Destruction of Interstellar Dust in Evolving Supernova Remnant Shock Waves

Supernova generated shock waves are responsible for most of the destruction of dust grains in the interstellar medium (ISM). Calculations of the dust destruction timescale have so far been carried out using plane parallel steady shocks, however that approximation breaks down when the destruction timescale becomes longer than that for the evolution of the supernova remnant (SNR) shock. In this paper we present new calculations of grain destruction in evolving, radiative SNRs. To facilitate comparison with the previous study by Jones et al. (1996), we adopt the same dust properties as in that paper. We find that the efficiencies of grain destruction are most divergent from those for a steady shock when the thermal history of a shocked gas parcel in the SNR differs significantly from that behind a steady shock. This occurs in shocks with velocities >~ 200 km/s for which the remnant is just beginning to go radiative. Assuming SNRs evolve in a warm phase dominated ISM, we find dust destruction timescales are increased by a factor of ~2 compared to those of Jones et al. (1996), who assumed a hot gas dominated ISM. Recent estimates of supernova rates and ISM mass lead to another factor of ~3 increase in the destruction timescales, resulting in a silicate grain destruction timescale of ~2-3 Gyr. These increases, while not able resolve the problem of the discrepant timescales for silicate grain destruction and creation, are an important step towards understanding the origin, and evolution of dust in the ISM.Comment: 30 pages, 8 figures, accepted for publication in the Astrophysical Journa

The Sun's Journey Through the Local Interstellar Medium: The PaleoLISM and Paleoheliosphere

Over the recent past, the galactic environment of the Sun has differed substantially from today. Sometime within the past ~130,000 years, and possibly as recent as ~56,000 years ago, the Sun entered the tenuous tepid partially ionized interstellar material now flowing past the Sun. Prior to that, the Sun was in the low density interior of the Local Bubble. As the Sun entered the local ISM flow, we passed briefly through an interface region of some type. The low column densities of the cloud now surrounding the solar system indicate that heliosphere boundary conditions will vary from opacity considerations alone as the Sun moves through the cloud. These variations in the interstellar material surrounding the Sun affected the paleoheliosphere.Comment: To be published in Astrophysics and Space Sciences Transactions (ASTRA), for the proceedings of the workshop "Future Perspectives in Heliospheric Research: Unsolved Problems, New Missions - New Sciences" Bad Honnef, Germany, April 6-8, 2005, held in honor of Prof. Hans Fahr's 65th birthda

Elimination of mother- to - child transmission of HIV in South Africa : Rapid scale- up using quality improvement

PKBackground: South Africa (SA) is committed to achieving the goal of eliminating mother-to-child transmission (MTCT) of HIV by 2015. To achieve this, universal coverage of quality antenatal, labour, delivery and postnatal services for all women has to be attained. Over the past decade, the prevention of mother-to-child transmission (PMTCT) programme has been scaled up to reach all healthcare facilities in the country. However, challenges persist in achieving 100% coverage and access to the programme. Objectives: We describe the process undertaken by the National Department of Health (NDoH), in collaboration with partners, to develop, implement and monitor a data-driven intervention to improve facility, district, provincial and national PMTCT-related performance. Methods: Between 2011 and 2013, the NDoH developed and implemented an intervention using data-driven participatory processes to understand facility-level bottlenecks to optimise PMTCT implementation and to scale up priority PMTCT actions nationally. Results: There was remarkable improvement across all key indicators in the PMTCT cascade over the 3 years 2011 - 2013. Simple monitoring tools such as a visual dashboard and data for action reports were successfully used to improve the performance of the PMTCT programme across SA. MTCT has shown a significant downward trend. Conclusions: It is feasible to implement district-level, data-driven quality improvement processes at a national scale to improve the performance of the PMTCT programme at the local level

Exclusion of Tiny Interstellar Dust Grains from the Heliosphere

The distribution of interstellar dust grains (ISDG) observed in the Solar System depends on the nature of the interstellar medium-solar wind interaction. The charge of the grains couples them to the interstellar magnetic field (ISMF) resulting in some fraction of grains being excluded from the heliosphere while grains on the larger end of the size distribution, with gyroradii comparable to the size of the heliosphere, penetrate the termination shock. This results in a skewing the size distribution detected in the Solar System. We present new calculations of grain trajectories and the resultant grain density distribution for small ISDGs propagating through the heliosphere. We make use of detailed heliosphere model results, using three-dimensional (3-D) magnetohydrodynamic/kinetic models designed to match data on the shape of the termination shock and the relative deflection of interstellar neutral H and He flowing into the heliosphere. We find that the necessary inclination of the ISMF relative to the inflow direction results in an asymmetry in the distribution of the larger grains (0.1 micron) that penetrate the heliopause. Smaller grains (0.01 micron) are completely excluded from the Solar System at the heliopause.Comment: 5 pages, 5 figures, accepted for publication in the Solar Wind 12 conference proceeding

Solar wind-magnetosphere coupling and the distant magnetotail: ISEE-3 observations

ISEE-3 Geotail observations are used to investigate the relationship between the interplanetary magnetic field, substorm activity, and the distant magnetotail. Magnetic field and plasma observations are used to present evidence for the existence of a quasi-permanent, curved reconnection neutral line in the distant tail. The distance to the neutral line varies from absolute value of X = 120 to 140 R/sub e near the center of the tail to beyond absolute value of X = 200 R/sub e at the flanks. Downstream of the neutral line the plasma sheet magnetic field is shown to be negative and directly proportional to negative B/sub z in the solar wind as observed by IMP-8. V/sub x in the distant plasma sheet is also found to be proportional to IMF B/sub z with southward IMF producing the highest anti-solar flow velocities. A global dayside reconnection efficiency of 20 +- 5% is derived from the ISEE-3/IMP-8 magnetic field comparisons. Substorm activity, as measured by the AL index, produces enhanced negative B/sub z and tailward V/sub x in the distant plasma sheet in agreement with the basic predictions of the reconnection-based models of substorms. The rate of magnetic flux transfer out of the tail as a function of AL is found to be consistent with previous near-Earth studies. Similarly, the mass and energy fluxes carried by plasma sheet flow down the tail are consistent with theoretical mass and energy budgets for an open magnetosphere. In summary, the ISEE-3 Geotail observations appear to provide good support for reconnection models of solar wind-magnetosphere coupling and substorm energy rates

Anatomically Constrained Video-CT Registration via the V-IMLOP Algorithm

Functional endoscopic sinus surgery (FESS) is a surgical procedure used to treat acute cases of sinusitis and other sinus diseases. FESS is fast becoming the preferred choice of treatment due to its minimally invasive nature. However, due to the limited field of view of the endoscope, surgeons rely on navigation systems to guide them within the nasal cavity. State of the art navigation systems report registration accuracy of over 1mm, which is large compared to the size of the nasal airways. We present an anatomically constrained video-CT registration algorithm that incorporates multiple video features. Our algorithm is robust in the presence of outliers. We also test our algorithm on simulated and in-vivo data, and test its accuracy against degrading initializations.Comment: 8 pages, 4 figures, MICCA