Etude d'un virus vaccin modifié contre la Peste porcine classique préparé à partir d'une souche « Chinoise » (CL) adaptée à la culture de cellules rénales d 'Agneau. Emploi dons les conditions de la pratique

Goret Pierre, Precausta P., Perrenot F. Étude d’un virus vaccin modifié contre la Peste porcine classique préparé à partir d’une souche “Chinoise” (CL) adaptée à la culture de cellules rénales d’Agneau. Emploi dans les conditions de la pratique. In: Bulletin de l'Académie Vétérinaire de France tome 124 n°6, 1971. pp. 257-262

Influence of residual moisture and sealing atmosphere on viability of two freeze-dried viral vaccines

This study demonstrated the complexity of the factors leading to changes in the infectivity titers of freeze-dried canine distemper and poultry infectious bronchitis viral vaccines. The change in moisture content during the storage period was an additional parameter which may influence the infectivity titer. The results emphasized the difficulty of predetermining variations in infectivity titers from the initial residual moisture. The analysis of the variations in infectivity titers during the storage of two vaccines led to the formulation of a hypothesis of the presence of two components of different thermostability. Moreover, the temporary increase in the infectivity titer of infectious bronchitis vaccine stored progressively dissociating during storage concurrent with a progressive inactivation of infectious particles.</jats:p