A gestão da Dor Aguda

A dor constitui um desafio contínuo ao nível dos cuidados de saúde, sendo a sua intervenção/gestão um direito das pessoas e um dever dos profissionais de saúde. Quando persistente e de elevada intensidade pode prejudicar significativamente a saúde mental e física de um indivíduo, pelo que a avaliação apropriada da dor consiste no primeiro passo para o controlo da mesma. A relação da dor com o sofrimento merece, por isso, uma referência particular, na medida em que a negação e/ou desvalorização da dor do “outro” constitui um erro ético, assim como uma falha na excelência do exercício profissional

Measurement of D*+/- meson production in jets from pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

This paper reports a measurement of D*+/- meson production in jets from proton-proton collisions at a center-of-mass energy of sqrt(s) = 7 TeV at the CERN Large Hadron Collider. The measurement is based on a data sample recorded with the ATLAS detector with an integrated luminosity of 0.30 pb^-1 for jets with transverse momentum between 25 and 70 GeV in the pseudorapidity range |eta| < 2.5. D*+/- mesons found in jets are fully reconstructed in the decay chain: D*+ -> D0pi+, D0 -> K-pi+, and its charge conjugate. The production rate is found to be N(D*+/-)/N(jet) = 0.025 +/- 0.001(stat.) +/- 0.004(syst.) for D*+/- mesons that carry a fraction z of the jet momentum in the range 0.3 < z < 1. Monte Carlo predictions fail to describe the data at small values of z, and this is most marked at low jet transverse momentum.Comment: 10 pages plus author list (22 pages total), 5 figures, 1 table, matches published version in Physical Review

Search for supersymmetry in final states with jets, missing transverse momentum and one isolated lepton in sqrt{s} = 7 TeV pp collisions using 1 fb-1 of ATLAS data

We present an update of a search for supersymmetry in final states containing jets, missing transverse momentum, and one isolated electron or muon, using 1.04 fb^-1 of proton-proton collision data at sqrt{s} = 7 TeV recorded by the ATLAS experiment at the LHC in the first half of 2011. The analysis is carried out in four distinct signal regions with either three or four jets and variations on the (missing) transverse momentum cuts, resulting in optimized limits for various supersymmetry models. No excess above the standard model background expectation is observed. Limits are set on the visible cross-section of new physics within the kinematic requirements of the search. The results are interpreted as limits on the parameters of the minimal supergravity framework, limits on cross-sections of simplified models with specific squark and gluino decay modes, and limits on parameters of a model with bilinear R-parity violation.Comment: 18 pages plus author list (30 pages total), 9 figures, 4 tables, final version to appear in Physical Review

Reducing heterotic M-theory to five dimensional supergravity on a manifold with boundary

This paper constructs the reduction of heterotic $M$-theory in eleven dimensions to a supergravity model on a manifold with boundary in five dimensions using a Calabi-Yau three-fold. New results are presented for the boundary terms in the action and for the boundary conditions on the bulk fields. Some general features of dualisation on a manifold with boundary are used to explain the origin of some topological terms in the action. The effect of gaugino condensation on the fermion boundary conditions leads to a `twist' in the chirality of the gravitino which can provide an uplifting mechanism in the vacuum energy to cancel the cosmological constant after moduli stabilisation.Comment: 16 pages, RevTe

Measurement of tau polarization in W->taunu decays with the ATLAS detector in pp collisions at sqrt(s) = 7 TeV

In this paper, a measurement of tau polarization in W->taunu decays is presented. It is measured from the energies of the decay products in hadronic tau decays with a single final state charged particle. The data, corresponding to an integrated luminosity of 24 pb^-1, were collected by the ATLAS experiment at the Large Hadron Collider in 2010. The measured value of the tau polarization is Ptau = -1.06 +/- 0.04 (stat) + 0.05 (syst) - 0.07 (syst), in agreement with the Standard Model prediction, and is consistent with a physically allowed 95% CL interval [-1,-0.91]. Measurements of tau polarization have not previously been made at hadron colliders.Comment: 10 pages plus author list (25 pages total), 4 figures, 4 tables, revised author list, matches published EPJC versio

Empoderamiento de los jóvenes a través de las redes sociales. Construcción de una ciudadanía digital comprometida

