the case of a patient of 60 years with SLE (systemic lupus erythematosus) which presented septic monoarthritis right knee caused by Streptococcus pneumoniae

    The effects of Reiki treatment on mental health professionals who are at risk for secondary traumatic stress

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    The purpose of this cross-sectional experimental study was to examine the effects of Reiki on risk level for secondary traumatic stress (STS) among mental health professionals, such as, social workers and licensed professional counselor (LPCs). The sample (N=67) was mostly composed of master social work students (MSW) (61%) from the School of Social Work at Louisiana State University (LSU), professionals social workers (34%), and LPCs (5%). Study participants were randomly assigned to one of three treatment groups: Reiki, placebo or control group. Dependent variables measured at pretest and posttest were: risk level for STS, anxiety, depression, somatic symptoms, anger and hopelessness. Multivariate analysis of variance was conducted to determine if there was a difference between treatment groups. No significant difference was found between the Reiki, placebo or control groups on any of the variables measured. Implications for the social work profession are discussed

    Electron affinities of the first- and second- row atoms: benchmark ab initio and density functional calculations

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    A benchmark ab initio and density functional (DFT) study has been carried out on the electron affinities of the first- and second-row atoms. The ab initio study involves basis sets of spdfghspdfgh and spdfghispdfghi quality, extrapolations to the 1-particle basis set limit, and a combination of the CCSD(T), CCSDT, and full CI electron correlation methods. Scalar relativistic and spin-orbit coupling effects were taken into account. On average, the best ab initio results agree to better than 0.001 eV with the most recent experimental results. Correcting for imperfections in the CCSD(T) method improves the mean absolute error by an order of magnitude, while for accurate results on the second-row atoms inclusion of relativistic corrections is essential. The latter are significantly overestimated at the SCF level; for accurate spin-orbit splitting constants of second-row atoms inclusion of (2s,2p) correlation is essential. In the DFT calculations it is found that results for the 1st-row atoms are very sensitive to the exchange functional, while those for second-row atoms are rather more sensitive to the correlation functional. While the LYP correlation functional works best for first-row atoms, its PW91 counterpart appears to be preferable for second-row atoms. Among ``pure DFT'' (nonhybrid) functionals, G96PW91 (Gill 1996 exchange combined with Perdew-Wang 1991 correlation) puts in the best overall performance. The best results overall are obtained with the 1-parameter hybrid modified Perdew-Wang (mPW1) exchange functionals of Adamo and Barone [J. Chem. Phys. {\bf 108}, 664 (1998)], with mPW1LYP yielding the best results for first-row, and mPW1PW91 for second-row atoms. Indications exist that a hybrid of the type aa mPW1LYP + (1a)(1-a) mPW1PW91 yields better results than either of the constituent functionals.Comment: Phys. Rev. A, in press (revised version, review of issues concerning DFT and electron affinities added

    A preliminary study of genetic factors that influence susceptibility to bovine tuberculosis in the British cattle herd

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    Associations between specific host genes and susceptibility to Mycobacterial infections such as tuberculosis have been reported in several species. Bovine tuberculosis (bTB) impacts greatly the UK cattle industry, yet genetic predispositions have yet to be identified. We therefore used a candidate gene approach to study 384 cattle of which 160 had reacted positively to an antigenic skin test (‘reactors’). Our approach was unusual in that it used microsatellite markers, embraced high breed diversity and focused particularly on detecting genes showing heterozygote advantage, a mode of action often overlooked in SNP-based studies. A panel of neutral markers was used to control for population substructure and using a general linear model-based approach we were also able to control for age. We found that substructure was surprisingly weak and identified two genomic regions that were strongly associated with reactor status, identified by markers INRA111 and BMS2753. In general the strength of association detected tended to vary depending on whether age was included in the model. At INRA111 a single genotype appears strongly protective with an overall odds ratio of 2.2, the effect being consistent across nine diverse breeds. Our results suggest that breeding strategies could be devised that would appreciably increase genetic resistance of cattle to bTB (strictly, reduce the frequency of incidence of reactors) with implications for the current debate concerning badger-culling
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