Mergers

Using small matched samples of companies which are, and are not, highly involved in acquisition in the period 1986-90, an investigation is mounted to ascertain whether "acquisitiveness" has any impact upon the remuneration of the top directors over and above what one would expect because of the growth in "size". The evidence suggests it does, if returns to share options are included in the measure of remuneration.

Evaporation of a packet of quantized vorticity

A recent experiment has confirmed the existence of quantized turbulence in superfluid He3-B and suggested that turbulence is inhomogenous and spreads away from the region around the vibrating wire where it is created. To interpret the experiment we study numerically the diffusion of a packet of quantized vortex lines which is initially confined inside a small region of space. We find that reconnections fragment the packet into a gas of small vortex loops which fly away. We determine the time scale of the process and find that it is in order of magnitude agreement with the experiment.Comment: figure 1a,b,c and d, figure2, figure

Preliminary assessment of abdominal organ perfusion utilizing a fiber optic photoplethysmographic sensor

In an attempt to overcome the limitations of current techniques for monitoring abdominal organ perfusion, a prototype reflectance fiber optic photoplethysmographic (PPG) sensor and processing system was evaluated on seventeen anaesthetized patients undergoing laparotomy. Good quality PPG signals were obtained from the large bowel, small bowel, liver and stomach. Simultaneous PPG signals from the finger were also obtained for comparison purposes using an identical fiber optic sensor. Analysis of the mean ac and dc PPG amplitudes of all acquired signals indicated larger amplitudes for those signals obtained from abdominal organs than those obtained from the finger. Mean estimated blood oxygen saturation (SpO2) values from all abdominal sites showed good agreement with those obtained from the finger using both the finger fiber optic sensor and a commercial finger pulse oximeter. Furthermore, a Bland and Altman between-method-differences analysis on the estimated SpO2 data suggests that a fiber optic abdominal sensor may be a suitable method for the evaluation of abdominal organ perfusion

Development and evaluation of a photometric fibre-optic sensor for monitoring abdominal organ photoplethysmographs and blood oxygen saturation

A two wavelength photometric fibre-optic reflectance sensor was developed for assessing abdominal organ perfusion. In vitro tests showed that reliable photoplethysmographic (PPG) signals and blood oxygen saturation (SpO2) values were recorded when the separation between emitting and receiving fibres was at 3mm and the emitting current was between 20mA-40mA. In a clinical study, good quality PPG signals were obtained from the small and large bowel of a patient undergoing laparotomy. Abdominal organ SpO2 were in good agreement with those obtained from a commercial device. These observations suggest that the fibre-optic sensor may be suitable for monitoring abdominal organ perfusion

In-Vivo Evaluation of a Fiber-Optic Splanchnic Photoplethysmographic Sensor during Open Laparotomy

There is a need for a reliable and continuous monitoring of abdominal organ oxygen saturation (SpO2). Splanchnic ischemia may ultimately lead to cellular hypoxia and necrosis and may well contribute to the development of multiple organ failures and increased mortality. A new prototype reflectance fiber optic photoplethysmographic sensor and signal processing system was evaluated on six anaesthetized patients undergoing elective laparotomy. PPG signals were obtained from various organs, including large and small bowel, liver, and stomach. The normalized amplitudes of the splanchnic PPG signals were in good agreement with those obtained from the periphery using an identical fiber optic sensor. Furthermore, average SpO2 values were in good agreement and showed correlation with those obtained from a commercial system. These preliminary results suggest that a miniaturized `indwelling' fiber optic sensor may be a suitable method for pre-operative and post-operative evaluation of splanchnic organ SpO2 and their health

A New Fibre Optic Pulse Oximeter Probe for Monitoring Splanchnic Organ Arterial Blood Oxygen Saturation

a new continuous method of monitoring splanchnic organ oxygen saturation (SpO2) would make the early detection of inadequate tissue oxygenation feasible, reducing the risk of hypoperfusion, severe ischaemia, and, ultimately, death. In an attempt to provide such a device, a new fiber optic based reflectance pulse oximeter probe and processing system were developed followed by an in vivo evaluation of the technology on seventeen patients undergoing elective laparotomy. Photoplethysmographic (PPG) signals of good quality were obtained from the small bowel, large bowel, liver and stomach. Simultaneous peripheral PPG signals from the finger were also obtained for comparison purposes. Analysis of the amplitudes of all acquired PPG signals indicated much larger amplitudes for those signals obtained from splanchnic organs than those obtained from the periphery. Estimated SpO2 values for splanchnic organs showed good agreement with those obtained from the peripheral fibre optic probe and those obtained from a commercial device. These preliminary results suggest that a miniaturized ‘indwelling’ fibre optic sensor may be a suitable method for pre-operative and post-operative evaluation of splanchnic organ SpO2 and their health

Regression Analysis of a Disease Onset Distribution Using Diagnosis Data

We consider methods for estimating the effect of a covariate on a disease onset distribution when the observed data structure consists of right-censored data on diagnosis times and current status data on onset times amongst individuals who have not yet been diagnosed. Dunson and Baird (2001) approached this problem using maximum likelihood, under the assumption that the ratio of the diagnosis and onset distributions is monotonic non-decreasing. As an alternative, we propose a two-step estimator, an extension of the approach of van der Laan, Jewell and Petersen (1997) in the single sample setting, that is computationally much simpler and requires no assumptions on this ratio. A simulation study is performed comparing estimates obtained from these two approaches, as well as that from a standard current status analysis that ignores diagnosis data. Results indicate that the Dunson and Baird estimator outperforms the two-step estimator when the monotonicity assumption holds, but the reverse is true when the assumption fails. The simple current status estimator loses only a small amount of precision in comparison to the two-step procedure but requires monitoring time information for all individuals. In the data that motivated this work, a study of uterine fibroids and chemical exposure to dioxin, the monotonicity assumption is seen to fail. Here, the two-step and current status estimators both show no significant association between the level of dioxin exposure and the hazard for onset of uterine fibroids; the two-step estimator of the relative hazard associated with increasing levels of exposure has the least estimated variance amongst the three estimators considered