Thirty Meter Telescope Site Testing I: Overview

As part of the conceptual and preliminary design processes of the Thirty Meter Telescope (TMT), the TMT site testing team has spent the last five years measuring the atmospheric properties of five candidate mountains in North and South America with an unprecedented array of instrumentation. The site testing period was preceded by several years of analyses selecting the five candidates, Cerros Tolar, Armazones and Tolonchar in northern Chile; San Pedro Martir in Baja California, Mexico and the 13 North (13N) site on Mauna Kea, Hawaii. Site testing was concluded by the selection of two remaining sites for further consideration, Armazones and Mauna Kea 13N. It showed that all five candidates are excellent sites for an extremely large astronomical observatory and that none of the sites stands out as the obvious and only logical choice based on its combined properties. This is the first article in a series discussing the TMT site testing project.Comment: Accepted for publication in PASP, April 2009 issu

Wide-Field Survey of Globular Clusters in M31. I. A Catalog of New Clusters

We present the result of a wide-field survey of globular clusters (GCs) in M31 covering a 3deg x 3deg field c. We have searched for GCs on CCD images taken with Washington CMT1 filters at the KPNO 0.9 m telescope using steps: (1) inspection of morphological parameters given by the SExtractor package such as stellarity, full maximum, and ellipticity; (2) consulting the spectral types and radial velocities obtained from spectra takena spectrograph at the WIYN 3.5 m telescope; and (3) visual inspection of the images of each object. We have and GC candidates, of which 605 are newly found GCs and GC candidates and 559 are previously known GCs. Amoects there are 113 genuine GCs, 258 probable GCs, and 234 possible GCs, according to our classification critee known objects there are 383 genuine GCs, 109 probable GCs, and 67 possible GCs. In total there are 496 genprobable GCs and 301 possible GCs. Most of these newly found GCs have T1 magnitudes of 17.5 - 19.5 mag, [17.9 < V < 19.9 mag assuming (C-T1) ~ 1.5], and (C-T1) colors in the range 1 - 2.Comment: accepted by AJ, using emulateapj.cl

Multi Aperture Scintillation Sensor (MASS) used in the site selection of the Thirty Meter Telescope (TMT)

One of the main tools used in the TMT site testing campaign is the turbulence profiler MASS. We describe empirical investigations and a side by side comparison of two MASS systems which were performed in order to identify the accuracy of MASS turbulence data and its dependence on the instrument calibration. The accuracy of the total seeing delivered by the TMT MASS systems is found to be better than 0"05. The combination of MASS and DIMM allows to observe the seeing within the first few hundred meters of the atmosphere and can be used to investigate possible correlations with meteorological parameters measured close to the ground. We also compare the detection of clouds and cirrus by means of MASS data (LOSSAM method) with measurements of the thermal emission of clouds using a net radiation sensor. These methods are compared with the visual cloud detection using all sky cameras

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.

The genomic regulatory programmes that underlie human organogenesis are poorly understood. Pancreas development, in particular, has pivotal implications for pancreatic regeneration, cancer and diabetes. We have now characterized the regulatory landscape of embryonic multipotent progenitor cells that give rise to all pancreatic epithelial lineages. Using human embryonic pancreas and embryonic-stem-cell-derived progenitors we identify stage-specific transcripts and associated enhancers, many of which are co-occupied by transcription factors that are essential for pancreas development. We further show that TEAD1, a Hippo signalling effector, is an integral component of the transcription factor combinatorial code of pancreatic progenitor enhancers. TEAD and its coactivator YAP activate key pancreatic signalling mediators and transcription factors, and regulate the expansion of pancreatic progenitors. This work therefore uncovers a central role for TEAD and YAP as signal-responsive regulators of multipotent pancreatic progenitors, and provides a resource for the study of embryonic development of the human pancreas

Organic phosphorus in the terrestrial environment: a perspective on the state of the art and future priorities

Background The dynamics of phosphorus (P) in the environment is important for regulating nutrient cycles in natural and managed ecosystems and an integral part in assessing biological resilience against environmental change. Organic P (Po) compounds play key roles in biological and ecosystems function in the terrestrial environment being critical to cell function, growth and reproduction. Scope We asked a group of experts to consider the global issues associated with Po in the terrestrial environment, methodological strengths and weaknesses, benefits to be gained from understanding the Po cycle, and to set priorities for Po research. Conclusions We identified seven key opportunities for Po research including: the need for integrated, quality controlled and functionally based methodologies; assessment of stoichiometry with other elements in organic matter; understanding the dynamics of Po in natural and managed systems; the role of microorganisms in controlling Po cycles; the implications of nanoparticles in the environment and the need for better modelling and communication of the research. Each priority is discussed and a statement of intent for the Po research community is made that highlights there are key contributions to be made toward understanding biogeochemical cycles, dynamics and function of natural ecosystems and the management of agricultural systems

UNIDAD DE INVESTIGACIÓN EN HOSPITALES AUTOGESTIONADOS

The purpose of this paper is to reflect the importance of research in self-managed health center. It describes the international socio-political context which contributes to the formation of autonomous health centers in a network to reduce inequalities. It discusses the need to include research as a unit or committee within the structures of self-managed hospitals to provide quality care. Finally it emphasizes the need for the population of nurses involved in research committees in the Care Management Unit of the establishment with the aim of innovating practices, improve quality standards in the health center and support the profession.El propósito de este trabajo es reflexionar respecto de la importancia de la investigación en el centro asistencial autogestionado. Se describe el contexto sociopolítico internacional que contribuye a la formación de centros de salud autónomos en red para disminuir las desigualdades. Analiza la necesidad de incluir a la investigación como una unidad o comité dentro de las estructuras de los hospitales autogestionados para proporcionar una atención de calidad. Finalmente destaca la necesidad de que la población de enfermeras/os participe de los comités de investigación en la Unidad de Gestión del Cuidado del establecimiento con el objetivo de innovar en las prácticas, mejorar los estándares de calidad del centro asistencial y sustentar la profesión