La búsqueda de la implicación y la participación ciudadana en el desarrollo de un sistema social no es un fenómeno nuevo o que haya surgido con la comunicación digital. Sin embargo, las redes sociales y los entornos virtuales están transformando el modo en el que los individuos, y especialmente los jóvenes, se sienten llamados a la acción. La investigación cuantitativa mediante encuestas que se presenta aquí analiza cómo los jóvenes emplean herramientas online y offline para dar a conocer y apoyar las “causas 2.0”. La comunicación digital puede facilitar la cooperación y solidaridad ante determinadas iniciativas sociales que demandan esa movilización activa. Sin embargo, esa ventaja competitiva que puede ofrecer la tecnología se encuentra influenciada por múltiples variables (empatía, proximidad, identificación con la causa…). Resulta imprescindible saber qué es lo que quieren los jóvenes y cuál es el modo de captar su atención para lograr ese compromiso social. Los resultados de este trabajo parecen indicar que lo que moviliza a los jóvenes a la hora de participar en alguna acción solidaria son los aspectos puramente racionales y emocionales, dejando más de lado la propia creatividad de la campaña, la organización que impulsa la acción o la presencia de prescriptores famosos o influenciadores. Prefieren la esencia de las propias acciones sociales.Ensuring citizen involvement and participation in the development of a social system is not a new phenomenon, nor has it emerged with digital communication. However, social networks and virtual environments are transforming the way in which individuals, especially young people, are called to action. This quantitative research paper analyzes how young people use online and offline tools to publicize and support "2.0 causes". Digital communication can facilitate cooperation and solidarity toward certain social initiatives that require active mobilization. However, the competitive advantage that technology can offer is greatly influenced by numerous variables (empathy, closeness, identification with the cause, etc.). It is essential to become familiar with the desires of young people and to find the best ways to gain their attention in order to help them achieve their goals of social commitment. The results of this research suggest that the factors mobilizing young people when they participate in solidarity movements are purely rational and emotional, with less emphasis being placed on the creativity of the campaign, the organization that promotes the action, or the presence of famous prescribers or influencers. They prefer the essential qualities of social activism in itself

Readiness of the ATLAS liquid argon calorimeter for LHC collisions

The ATLAS liquid argon calorimeter has been operating continuously since August 2006. At this time, only part of the calorimeter was readout, but since the beginning of 2008, all calorimeter cells have been connected to the ATLAS readout system in preparation for LHC collisions. This paper gives an overview of the liquid argon calorimeter performance measured in situ with random triggers, calibration data, cosmic muons, and LHC beam splash events. Results on the detector operation, timing performance, electronics noise, and gain stability are presented. High energy deposits from radiative cosmic muons and beam splash events allow to check the intrinsic constant term of the energy resolution. The uniformity of the electromagnetic barrel calorimeter response along eta (averaged over phi) is measured at the percent level using minimum ionizing cosmic muons. Finally, studies of electromagnetic showers from radiative muons have been used to cross-check the Monte Carlo simulation. The performance results obtained using the ATLAS readout, data acquisition, and reconstruction software indicate that the liquid argon calorimeter is well-prepared for collisions at the dawn of the LHC era.ATLAS Collaboration, for complete list of authors see http://dx.doi.org/10.1140/epjc/s10052-010-1354-y</p

Active fold system in the northern continental margin of the Alboran Sea (Western Mediterranean)

En el margen septentrional del Mar de Alborán, la deformación compresiva relacionada con la convergencia entre las placas de Eurasia y Nubia se resuelve mediante una intensa fracturación según dos grandes sistemas de fallas de dirección NNE-SSO con movimiento sinestro y NO-SE de desplazamiento dextral-normal. El análisis estructural de los elementos geomorfológicos presentes en el fondo marino permite establecer, además, una serie de elementos morfológicos generados por la actividad de pliegues anticlinales y sinclinales que conforman una serie de elevaciones de dirección N050-060ºE. Estos pliegues deforman a las unidades sedimentarias superficiales y han sido activos al menos durante el Cuaternario, como lo demuestra el patrón de espesores de las unidades sísmicas afectadas por el plegamiento y la deformación de la superficie erosiva asociada a una terraza contornítica. Este patrón de estructuras se interpreta como generado por la deformación existente sobre una falla de cabalgamiento, vergente hacia el norte, que asume parte de la deformación compresiva causada por la indentación del bloque de la Dorsal de Alborán.In the northern margin of the Alboran Sea, the compressive deformation related to the convergence between the Nubian and Eurasian plates is resolved by an intense fracturing along two large fault systems trending NNE-SSW with left-lateral movements and NW-SE with right-lateral normal components. The structural analysis of the geomorphological elements on the seafloor also allows us to establish a series of morphological elements generated by the activity of some anticline and syncline fold sets. It is basically a series of ridges heading N050-060ºE. These folds deform the shallow sedimentary units and have been active at least during the Quaternary, as evidenced by the thickness pattern of seismic units affected by the folding and the deformation of an erosive surface associated with a contouritic terrace. This pattern of structures is interpreted to be generated by the overlying deformation on a thrust fault, verging towards the north, which assumes part of the compressive deformation caused by the indentation of the Alborán Ridge block.Versión del edito

Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program

Altres ajuts: This work was supported by the Obra Social "La Caixa" (to M. Esteller).Tumors have aberrant proteomes that often do not match their corresponding transcriptome profiles. One possible cause of this discrepancy is the existence of aberrant RNA modification landscapes in the so-called epitranscriptome. Here, we report that human glioma cells undergo DNA methylation-associated epigenetic silencing of NSUN5, a candidate RNA methyltransferase for 5-methylcytosine. In this setting, NSUN5 exhibits tumor-suppressor characteristics in vivo glioma models. We also found that NSUN5 loss generates an unmethylated status at the C3782 position of 28S rRNA that drives an overall depletion of protein synthesis, and leads to the emergence of an adaptive translational program for survival under conditions of cellular stress. Interestingly, NSUN5 epigenetic inactivation also renders these gliomas sensitive to bioactivatable substrates of the stress-related enzyme NQO1. Most importantly, NSUN5 epigenetic inactivation is a hallmark of glioma patients with long-term survival for this otherwise devastating disease