Faktor-faktor Yang Berhubungan Dengan Status Anemia Ibu Hamil Di Wilayah Kerja Puskesmas Air Dingin Kecamatan Koto Tangah, Kota Padang

Latar Belakang : Anemia pada kehamilan saat ini masih menjadi masalah utama yang diderita oleh hampir separuh wanita hamil di seluruh negara di dunia, termasuk Indonesia. Anemia pada kehamilan merupakan “potential danger to mother and child” (potensial membahayakan ibu dan anak). Secara umum, penyebab utama anemia kehamilan adalah kekurangan zat besi yang timbul sebagai akibat dari peningkatan penggunaan zat besi untuk janin. Tujuan : menilai faktor-faktor yang hubungan dengan status anemia pada ibu hamil di wilayah kerja Puskesmas Air Dingin, Kecamatan Kota Tangah, Kota Padang. Metode : Jenis penelitian ini Cross sectional. Alat pengumpul data yang digunakan adalah melalui pengisian kuesioner dan sampel diambil dengan cara Simple Random Sampling. Penelitian ini dilaksanakan pada bulan April– Mei tahun 2014 yang bertempat di Kecamatan Wilayah Kerja Puskesmas Air Dingin Koto Tangah Kota Padang. Pengolahan dan analisis data dilakukan dengan SPSS versi 16 data di analisa univariat dan bivariat dengan Uji Chi-Square pada tingkat kemaknaan 0,05. Hasil : Sebesar 69,4 persen ibu hamil mengalami anemia. Uji chi square menunjukkan hubungan bermakna antara umur kehamilan, suplementasi tablet besi, dan konsumsi (protein, lemak, vitamin c, dan zat besi) terhadap status anemia pada ibu hamil. Kesimpulan : Pencegahan anemia pada ibu hamil dilakukan dengan meningkatkan konsumsi zat gizi dan peningkatan pengetahuan melalui promosi kesehatan ibu hamil mengenai anemia

Proper Motion of the Faint Star near KIC 8462852 (Boyajian's Star) - Not a Binary System

A faint star located 2 arcsec from KIC 8462852 was discovered in Keck 10 m adaptive optics imaging in the $JHK$ near-infrared (NIR) in 2014 by Boyajian et al. (2016). The closeness of the star to KIC 8462852 suggested the two could constitute a binary, which might have implications for the cause of the brightness dips seen by {\it Kepler} (Boyajian et al. (2016) and in ground-based optical studies Boyajian et al. (2018). Here, NIR imaging in 2017 using the Mimir instrument resolved the pair and enabled measuring their separation. The faint star had moved $67 \pm 7$ milliarcsec (mas) relative to KIC 8462852 since 2014. The relative proper motion of the faint star is $23.9 \pm 2.6$ mas yr$^{-1}$, for a tangential velocity of $45 \pm 5$ km s$^{-1}$ if it is at the same 390 pc distance as KIC 8462852. Circular velocity at the 750 AU current projected separation is $1.5$ km s$^{-1}$, hence the star pair cannot be bound.Comment: 10 pages, 2 figure

Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice

Background: Allergic asthma is a chronic inflammatory respiratory disease associated with eosinophilic infiltration, increased mucus production, airway hyperresponsiveness (AHR), and airway remodeling. Epidemiologic data has revealed that the prevalence of allergic sensitization and associated diseases has increased in the twentieth century. This has been hypothesized to be partly due to reduced contact with microbial organisms (the hygiene hypothesis) in industrialized society. Airway epithelial cells, once considered a static physical barrier between the body and the external world, are now widely recognized as immunologically active cells that can initiate, maintain, and restrain inflammatory responses, such as those that mediate allergic disease. Airway epithelial cells can sense allergens via myriad expression of Toll-like receptors (TLRs) and other pattern-recognition receptors (PRRs). Methods: We sought to determine whether the innate immune response stimulated by a combination of Pam2CSK4 (“Pam2”, TLR2/6 ligand) and a class C oligodeoxynucleotide ODN362 (“ODN”, TLR9 ligand) when delivered together by aerosol (“Pam2ODN”), can modulate the allergic immune response to allergens. Results Treatment with Pam2ODN 7 days before sensitization to House Dust Mite (HDM) extract resulted in a strong reduction in eosinophilic and lymphocytic inflammation. This Pam2ODN immunomodulatory effect was also seen using Ovalbumin (OVA) and A. oryzae (Ao) mouse models. Conclusion The immunomodulatory effect was observed as much as 30 days before sensitization to HDM, but ineffective just 2 days after sensitization, suggesting that Pam2ODN immunomodulation lowers the allergic responsiveness of airway epithelial cells. Furthermore, Pam2 and ODN cooperated synergistically suggesting that this treatment is superior to any single agonist in the setting of allergen immunotherapy

Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice

Allergic asthma is a chronic inflammatory respiratory disease associated with eosinophilic infiltration, increased mucus production, airway hyperresponsiveness, and airway remodeling. Epidemiologic data reveal that the prevalence of allergic sensitization and associated diseases has increased in the twentieth century. This has been hypothesized to be partly due to reduced contact with microbial organisms (the hygiene hypothesis) in industrialized society. Airway epithelial cells, once considered a static physical barrier between the body and the external world, are now widely recognized as immunologically active cells that can initiate, maintain, and restrain inflammatory responses, such as those that mediate allergic disease. Airway epithelial cells can sense allergens via expression of myriad Toll-like receptors (TLRs) and other pattern-recognition receptors. We sought to determine whether the innate immune response stimulated by a combination of Pam2CSK4 (“Pam2”, TLR2/6 ligand) and a class C oligodeoxynucleotide ODN362 (“ODN”, TLR9 ligand), when delivered together by aerosol (“Pam2ODN”), can modulate the allergic immune response to allergens. Treatment with Pam2ODN 7 days before sensitization to House Dust Mite (HDM) extract resulted in a strong reduction in eosinophilic and lymphocytic inflammation. This Pam2ODN immunomodulatory effect was also seen using Ovalbumin (OVA) and A. oryzae (Ao) mouse models. The immunomodulatory effect was observed as much as 30 days before sensitization to HDM, but ineffective just 2 days after sensitization, suggesting that Pam2ODN immunomodulation lowers the allergic responsiveness of the lung, and reduces the likelihood of inappropriate sensitization to aeroallergens. Furthermore, Pam2 and ODN cooperated synergistically suggesting that this treatment is superior to any single agonist in the setting of allergen immunotherapy

Epithelial Immunomodulation by Aerosolized Toll-Like Receptor Agonists Prevents Allergic Inflammation in Airway Mucosa in Mice

Allergic asthma is a chronic inflammatory respiratory disease associated with eosinophilic infiltration, increased mucus production, airway hyperresponsiveness, and airway remodeling. Epidemiologic data reveal that the prevalence of allergic sensitization and associated diseases has increased in the twentieth century. This has been hypothesized to be partly due to reduced contact with microbial organisms (the hygiene hypothesis) in industrialized society. Airway epithelial cells, once considered a static physical barrier between the body and the external world, are now widely recognized as immunologically active cells that can initiate, maintain, and restrain inflammatory responses, such as those that mediate allergic disease. Airway epithelial cells can sense allergens via expression of myriad Toll-like receptors (TLRs) and other pattern-recognition receptors. We sought to determine whether the innate immune response stimulated by a combination of Pam2CSK4 (“Pam2”, TLR2/6 ligand) and a class C oligodeoxynucleotide ODN362 (“ODN”, TLR9 ligand), when delivered together by aerosol (“Pam2ODN”), can modulate the allergic immune response to allergens. Treatment with Pam2ODN 7 days before sensitization to House Dust Mite (HDM) extract resulted in a strong reduction in eosinophilic and lymphocytic inflammation. This Pam2ODN immunomodulatory effect was also seen using Ovalbumin (OVA) and A. oryzae (Ao) mouse models. The immunomodulatory effect was observed as much as 30 days before sensitization to HDM, but ineffective just 2 days after sensitization, suggesting that Pam2ODN immunomodulation lowers the allergic responsiveness of the lung, and reduces the likelihood of inappropriate sensitization to aeroallergens. Furthermore, Pam2 and ODN cooperated synergistically suggesting that this treatment is superior to any single agonist in the setting of allergen immunotherapy

Experimental investigation of performance and emissions characteristics of waste cooking oil biodiesel and n-butanol blends in a compression ignition engine

Experimental investigations were conducted to evaluate the effects of n-butanol in biodiesel–diesel blends on the performance and emissions characteristics of a constant speed, direct injection diesel engine.</p

Internationalization Oriented Coaching Activities Promoting Organisational Changes In Baltic Countries

The aim of this paper is to investigate the role and application of coaching as an internationalization- oriented facilitative intervention for organizational change. The paper employs qualitative methods of research: literature review, interview, content analysis, comparative analysis. The paper integrates the conceptual consideration of organizational coaching with the results gained from the interviews with the experts in coaching in the Baltic countries. The role and application of coaching are identified and the results are compared. The findings suggest that coaching is effective when it suits the development needs of an organization. Theoretical and practical implications are discussed